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News: Reminder: BioC2023 in-person registration closes 19th July!
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2.5 years ago Maria Doyle ▴ 110
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News: May 31st is the last day to nominate for Bioc2023 Awards!
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News: Reminder: BioC2023, Awards, TAB Deadline approaching - May 31st!
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2.6 years ago Maria Doyle ▴ 110
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News: Last Week to Nominate for Bioc2023 Awards!
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News: Nominations for Bioconductor 2023 Awards!
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2.8 years ago • updated 2.7 years ago shepherl 4.3k
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News: BioC2023 abstract submission is now open!
presentation BioC2023 Conference community Bioconductor
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News: Seeking members for BioC2023 organizing committee
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3.0 years ago Maria Doyle ▴ 110
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News: Save the Date Bioc2023!
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3.2 years ago shepherl 4.3k
11 results • Page 1 of 1
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Comment: DESeq2 - how many surrogate variables from svaseq, use of lfcshrink by ja569116 • 0
Hi @atpoint Thanks for the information. Could you please expand on when to use adjusted p-values vs nominal p-values. My understanding was …
Answer: limpa analysis advice by Gordon Smyth 53k
It is actually very hard to estimate the DPC from observed data, because the curve is function of unobserved intensities rather than a func…
Answer: When to use edgeR or limma by Gordon Smyth 53k
The short answer is that we generally prefer edgeR for applications with lots of small counts and limma for complex designs with random eff…
Comment: limpa-blank normalization and Spectronaut's PTM stoichiometry by Gordon Smyth 53k
I updated the above answer today.
Answer: When to use edgeR or limma by James W. MacDonald 68k
I would use edgeR's quasi-likelihood model for any analysis with a smaller number of observations (like 3 vs 3 or similar), but if you have…
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Answer: When to use edgeR or limma
Answer: When to use edgeR or limma
Answer: When to use edgeR or limma
Answer: When to use edgeR or limma
A: deseq2 - paired samples in 2 sequencing types with very different library sizes
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