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21.3 years ago • updated 10 months ago Gordon Smyth 50k

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Comment: SGSeq: moving toward diffex from SGSeq analysis by Sara • 0

Thank you for your response. I have another question about saving the sgvc result as a CSV file. I would appreciate your help, please. ``` …

Comment: How to use bootRanges to bootstrap small RNA loci (nullranges package) by Poonam • 0

I tried different block lengths first and considered 100000 to be ideal because of the almost similar inter-range distance. S1= bootRange…

Comment: How to use bootRanges to bootstrap small RNA loci (nullranges package) by Michael Love 41k

The segmentation and block length are key parameters. We recommend for example blocks of length ~500kb. It would help if you would post yo…

Answer: Handling multiple differential expression comparisons by Michael Love 41k

It's typical that results are presented with each group having its own FDR control. So presenting each comparison with the adjusted p-va…

Comment: Too many significant genes when integrating gtex and tcga by ATpoint ★ 4.1k

These two datasets are from completely different experiments / batches. It is utterly meaningless to compare them. I would suggest comparat…

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package goseq seems to be not available on the latest version of R

Print Differentially Expressed Exons From Dexseq Results

Answer: Why does GSEA on edgeR results for randomized samples give highly significant p-

Answer: limma Intercept vs No-intercept models completely changing DMR results?

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