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MutationalPatterns
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1.8k
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Error in seqlevelsStyle after creating a BSgenome package
bsgenome
MutationalPatterns
4.1 years ago • updated 4.0 years ago
sibyl.bertrand
• 0
2
votes
2
replies
992
views
MutationalPatterns Signature Database Versions
MutationalPatterns
3.0 years ago
Dario Strbenac
★ 1.5k
0
votes
0
replies
1.4k
views
Error in NMF estimation
MutationalPatterns
NMF
5.0 years ago
TRASA
• 0
0
votes
0
replies
663
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Do you know a sofware to draw pedigrees + haplotypes?
SequencingData
STR
MutationalPatterns
pedigree
HapMap
2.8 years ago
Negar
• 0
0
votes
2
replies
605
views
could not find function "get_known_signatures"
MutationalPatterns
updated 17 months ago by
Vincent J. Carey, Jr.
6.7k • written 17 months ago by
anton.kratz
▴ 60
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Answer: How to use bootRanges to bootstrap small RNA loci (nullranges package)
by
Poonam
• 0
Hi Michael, I think there is something wrong with the generation of nullranges. I was working with small RNA and methylation overlaps. …
Answer: Once again a "Model matrix not full rank"
by
swbarnes2
★ 1.3k
Replicate numbers, like the 1 in control_1 are fine in sample names, but never add them to anything else in colData. From the computer's p…
Answer: limma Intercept vs No-intercept models completely changing DMR results?
by
Gordon Smyth
50k
I'll add a little bit of general advice to James' answer. You seem to have the misunderstanding that you can change the design matrix but …
Answer: package goseq seems to be not available on the latest version of R
by
Gordon Smyth
50k
It is true that goseq isn't available for Bioc 3.19 (as at 4 May 2024). In the meantime, you could consider using the goana() and kegga() …
Answer: limma Intercept vs No-intercept models completely changing DMR results?
by
James W. MacDonald
65k
This part: ``` design_intercept <- model.matrix(~Alt+Sex+Age+PC1, data=targets_Sherpa) colnames(design_intercept) <- c("AltSHP_LA","Al…
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Answer: Why does GSEA on edgeR results for randomized samples give highly significant p-
Answer: limma Intercept vs No-intercept models completely changing DMR results?
Answer: CombineArrays for EPIC and EPIC V2
Answer: Too many significant genes when integrating gtex and tcga
Comment: Too many significant genes when integrating gtex and tcga
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