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Recent ...
Replies
Comment: DESeq2, why are the signs of EDASeq offsets flipped compared to CQN ?
by
Saulius
•
0
Yes - I think you are right once more. Thanks for taking so much time to look into this.
Size factors come in twice in the code of `cqn`: …
Comment: DESeq2, why are the signs of EDASeq offsets flipped compared to CQN ?
by
Michael Love
32k
Re: (2), I read the code and docs as adding in library size scaling, not removing.
This is because, after (1) the offset is in the directi…
Comment: DESeq2, why are the signs of EDASeq offsets flipped compared to CQN ?
by
Saulius
•
0
Yes - this is the key I now realise.
The last section of the vignette does not really explain how exactly `glm.offset` is different, nor s…
Answer: edgeR & blocking with complex experimental design
by
Yunshun Chen
▴
720
I wouldn't recommend the exact test as it can't handle complex designs like the one you have.
Your second approach is equivalent to fitt…
Comment: Error wth Installation BiocManager
by
beaferbl
•
0
No, it cannot open the connection. Anyway, thanks for your help. I'll post the answer when I fix it.
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