filtering options in RnBeads for array data
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Jitendra ▴ 10
@nabiyogesh-11718
Last seen 4 months ago
United Kingdom

Hi,

I am bit confused with filtering option for greedycut in RnBeads, could you please help what options need to set for array methylation datasets;

 *‘filtering.greedycut’*‘ = NULL’ Flag indicating if the Greedycut
      procedure should be run as a filtering step in the
      preprocessing module.  ‘NULL’ (default) indicates that
      Greedycut will be run for array-based datasets, but not for
      sequencing-based datasets.

 *‘filtering.greedycut.pvalue.threshold’*‘ = 0.05’ Threshold for
      the detection p-value to be used in Greedycut. This is a
      value between 0 and 1. This option has effect only when
      ‘filtering.greedycut’ is ‘TRUE’.

 *‘filtering.greedycut.rc.ties’*‘ = "row"’ Indicator of what the
      behaviour of Greedycut should be in case of ties between the
      scores of rows (probes) and columns (samples). The value of
      this option must be one of ‘"row"’, ‘"column"’ or ‘"any"’;
      the last one indicating random choice. This option has effect
      only when ‘filtering.greedycut’ is ‘TRUE’.

``` Many thanks, nabiyogesh

Epigenetics RnBeads MethylationArrayData methylationArrayAnalysis • 886 views
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