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Job:
Data Manager - BC Cancer Research Center, Vancouver BC
computational
genomic
big data
bioinformatics
Job
4.9 years ago
jmaanaki
• 0
0
votes
0
replies
949
views
Job:
Postdoctoral positions in drug discovery and genome data science
computational biology
biostatistics
big data
data science
drug discovery
Job
5.2 years ago
Thomas Girke
★ 1.7k
0
votes
0
replies
1.3k
views
Job:
Postdoc and PhD student in Bioinformatics/Biostatistics
NGS
R
statistics
genomics
big data
Job
5.2 years ago • updated 4.4 years ago
Luo Weijun
★ 1.6k
1
vote
2
replies
923
views
How to handle big data sets (>10GB) in Bioconductor packages?
big data
methylmix
memory problem
updated 5.7 years ago by
Martin Morgan
25k • written 5.7 years ago by
perdedorium
• 0
1
vote
1
reply
1.1k
views
Subsetting Rle with ORF-sequence-positions by the 3 frames
Rle
Big data
coverageByTranscript
6.0 years ago
hauken_heyken
▴ 80
0
votes
0
replies
1.3k
views
What is the recommended method for running WGCNA on large metatranscriptomic dataset?
wgcna
transcriptome
big data
metagenomics
gene expression
6.2 years ago
jol.espinoz
▴ 40
3
votes
1
reply
1.3k
views
AnnotationHub: confusing pValue/qValue for (some) Roadmap records
roadmap project
annotationhub
epigenomics
big data
updated 8.0 years ago by
Valerie Obenchain
★ 6.8k • written 8.0 years ago by
kevin.rue
▴ 350
0
votes
0
replies
2.1k
views
Job:
Postdoctoral Research Associate Position- Harvard Medical School (Probabilistic Algorithms and Software for Biomedical Big Data)
Probabilistic Algorithms
Big Data
Job
9.0 years ago
Doe, Aimee
▴ 40
8 results • Page
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Answer: How to use bootRanges to bootstrap small RNA loci (nullranges package)
by
Poonam
• 0
Hi Michael, I think there is something wrong with the generation of nullranges. I was working with small RNA and methylation overlaps. …
Answer: Once again a "Model matrix not full rank"
by
swbarnes2
★ 1.3k
Replicate numbers, like the 1 in control_1 are fine in sample names, but never add them to anything else in colData. From the computer's p…
Answer: limma Intercept vs No-intercept models completely changing DMR results?
by
Gordon Smyth
50k
I'll add a little bit of general advice to James' answer. You seem to have the misunderstanding that you can change the design matrix but …
Answer: package goseq seems to be not available on the latest version of R
by
Gordon Smyth
50k
It is true that goseq isn't available for Bioc 3.19 (as at 4 May 2024). In the meantime, you could consider using the goana() and kegga() …
Answer: limma Intercept vs No-intercept models completely changing DMR results?
by
James W. MacDonald
65k
This part: ``` design_intercept <- model.matrix(~Alt+Sex+Age+PC1, data=targets_Sherpa) colnames(design_intercept) <- c("AltSHP_LA","Al…
Votes
Answer: Why does GSEA on edgeR results for randomized samples give highly significant p-
Answer: limma Intercept vs No-intercept models completely changing DMR results?
Answer: CombineArrays for EPIC and EPIC V2
Answer: Too many significant genes when integrating gtex and tcga
Comment: Too many significant genes when integrating gtex and tcga
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