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cancerdata
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Job:
Postdoc for computational biology on cancer omics data analysis at Liang lab of Wistar Institute, Philadelphia, US
omics
cancerdata
Pathways
2.0 years ago
omicsresearch
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0
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2
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2.9k
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Error with TCGA package - TCGAbiolinks
TCGAbiolinks
RNASeq
CancerData
updated 3.4 years ago by
Tiago C. Silva
▴ 270 • written 3.6 years ago by
JAcky
• 0
2
votes
3
replies
2.3k
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Aggregating genes from multiple GSE's, ranking them, then building a PPI network.
GEOquery
CancerData
limma
RCy3
CancerInSilico
updated 4.2 years ago by
Steve Lianoglou
★ 13k • written 4.2 years ago by
Caitlin
▴ 50
1
vote
1
reply
1.8k
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Extracting a list of genes from the Gene Expression Omnibus with Geoquery.
Microarray
GEOquery
cancerdata
MicroarrayData
updated 4.3 years ago by
James W. MacDonald
68k • written 4.3 years ago by
Caitlin
▴ 50
0
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0
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1.2k
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Job:
PDRA in Computational Biophysics and Cancer Research, University of Manchester, UK
CancerData
StructuralGenomics
VirusStability
pH-dependence
4.4 years ago
jim.warwicker
• 0
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Comment: DESeq2 - how many surrogate variables from svaseq, use of lfcshrink
by
ja569116
• 0
Hi @atpoint Thanks for the information. Could you please expand on when to use adjusted p-values vs nominal p-values. My understanding was …
Answer: limpa analysis advice
by
Gordon Smyth
53k
It is actually very hard to estimate the DPC from observed data, because the curve is function of unobserved intensities rather than a func…
Answer: When to use edgeR or limma
by
Gordon Smyth
53k
The short answer is that we generally prefer edgeR for applications with lots of small counts and limma for complex designs with random eff…
Comment: limpa-blank normalization and Spectronaut's PTM stoichiometry
by
Gordon Smyth
53k
I updated the above answer today.
Answer: When to use edgeR or limma
by
James W. MacDonald
68k
I would use edgeR's quasi-likelihood model for any analysis with a smaller number of observations (like 3 vs 3 or similar), but if you have…
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Answer: When to use edgeR or limma
Answer: When to use edgeR or limma
Answer: When to use edgeR or limma
Answer: When to use edgeR or limma
A: deseq2 - paired samples in 2 sequencing types with very different library sizes
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