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Batch Correction
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3
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3
replies
2.0k
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fastMNN based correction for large multi-run experiment requires a similar population set in all the individual datasets?
scrna-seq
integration
batch correction
updated 5.2 years ago by
Aaron Lun
★ 28k • written 5.2 years ago by
p.joshi
▴ 40
0
votes
1
reply
1.4k
views
Batch correction in Linear Models for methylation data
methylation
ComBat
Linear models
batch correction
AIC
updated 5.3 years ago by
Kevin Blighe
★ 4.0k • written 5.3 years ago by
lucasmiranda42
• 0
5
votes
3
replies
840
views
batch correction in DESeq2 > matrix not full rank > mitigate
DESeq2
batch correction
updated 5.4 years ago by
James W. MacDonald
68k • written 5.4 years ago by
MT
▴ 10
0
votes
3
replies
1.2k
views
Diffbind batch effect blocking error
Diffbind
ATAC
batch correction
blocking factor
updated 5.6 years ago by
Rory Stark
★ 5.2k • written 5.6 years ago by
rm1238
• 0
1
vote
1
reply
1.2k
views
All Pairwise Comparisons with DESeq2 While Controlling for Batch Effects: Does Reference Level Matter?
deseq2
differential expression
batch correction
design
updated 5.8 years ago by
Michael Love
43k • written 5.8 years ago by
wunderl
▴ 40
4
votes
4
replies
1.8k
views
Batch Correction: DESeq2 Linear Model vs Batch-Correction-Specific Algorithms (RUV, ComBat, ect.)
deseq2
differential expression
batch correction
updated 5.8 years ago by
Michael Love
43k • written 5.8 years ago by
wunderl
▴ 40
4
votes
5
replies
2.3k
views
Using SC3 with batch corrected MNN values
SC3
Scater
Scran
scRNA-Seq
Batch Correction
updated 6.0 years ago by
Vladimir Kiselev
▴ 150 • written 6.0 years ago by
hamza_karakurt
▴ 60
7 results • Page
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Answer: best way to grouping GSM belonging to different datasets (with different platfor
by
James W. MacDonald
68k
The only defensible way is to make comparisons within experiments and then do a meta-analysis. But that assumes you have identified multipl…
Comment: DESeq2 estimateSizeFactors with control genes
by
sofia.rigou
• 0
I am also trying to use this function to estimate sizefactor based on RT-dPCR data but estimateSizeFactor only takes integers. Should I mul…
Comment: DiffBind custom normalization factor
by
Abbie
• 0
Hello! Thanks so much for adding dba.normalize and all the documentation in the manual! I'm hoping I can ask a follow-up question here. I…
Answer: CpGs with genomic positions greater than the chromosome size in EPICv2?
by
James W. MacDonald
68k
All of the annotation packages provided by Bioconductor are simply repackaging of existing data from one or more sources. In this case, the…
Comment: Using TPM from tximport of Salmon output for singscore
by
Kent
• 0
Thank you for the suggestions Michael. Would you say that after filtering out the low count genes, `rlog(counts, blind = T)` is doing the s…
Votes
clusterProfiler-GO enrichment Error
A: Machine learning in R book
Data preparation and Machine learning on time course RNAseq data
Data preparation and Machine learning on time course RNAseq data
Answer: Use of org.Rn.eg.db with GRCr8 reference genome
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