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Job: Postdoc and PhD student in Bioinformatics/Biostatistics
NGS R statistics genomics big data Job
4.8 years ago • updated 4.0 years ago Luo Weijun ★ 1.6k
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Job: Data Manager - BC Cancer Research Center, Vancouver BC
computational genomic big data bioinformatics Job
4.5 years ago jmaanaki • 0
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Job: Postdoctoral positions in drug discovery and genome data science
computational biology biostatistics big data data science drug discovery Job
4.8 years ago Thomas Girke ★ 1.7k
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How to handle big data sets (>10GB) in Bioconductor packages?
big data methylmix memory problem
updated 5.3 years ago by 25k • written 5.3 years ago by • 0
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Subsetting Rle with ORF-sequence-positions by the 3 frames
Rle Big data coverageByTranscript
5.6 years ago hauken_heyken ▴ 80
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What is the recommended method for running WGCNA on large metatranscriptomic dataset?
wgcna transcriptome big data metagenomics gene expression
5.8 years ago jol.espinoz ▴ 40
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AnnotationHub: confusing pValue/qValue for (some) Roadmap records
roadmap project annotationhub epigenomics big data
updated 7.6 years ago by ★ 6.8k • written 7.6 years ago by ▴ 320
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Job: Postdoctoral Research Associate Position- Harvard Medical School (Probabilistic Algorithms and Software for Biomedical Big Data)
Probabilistic Algorithms Big Data Job
8.6 years ago Doe, Aimee ▴ 40
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Comment: Small RNA-seq Analysis DESEQ2 : Unexpected Significance by samer • 0
By applying the log2 transformation to the raw counts of small RNAS AND after adding 1 to each count, the resulting values often approximat…
Comment: Small RNA-seq Analysis DESEQ2 : Unexpected Significance by samer • 0
and sometimes in other count plots we observe a difference between the counts of the 2 conditions (ON/OFF) where it should be significant b…
Comment: Small RNA-seq Analysis DESEQ2 : Unexpected Significance by ATpoint ★ 3.6k
What is `Log2 Counts + 1`? Please show code for the plots. And please remove the comments and move everything to the toplevel question usin…
Comment: Small RNA-seq Analysis DESEQ2 : Unexpected Significance by samer • 0
However, when examining the count plots, I've observed a frequent occurrence of significant adjusted p-values between conditions particular…
Comment: Can the limma package be applied to Log2 RUV-normalized data? by Shaimaa Gamal • 0
I see. Do you recommend a certain method to get norm.factors through calcNormFactors function espcially if the downstream analysis includes…
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Comment: Can the limma package be applied to Log2 RUV-normalized data?
Comment: Can the limma package be applied to Log2 RUV-normalized data?
Answer: Correct the batch effect in methylation analysis in R
Comment: Why is DMRcate not available for Bioconductor version 3.18?
Answer: Correct the batch effect in methylation analysis in R
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