Bioconductor Big data

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1.7k

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NGS R statistics genomics big data Job

7.0 years ago • updated 6.1 years ago Luo Weijun ★ 1.6k

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1.3k

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computational genomic big data bioinformatics Job

6.6 years ago jmaanaki • 0

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1.4k

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computational biology biostatistics big data data science drug discovery Job

6.9 years ago Thomas Girke ★ 1.7k

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big data methylmix memory problem

updated 7.4 years ago by Martin Morgan 25k • written 7.4 years ago by perdedorium • 0

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Rle Big data coverageByTranscript

7.8 years ago hauken_heyken ▴ 80

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wgcna transcriptome big data metagenomics gene expression

7.9 years ago jol.espinoz ▴ 40

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1.8k

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roadmap project annotationhub epigenomics big data

updated 9.7 years ago by Valerie Obenchain ★ 6.8k • written 9.7 years ago by kevin.rue ▴ 350

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2.6k

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Probabilistic Algorithms Big Data Job

10.8 years ago Doe, Aimee ▴ 40

8 results • Page 1 of 1

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Comment: Combining two proteomics datasets with limpa by Andrew Pattison • 0

Thanks heaps Gordon. I went with option 1 and no normalisation and all seems to have worked well. Cheers, Andrew

Comment: limpa-blank normalization and Spectronaut's PTM stoichiometry by Gordon Smyth 53k

Flagging protein groups as likely contaminants in this way will be fine for a limpa analysis. The `Cont_` proteins can optionally stay in f…

Answer: Making a Full Rank Model for Allele-Specific Expression with DESeq2 by Gordon Smyth 53k

Aaron Lun was a PhD student in my Lab back in 2015, when he posted the answers about allele-specific expression that you and Mike Love have…

Comment: Making a Full Rank Model for Allele-Specific Expression with DESeq2 by Michael Love 43k

You just need the mouse identifier (controls baseline) and the group specific allelic effect.

Comment: limpa-blank normalization and Spectronaut's PTM stoichiometry by Julia Broadbent • 0

Hi Emily, Just sharing a resource for handling contaminants - we use the methods described in [Frankenfield et al. (2022)](https://pubs.acs…

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A: Filtering read counts matrix: how to deal with duplicated gene symbols, differen

Comment: limpa analysis advice

Answer: When to use edgeR or limma

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