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model matrix
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1.6k
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Model matrix for longitudinal pairwise rna-seq data: linear regression or linear mixed model?
limma
model matrix
linear regression
6.6 years ago • updated 6.5 years ago
agm
• 0
1
vote
2
replies
2.0k
views
DESeq2 design & model matrix not full rank - am I nesting correctly?
deseq2
model matrix
experimental design
multiple factor design
updated 8.0 years ago by
Michael Love
43k • written 8.0 years ago by
amye107
• 0
0
votes
7
replies
2.0k
views
Model matrix not full rank
deseq2
linear combination
model matrix
updated 8.2 years ago by
Michael Love
43k • written 8.2 years ago by
sally_b86
• 0
2
votes
4
replies
1.7k
views
Removing batch effect on edgeR when interactons are looked at
rnaseq
edger
statistics
model matrix
updated 8.3 years ago by
Steve Lianoglou
★ 13k • written 8.3 years ago by
David R
▴ 90
3
votes
6
replies
31k
views
Designing a contrast in DESEQ
deseq2
design and contrast matrix
model matrix
8.9 years ago
mrigaya.mehra
▴ 10
0
votes
8
replies
2.4k
views
DESeq2 glibc error
deseq2
differential gene expression
model matrix
updated 8.9 years ago by
Michael Love
43k • written 8.9 years ago by
gregory.l.stone
▴ 10
4
votes
6
replies
3.2k
views
Find if a covariate has effect on gene expression level using edgeR and DESeq2
edger
deseq2
model matrix
differential expression
9.4 years ago
ta65
• 0
2
votes
7
replies
3.8k
views
ballgown custom models
ballgown
linear model
model matrix
custom model
9.8 years ago • updated 9.7 years ago
sbcn
▴ 80
7
votes
6
replies
4.8k
views
Design and contrast question limma (additive or nested or duplicateCorrelation())??
limma
model matrix
limma design matrix
complex-design
updated 10.6 years ago by
Aaron Lun
★ 29k • written 10.6 years ago by
Guido Hooiveld
★ 4.1k
9
votes
2
replies
6.1k
views
Limma Model Matrix Understanding
limma
limma design matrix
model matrix
updated 10.7 years ago by
Aaron Lun
★ 29k • written 10.7 years ago by
andrew.j.skelton73
▴ 370
2
votes
5
replies
4.8k
views
design model matrix for nested factors (edgeR)
edger
design matrix
model matrix
updated 10.8 years ago by
Aaron Lun
★ 29k • written 10.8 years ago by
silvia.paolucci81
• 0
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Comment: DESeq2 - how many surrogate variables from svaseq, use of lfcshrink
by
ja569116
• 0
Hi @atpoint Thanks for the information. Could you please expand on when to use adjusted p-values vs nominal p-values. My understanding was …
Answer: limpa analysis advice
by
Gordon Smyth
53k
It is actually very hard to estimate the DPC from observed data, because the curve is function of unobserved intensities rather than a func…
Answer: When to use edgeR or limma
by
Gordon Smyth
53k
The short answer is that we generally prefer edgeR for applications with lots of small counts and limma for complex designs with random eff…
Comment: limpa-blank normalization and Spectronaut's PTM stoichiometry
by
Gordon Smyth
53k
I updated the above answer today.
Answer: When to use edgeR or limma
by
James W. MacDonald
68k
I would use edgeR's quasi-likelihood model for any analysis with a smaller number of observations (like 3 vs 3 or similar), but if you have…
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Answer: When to use edgeR or limma
Answer: When to use edgeR or limma
Answer: When to use edgeR or limma
Answer: When to use edgeR or limma
A: deseq2 - paired samples in 2 sequencing types with very different library sizes
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