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22.1 years ago • updated 21 months ago
Gordon Smyth
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Comment: DiffBind custom normalization factor
by
Abbie
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0
Hello!
Thanks so much for adding dba.normalize and all the documentation in the manual! I'm hoping I can ask a follow-up question here.
I…
Answer: CpGs with genomic positions greater than the chromosome size in EPICv2?
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James W. MacDonald
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All of the annotation packages provided by Bioconductor are simply repackaging of existing data from one or more sources. In this case, the…
Comment: Using TPM from tximport of Salmon output for singscore
by
Kent
•
0
Thank you for the suggestions Michael. Would you say that after filtering out the low count genes, `rlog(counts, blind = T)` is doing the s…
Comment: Using TPM from tximport of Salmon output for singscore
by
Michael Love
43k
For clustering generally we recommend `vst()` see the workflow for example.
For working with individual samples, I can see how a scaling/t…
Comment: DESeq2 model - How to test case/control time course model when taking account wi
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Michael Love
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I'd recommend working with a local statistician or someone familiar with linear models in R. I have to reserve my time on the support site …
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