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Robert Castelo
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18 days ago • updated 15 days ago
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updated 19 days ago by
Gordon Smyth
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20 days ago • updated 15 days ago
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Comment: Extremely small p-values using Limma for proteomic data
by
Robert Castelo
★
3.3k
From the point of view of visualization, I find handy the fact that raw p-values give more resolution than adjusted ones, which allows one …
Comment: deseq2 results
by
ATpoint
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4.1k
> the results are not satisfactory to me
Well, what is your question? The DESeq2 vignette covers how to do analysis, and some diagnostics…
Comment: Extremely small p-values using Limma for proteomic data
by
ATpoint
★
4.1k
It's not an implementation problem I am discussing (it's trivial obviously) -- more that for most purposes the y-axis metric should be the …
Comment: Extremely small p-values using Limma for proteomic data
by
Robert Castelo
★
3.3k
For visualization purposes you can draw an horizontal line at the p-value cutoff that meets the experiment-wide FDR cutoff. For instance, i…
Comment: Getting Error in hclust(d, method = method): NA/NaN/Inf in foreign function call
by
ATpoint
★
4.1k
Ask yourself the question how a gene that is exactly the same everywhere adds anything to any analysis. Heatmaps usually take DEGs to infer…
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