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saddamhusain77
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1.6k
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1.8k
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updated 5.8 years ago by
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Kevin Blighe
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jeroen.gilis
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phoebe1354
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updated 15 months ago by
Mary-Ellen
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written 5.3 years ago by
fiona.dick91
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3
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1.4k
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updated 5.6 years ago by
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90
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zoe.ward
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Michael Love
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Jack.Hearn
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updated 7.3 years ago by
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written 7.3 years ago by
kristoffer.vittingseerup
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georgewwp
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838
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180
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sdvie
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90
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Recent ...
Replies
Answer: Numerical differences in DESeq2 output depending on different design matrix cons
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Yes there can be small numerical differences in the estimated quantities because of how the algorithms decide to stop iterating.
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Removing samples from one group nevertheless changes the variance estimation (dispersion) for all comparisons. So you could have pushed one…
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If you restrict yourself to, say, genes with a baseMean > 50, are the numerical differences between the two designs significant?
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