Showing : StatisticalMethod • reset
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137
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Detecting genomic signatures of drug resistance breast cancer in transcriptomic data
TransOmicsData signatureSearchData StatisticalMethod
updated 16 days ago by 67k • written 16 days ago by • 0
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1
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331
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Can we compare 3 different experimental conditions with DESeq2?
DESeq2 StatisticalMethod
updated 6 months ago by ★ 1.4k • written 6 months ago by • 0
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270
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Job: Post-Doc: Development of a new method to study the distribution of the effect sizes of QTL
StatisticalMethod Evolution QuantitativeTrailLocus Genetics JobPosting
6 months ago pierre.devillemereuil • 0
0
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3
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766
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Differences in differential analysis methods for RNA-Seq
DESeq2 StatisticalMethod Proteomics DifferentialExpression RNASeq
updated 7 months ago by ★ 4.6k • written 7 months ago by • 0
2
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2
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1.9k
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DESeq2 median of ratios normalization instead of VST or rlog for ordinations?
DESeq2 medianofratiostransformation StatisticalMethod Normalization dispersion
11 months ago Linton • 0
1
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2
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850
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How to perform longitudinal analysis using EdgeR
StatisticalMethod FoldChange edgeR RNASeq
11 months ago Sabiha ▴ 20
2
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2
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695
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DESeq2: Comparison of single clinical sample to 4 normals using tumour cohort to infer dispersion of single sample
GeneExpression DESeq2 RNASeqData RNASeq StatisticalMethod
12 months ago Manthos • 0
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2
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1.3k
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DecideTest vs topTAGs in edgeR
RNAseq StatisticalMethod edgeR
updated 13 months ago by 52k • written 13 months ago by ▴ 10
3
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2
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885
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Does this RNAseq experiment require a repeated measures approach?
StatisticalMethod RNASeqData edgeR DESeq2
updated 17 months ago by 52k • written 17 months ago by ▴ 10
2
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3
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2.7k
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deseq2 normalization and statistical method
normalization deseq2 StatisticalMethod
updated 20 months ago by ★ 4.6k • written 20 months ago by ▴ 10
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4
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959
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Model comparison in mean-dispersion trend in DESeq2
DESeq2 StatisticalMethod
21 months ago Loïc • 0
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2
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960
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Using Multi-Dimensional Scaling (MDS) to produce a vector in order to account for patient bias when constructing DGE lists from RNA-seq datasets in R?
PrincipalComponent StatisticalMethod edgeR MultidimensionalScaling Normalization
21 months ago rcreswell01 • 0
1
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3
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1.2k
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Limma-voom with inverse probability weights (similar to sample weights)
limma limma-voom StatisticalMethod
updated 22 months ago by 52k • written 22 months ago by ▴ 10
0
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1
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666
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DESeq2 paired multifactor test
DESeq2 StatisticalMethod
updated 2.0 years ago by 43k • written 2.1 years ago by ▴ 10
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0
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798
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Job: Academic position in Non-clinical Biostatistics
JobPosting StatisticalMethod
2.1 years ago Laurent Gatto 1.6k
1
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1.3k
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Limma adj.p.value the same for many different p.values
limmaGUI limma adj.p.value StatisticalMethod
2.2 years ago walkerrh95 • 0
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0
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1.1k
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Job: Postdoctoral research scientist in computational biology/statistical genetics/functional genomics at Columbia University, USA
Alzheimer's StatisticalMethod Genetics molecularQTL FunctionalGenomics
2.2 years ago gaow • 0
0
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0
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692
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Should I adjust p value for multi-levels (groups) and multi-variables?
StatisticalMethod
2.7 years ago dong ▴ 10
2
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3
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4.5k
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Differential gene expression and (adjusted) p-values
edgeR StatisticalMethod
updated 2.6 years ago by • 0 • written 2.9 years ago by • 0
6
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4
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1.2k
views
Limma prametrization
limm MathematicalBiology limmaGUI StatisticalMethod
2.9 years ago Giovanni • 0
2
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7
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1.8k
views
EdgeR, tumor normal pair, no replicatie but multiple patients, to focus on individual patients not combined
edgeR StatisticalMethod
3.2 years ago Field -Ye • 0
0
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2
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1.7k
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To retrieve the transcript from gff file with the longest isoform
FunctionalAnnotation StatisticalMethod
3.5 years ago Aneesha • 0
0
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1
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899
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DESeq2 Design matrix
StatisticalMethod DESeq2
updated 3.6 years ago by 43k • written 3.6 years ago by • 0
6
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6
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2.0k
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limma:arrayWeights() and the "prior.n" parameter for biological replicates? (PROTEOMICS)
Proteomics limma StatisticalMethod
updated 3.7 years ago by 52k • written 3.7 years ago by ▴ 10
1
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3
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1.3k
views
How to assign random effect factor in DESeq2 desing?
StatisticalMethod DESeq2 phyloseq
updated 3.8 years ago by 43k • written 3.8 years ago by • 0
0
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0
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1.4k
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Why is `scale-free topology` estimated as -sign(slope) * (R^2) in WGCNA?
Network StatisticalMethod WGCNA ExpressionData
3.9 years ago jol.espinoz ▴ 40
0
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2
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864
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p adjusted value not available
StatisticalMethod DESeq2
updated 4.1 years ago by ★ 4.0k • written 4.1 years ago by • 0
27 results • Page 1 of 1
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Comment: Running multiple KNN queries in parallel by SamGG ▴ 360
Thank you for your detailed answer, I appreciate it and your work.
Answer: Running multiple KNN queries in parallel by Aaron Lun ★ 28k
That is correct - you can't pass the prebuilt objects to different processes. Maybe `MulticoreParam()` might work on POSIX systems but I'm …
Answer: RSubread output significantly different from bash Subread output by Gordon Smyth 52k
The difference (as ATpoint has correctly pointed out) is that Rsubread::featureCounts counts multi-mapping reads by default whereas the com…
Answer: Deseq2 Error in solve.default(qr.R(qrx)) : 'a' (1 x 0) must be square by Michael Love 43k
I would check the rank of your model matrix, and perhaps meet with a local statistician who can help you create an appropriate design matri…
Comment: sva: get a sv for RIN scores by gabriel.hoffman ▴ 170
Agreed. I'll add that with small sample size, a covariate can explain some fraction of expression variation even under the null.
Votes
Answer: Running multiple KNN queries in parallel
Answer: Running multiple KNN queries in parallel
Answer: RSubread output significantly different from bash Subread output
Answer: RSubread output significantly different from bash Subread output
Answer: How to annotate a limma Elist raw class object with an annotation file
Awards • All
Popular Question to Gordon Smyth 52k
Scholar to Aaron Lun ★ 28k
Teacher to Michael Love 43k
Popular Question to Dario Strbenac ★ 1.5k
Scholar to ATpoint ★ 4.6k
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