Showing : StatisticalMethod • reset
3
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4
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661
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p-adjusted values in multiple comparisons
StatisticalMethod limma RnaSeqSampleSizeData
updated 4 months ago by • 0 • written 5 months ago by • 0
0
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278
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Correlation threshold
MethylationArray methylationArrayAnalysis StatisticalMethod
10 months ago user_bioinfo • 0
1
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2
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526
views
Detecting genomic signatures of drug resistance breast cancer in transcriptomic data
TransOmicsData signatureSearchData StatisticalMethod
written 14 months ago by • 0
0
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1
reply
782
views
Can we compare 3 different experimental conditions with DESeq2?
DESeq2 StatisticalMethod
updated 20 months ago by ★ 1.4k • written 20 months ago by • 0
0
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0
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698
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Job: Post-Doc: Development of a new method to study the distribution of the effect sizes of QTL
StatisticalMethod Evolution QuantitativeTrailLocus Genetics JobPosting
21 months ago pierre.devillemereuil • 0
0
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3
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1.8k
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Differences in differential analysis methods for RNA-Seq
DESeq2 StatisticalMethod Proteomics DifferentialExpression RNASeq
updated 21 months ago by ★ 5.0k • written 21 months ago by • 0
2
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2
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4.5k
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DESeq2 median of ratios normalization instead of VST or rlog for ordinations?
DESeq2 medianofratiostransformation StatisticalMethod Normalization dispersion
2.1 years ago Linton • 0
1
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2
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1.4k
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How to perform longitudinal analysis using EdgeR
StatisticalMethod FoldChange edgeR RNASeq
2.1 years ago Sabiha ▴ 20
2
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2
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1.2k
views
DESeq2: Comparison of single clinical sample to 4 normals using tumour cohort to infer dispersion of single sample
GeneExpression DESeq2 RNASeqData RNASeq StatisticalMethod
2.2 years ago Manthos • 0
6
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2
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2.4k
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DecideTest vs topTAGs in edgeR
RNAseq StatisticalMethod edgeR
updated 2.3 years ago by 53k • written 2.3 years ago by ▴ 10
3
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2
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1.3k
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Does this RNAseq experiment require a repeated measures approach?
StatisticalMethod RNASeqData edgeR DESeq2
updated 2.6 years ago by 53k • written 2.6 years ago by ▴ 30
2
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3
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4.0k
views
deseq2 normalization and statistical method
normalization deseq2 StatisticalMethod
updated 2.9 years ago by ★ 5.0k • written 2.9 years ago by ▴ 10
2
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4
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1.3k
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Model comparison in mean-dispersion trend in DESeq2
DESeq2 StatisticalMethod
3.0 years ago Loïc • 0
0
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2
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1.5k
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Using Multi-Dimensional Scaling (MDS) to produce a vector in order to account for patient bias when constructing DGE lists from RNA-seq datasets in R?
PrincipalComponent StatisticalMethod edgeR MultidimensionalScaling Normalization
3.0 years ago rcreswell01 • 0
1
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3
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1.9k
views
Limma-voom with inverse probability weights (similar to sample weights)
limma limma-voom StatisticalMethod
updated 3.0 years ago by 53k • written 3.0 years ago by ▴ 10
0
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1
reply
879
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DESeq2 paired multifactor test
DESeq2 StatisticalMethod
updated 3.2 years ago by 43k • written 3.3 years ago by ▴ 10
0
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0
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1.1k
views
Job: Academic position in Non-clinical Biostatistics
JobPosting StatisticalMethod
3.3 years ago Laurent Gatto 1.6k
1
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2
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1.9k
views
Limma adj.p.value the same for many different p.values
limmaGUI limma adj.p.value StatisticalMethod
3.4 years ago walkerrh95 • 0
0
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0
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1.5k
views
Job: Postdoctoral research scientist in computational biology/statistical genetics/functional genomics at Columbia University, USA
Alzheimer's StatisticalMethod Genetics molecularQTL FunctionalGenomics
3.4 years ago gaow • 0
0
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0
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872
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Should I adjust p value for multi-levels (groups) and multi-variables?
StatisticalMethod
3.9 years ago dong ▴ 10
2
votes
3
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6.8k
views
Differential gene expression and (adjusted) p-values
edgeR StatisticalMethod
updated 3.8 years ago by • 0 • written 4.0 years ago by • 0
6
votes
4
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1.6k
views
Limma prametrization
limm MathematicalBiology limmaGUI StatisticalMethod
4.1 years ago Giovanni • 0
2
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7
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2.3k
views
EdgeR, tumor normal pair, no replicatie but multiple patients, to focus on individual patients not combined
edgeR StatisticalMethod
4.4 years ago Field -Ye • 0
0
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2
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2.3k
views
To retrieve the transcript from gff file with the longest isoform
FunctionalAnnotation StatisticalMethod
4.6 years ago Aneesha • 0
0
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1
reply
1.2k
views
DESeq2 Design matrix
StatisticalMethod DESeq2
updated 4.7 years ago by 43k • written 4.7 years ago by • 0
6
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6
replies
2.7k
views
limma:arrayWeights() and the "prior.n" parameter for biological replicates? (PROTEOMICS)
Proteomics limma StatisticalMethod
updated 4.9 years ago by 53k • written 4.9 years ago by ▴ 10
1
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3
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1.8k
views
How to assign random effect factor in DESeq2 desing?
StatisticalMethod DESeq2 phyloseq
updated 5.0 years ago by 43k • written 5.0 years ago by • 0
0
votes
0
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2.0k
views
Why is `scale-free topology` estimated as -sign(slope) * (R^2) in WGCNA?
Network StatisticalMethod WGCNA ExpressionData
5.1 years ago jol.espinoz ▴ 40
0
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2
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1.1k
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p adjusted value not available
StatisticalMethod DESeq2
updated 5.2 years ago by ★ 4.0k • written 5.2 years ago by • 0
29 results • Page 1 of 1
Recent ...
Replies
Answer: Subsetting data verses contrasts [DESeq2]? by ATpoint ★ 5.0k
This has been asked many times before, please search for relevant posts. In short: Generally it is least tedious to not split the data and …
Comment: Bulk RNAseq analysis for by Mariami • 0
Thank you so much for your help! will try to proceed with the suggestion
Comment: Bulk RNAseq analysis for by Mariami • 0
Thank you for the explanation. I understand, although at the moment we are limited in our ability to increase N. My concern came from the o…
Answer: Bulk RNAseq analysis for by Gordon Smyth 53k
All three packages allow paired comparisons, where the clone is the "pair". limma moreover allows mixed models (just run `voomLmFit` with `…
Answer: Bulk RNAseq analysis for by James W. MacDonald 68k
In my experience, the within-clone variability of differentiated stem cells is often as large or larger than the between-clone variability,…
Votes
Comment: Are transformed values from rlog /vst log2 normalized counts?
Are transformed values from rlog /vst log2 normalized counts?
Answer: Bulk RNAseq analysis for
Answer: DiffBind differential analysis
Answer: Limma-voom sample weights and impact on DEG numbers
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