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Showing :
limma
•
reset
1
vote
2
replies
291
views
Can limma be used with module eigengenes instead of genes?
limma
WGCNA
GSVA
written 12 weeks ago by
A.Barden
▴ 10
0
votes
1
reply
166
views
How to model DE for RNA-seq in concordant monozygotic twins?
RNASeq
variancePartition
RUVSeq
limma
edgeR
updated 4 weeks ago by
Gordon Smyth
53k • written 5 weeks ago by
ilaria.massaiu
• 0
5
votes
13
replies
1.2k
views
Guidance on limma for pseudobulk scRNA-seq with multi-factor design
limma
RNASeq
scRNAseq
updated 6 weeks ago by
Gordon Smyth
53k • written 8 weeks ago by
abaed
• 0
0
votes
4
replies
400
views
voomLmFit fitted log-CPM values
limma
edgeR
updated 9 weeks ago by
Gordon Smyth
53k • written 9 weeks ago by
Lina
▴ 10
1
vote
3
replies
340
views
ROAST compare results with complex design
limma
mroast
roast
CAMERA
written 9 weeks ago by
Jiahao Tian
• 0
2
votes
8
replies
687
views
Are voomByGroup and voomLmFit compatible?
limma
voomLmFit
voomByGroup
updated 9 weeks ago by
Gordon Smyth
53k • written 12 weeks ago by
richardallenfriedmanbrooklyn
▴ 30
3
votes
4
replies
477
views
p-adjusted values in multiple comparisons
StatisticalMethod
limma
RnaSeqSampleSizeData
updated 7 weeks ago by
Josh
• 0 • written 12 weeks ago by
ocanorocabayera
• 0
1
vote
2
replies
336
views
Difference between logFC in limma-voom and weighted limma-voom
limma
voom
weighting
3 months ago
richardallenfriedmanbrooklyn
▴ 30
3
votes
1
reply
322
views
Limpa Pipeline Order
limma
limpa
updated 3 months ago by
Gordon Smyth
53k • written 3 months ago by
abadgerw
• 0
3
votes
2
replies
418
views
Should voomWithQualityWeights still be used when the sample-specific weights vary between the groups of interest?
limma
updated 3 months ago by
Gordon Smyth
53k • written 3 months ago by
A.Barden
▴ 10
0
votes
8
replies
591
views
How to use limma to analyze complex temporal RNAseq data
timecourse
RNASeq
limma
3 months ago
Jiahao Tian
• 0
2
votes
2
replies
389
views
Limma : paired samples leading to unexpected estimates
limma
3 months ago
Basti
▴ 780
2
votes
2
replies
442
views
(Why) do limma's confidence intervals depend on topTable's p.value argument?
limma
3 months ago
sandmann.t
▴ 70
4
votes
8
replies
1.8k
views
Should Xenium pseudobulk experiments be analysed like microarrays (limma) or like RNASeq (edgeR,Deseq2, or limma-voom)
Deseq2
edgeR
limma
xenium
Voom
3 months ago
richardallenfriedmanbrooklyn
▴ 30
7
votes
9
replies
5.6k
views
competitive enrichment test yields too few significant results, self-contained too many
limma
DESeq2
fry
edgeR
4 months ago • updated 3 months ago
bbao
▴ 10
0
votes
1
reply
1.4k
views
How to avoid losing a sample as reference running an individual differential expression analysis (LIMMA)
Microarray
limma
BRAIN
Microarray
limma
BRAIN
updated 4 months ago by
Gordon Smyth
53k • written 16.8 years ago by
Dmitriy Verkhoturov
▴ 10
0
votes
3
replies
2.3k
views
Applying lmFit(), eBayes() and topTable() for modeling associations between NMR-derived metabolic measures and various traits
limma
Bioconductor
Metabolomics
updated 4 months ago by
Gordon Smyth
53k • written 4 months ago by
anni
• 0
0
votes
4
replies
1.7k
views
How to use goana function with zebrafish genome from org.Dr.eg.db
org.Dr.eg.db
zebrafish
limma
4 months ago
Eric
• 0
3
votes
2
replies
6.3k
views
limma duplicateCorrelation appropriate where some blocks cross condition and some are in same condition?
limma
5 months ago
Geoff
• 0
2
votes
3
replies
1.4k
views
Differential gene expression analysis on haplotype-resolved diploid assembly
edgeR
DESeq2
haplotype
limma
5 months ago
Paulito
• 0
0
votes
1
reply
463
views
Typo in the help of lmFit()
limma
updated 5 months ago by
Gordon Smyth
53k • written 5 months ago by
Balazs
• 0
0
votes
2
replies
648
views
Limma suqeezeVar
limma
5 months ago
Mengchun
• 0
0
votes
2
replies
834
views
Limma trend with limpa
limpa
limma
trend
updated 5 months ago by
Gordon Smyth
53k • written 5 months ago by
Alejandro
• 0
2
votes
5
replies
1.2k
views
Dealing with heteroscedascity in limma
limma
splines
Proteomics
written 6 months ago by
Thomas
• 0
5
votes
7
replies
3.3k
views
limma correction for tumor purity
limma
6 months ago
gabriella.jacobson-eisenberg
▴ 20
0
votes
3
replies
961
views
Model performance for spline modelling of RNA-seq timecourses in edgeR
edgeR
limma
written 7 months ago by
skiaphrene
▴ 10
4
votes
7
replies
3.3k
views
Check removeBatchEffect effectiveness
RNAseq
limma
removeBatchEffect
6 months ago • updated 4 weeks ago
massimo
▴ 10
0
votes
0
replies
431
views
Significant Probes and Genes differ in Probe and Region level Differential Methylation Analyses
limma
probe
DMRcate
GenomicRanges
DifferentialMethylation
6 months ago
jamiecatalano2
• 0
2
votes
1
reply
667
views
ROAST for small sets
limma
mroast
updated 6 months ago by
Gordon Smyth
53k • written 6 months ago by
Jiahao Tian
• 0
2
votes
4
replies
1.8k
views
how to use `arrayWeightsQuick()`?
limma
updated 6 months ago by
TraceMorrow
• 0 • written 7 months ago by
matthew
• 0
2
votes
2
replies
1.5k
views
Improving performance of edgeR and limma while adjusting for multiple confounders
edgeR
limma
updated 7 months ago by
ATpoint
★ 5.0k • written 7 months ago by
robinpaul85
• 0
2
votes
4
replies
953
views
Explanation for ROAST results
CAMERA
limma
written 7 months ago by
Jiahao Tian
• 0
5
votes
3
replies
1.2k
views
Using edgeR::voomLmFit for the analysis of paired clinical RNA-seq samples with multiple cell types
edgeR
limma
voomLmFit
updated 7 months ago by
Gordon Smyth
53k • written 7 months ago by
Devin
▴ 10
2
votes
2
replies
1.5k
views
Limma - Complex 2-way multi-level contrast with paired samples
edgeR
contrastmatrix
limma
8 months ago • updated 7 months ago
Elizabeth
• 0
1
vote
2
replies
1.0k
views
Differential expression of proteins using somascan data
somascan
limma
written 8 months ago by
kkeole1
• 0
2
votes
4
replies
1.4k
views
Use of limma R package with targeted proteomics for DE analysis
DEanalysis
limma
olinktargetedproteomics
8 months ago
svlachavas
▴ 840
3
votes
5
replies
2.0k
views
Differential expression of protein coding ENSGs (Ensembl IDs) | When to biomaRt?
limma
edgeR
biomaRt
updated 9 months ago by
James W. MacDonald
68k • written 9 months ago by
Jonathan
▴ 10
0
votes
0
replies
370
views
Testing Differential Expression with Interaction Effect Between Categorical and Continuous Variable with Repeated (Paired) Measures using variancePar…
limma
variancePartition
9 months ago
GJ
• 0
0
votes
2
replies
647
views
Paired analysis in proteomics data for DE while interested in only a particular subset of the data
limma
modelmatrix
pairedanalysis
Proteomics
written 10 months ago by
svlachavas
▴ 840
2
votes
5
replies
772
views
Differential variability modelling with vst() expression
limma
DESeq2
written 10 months ago by
jtsy6383
• 0
6
votes
5
replies
1.1k
views
How do I fix an odd voom plot in a combined dataset?
limma
Normalization
voom
updated 10 months ago by
James W. MacDonald
68k • written 10 months ago by
1sunmic2
• 0
0
votes
2
replies
779
views
Cross-validation with multiple control subgroups in limma
limma
multtest
10 months ago
Ali Barry
▴ 40
1
vote
9
replies
1.5k
views
Normalizing batch effects using technical replicates for DGE analysis between two conditions from 2 different runs
limma
DESeq2
edgeR
written 10 months ago by
anna.cot.anna.cot
▴ 40
0
votes
2
replies
695
views
Advice needed: Using limma for differential pathway analysis with continuous disease progression scores
limma
DifferentialExpression
Designmatrix
11 months ago
Tadeoye
▴ 20
0
votes
2
replies
879
views
sva: get a sv for RIN scores
limma
sva
variancePartition
voom
RNASeq
updated 11 months ago by
Gordon Smyth
53k • written 11 months ago by
Lina
▴ 10
2
votes
3
replies
1.7k
views
How to annotate a limma Elist raw class object with an annotation file
limma
AnnotationDbi
updated 11 months ago by
James W. MacDonald
68k • written 11 months ago by
giulia.gentile
▴ 10
1
vote
2
replies
703
views
contrast matrix design for a continuous variable
limma
11 months ago • updated 9 months ago
dtzhu337
• 0
3
votes
3
replies
1.0k
views
Crossover design with limma
limma
crossover
updated 10 months ago by
Gordon Smyth
53k • written 11 months ago by
Marek Gierlinski
▴ 30
0
votes
9
replies
1.7k
views
Differential Expression Genes as Independent Variables
limma
DifferentialExpression
variancePartition
dream
updated 11 months ago by
James W. MacDonald
68k • written 11 months ago by
abadgerw
• 0
6
votes
10
replies
3.3k
views
What type of counts data to import for performing Isoform analysis in edgeR
limma
isoform
edgeR
salmon
R
updated 11 months ago by
ATpoint
★ 5.0k • written 11 months ago by
mohammedtoufiq91
▴ 10
4,225 results • Page
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Comment: Save the Date: BioC2026
by
eja.gsssssswwse.r.m
• 0
Que notícia incrivel sobre o BioC2026 Para quem gosta de aproveitar o conteudo online, também e possvel Baixar [snaptube versão antiga][1] …
Comment: Ensembl 115 has been released!
by
eja.gsssssswwse.r.m
• 0
Keeping up with Ensembls latest release ensures access to cutting-edge genomic information. For those balancing research and leisure, a mob…
Answer: After running samtools, the featureCounts command crashed.
by
Kevin Blighe
★ 4.0k
Hi Rui Tang, The "buffer overflow detected" error in featureCounts usually stems from a corrupted or malformed GTF file, often due to tr…
Answer: Problem with the TMB plot
by
Kevin Blighe
★ 4.0k
Hi, The linear TMB plot with no clustering suggests your variant calls may lack sample-specific discrimination, likely due to filtering ap…
Answer: gene Set with high AUC score but no cells assigned to cell type
by
Kevin Blighe
★ 4.0k
Hi, You have correctly identified the issue: AUCell's automatic threshold selection is conservative by design, aiming for specificity to…
Votes
Answer: DESeq2 design for haplotype MPRA
Answer: Failure to download resources (MeSHDb) from AnnotationHub
Answer: Failure to download resources (MeSHDb) from AnnotationHub
Answer: Suppress warning in RHDF5 write
Answer: Suppress warning in RHDF5 write
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