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Comment: Making a Full Rank Model for Allele-Specific Expression with DESeq2
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Gordon Smyth
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The design matrix that I described above is completely general. I imagine that it would be possible to use the same approach to generate fu…
Comment: Making a Full Rank Model for Allele-Specific Expression with DESeq2
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chp265
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Cool, glad to hear I wasn't missing some functionality in DESeq2. I don't know that much about the differences between DESeq2 vs edgeR; my …
Comment: Making a Full Rank Model for Allele-Specific Expression with DESeq2
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Michael Love
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Yes, so for one thing, note that Gordon has provided code for doing what you are asking in edgeR, which you can go ahead and use.
You aske…
Comment: Making a Full Rank Model for Allele-Specific Expression with DESeq2
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chp265
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0
I don't think DESeq2 has the ability to do multi-contrast comparisons, at least based on what I can understand of the manual; I can pick mu…
Comment: Upcoming Ensembl API and data access changes - new blog post available
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Thanks for the update. To be very explicit: what is going to happen to the Biomart service, on which the biomaRt bioconductor package relie…
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