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Store Matrix in DataFrame Cell
S4Vectors
10 weeks ago • updated 9 weeks ago
Dario Strbenac
★ 1.6k
0
votes
5
replies
965
views
For some reason I can't update BiocManager to 3.20
Bioconductor
updated 9 weeks ago by
shepherl
4.1k • written 9 weeks ago by
azm.ana2
• 0
0
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0
replies
6
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netresponse
hgu219.db
MantelCorr
IlluminaDataTestFiles
9 weeks ago
Abu
0
0
votes
0
replies
6
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PhenoGeneRanker
BSgenome.Osativa.MSU.MSU7
mouse.db0
SIM
9 weeks ago
Abu
0
0
votes
0
replies
8
views
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Qtlizer
ropls
TransOmicsData
MethylSeekR
9 weeks ago
Abu
0
0
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0
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10
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proDA
org.Sc.sgd.db
TVTB
9 weeks ago
Abu
0
0
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0
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10
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JobPosting
customCMPdb
TransOmicsData
9 weeks ago
Abu
0
0
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0
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12
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GOTHiC
BubbleTree
PANR
9 weeks ago
Abu
0
0
votes
1
reply
260
views
KEGG GSEA using Clusterprofiler - ncbi-geneid missing?
clusterProfiler
KEGG
10 weeks ago
Jessica
• 0
0
votes
0
replies
125
views
News:
GBCC2025 Abstract Submissions & Registration Now Open!
Community
Conference
GBCC2025
Bioconductor
10 weeks ago
Maria Doyle
▴ 100
0
votes
1
reply
186
views
Comparing Mock vs Infected in WT and Knockout Cells
DESeq2
DifferentialExpression
DifferentialRegulation
RNASeq
GeneSetEnrichment
updated 10 weeks ago by
Michael Love
43k • written 10 weeks ago by
Sahil
• 0
0
votes
1
reply
466
views
In WGCNA, what networkType should be used in pickSoftThreshold for a Signed Nowick TomType
WGCNA
pickSoftThreshold
SignedNowick
updated 10 weeks ago by
ATpoint
★ 4.8k • written 11 weeks ago by
ddrummer0056
• 0
0
votes
1
reply
212
views
Error: lexical error: invalid char in json text (alevin-seurat)
tximpo
tximportData
alevinQC
updated 10 weeks ago by
ATpoint
★ 4.8k • written 10 weeks ago by
ptlsugam
• 0
0
votes
0
replies
94
views
Help with MetagenomeSeq, understanding the 75th quantile
metagenomeSeq
cumulativesumscaling
updated 10 weeks ago by
James W. MacDonald
68k • written 10 weeks ago by
boone5jones
• 0
0
votes
0
replies
231
views
Methylation data - different probes are classified differently based on transcript? (Illumina methylation arrays, using minfi)
minf
minfiDataEPIC
MethylationArrayData
MethylationArray
EPICv2manifest
10 weeks ago
charlie.wright
• 0
0
votes
3
replies
567
views
DESeq2 adujsted p-value cutoff seemingly not working
DESeq2
updated 10 weeks ago by
980linnet
• 0 • written 10 weeks ago by
Guilherme
• 0
0
votes
4
replies
499
views
Web accessibility of Bioconductor.org
website
Website
updated 10 weeks ago by
Sean Davis
21k • written 10 weeks ago by
lizhare
• 0
1
vote
2
replies
815
views
Issue with assigning transcript IDs to reads when using summarizeOverlaps(mode = IntersectionNotEmpty)
GenomicAlignments
summarizeOverlaps(
Smart-seq2
proteinvariantcounting
10 weeks ago
SofieK
• 0
0
votes
2
replies
341
views
Meffil: error in functional normalization function (Error in rg.to.mu(rg, probes))
methylationArrayAnalysis
Normalization
Epigenetics
MethylationArrayData
11 weeks ago • updated 10 weeks ago
a.alkema
• 0
0
votes
2
replies
421
views
accounting for vs. removing batch effects with DESeq2 in RNAseq analysis
DESeq2
updated 10 weeks ago by
Blair
• 0 • written 11 weeks ago by
A
• 0
0
votes
3
replies
485
views
displaying the differential expression with deseq2 over 4X2 samples with the individual changes in gene expression per sample
DESeq2
updated 8 weeks ago by
Leonard
• 0 • written 11 weeks ago by
Martijn
• 0
0
votes
3
replies
487
views
How to compare expression levels of genes between scRNAseq and bulkRNAseq?
Seurat
RNASeq
DESeq2
scRNAseq
updated 11 weeks ago by
jodan
• 0 • written 12 weeks ago by
Quang NN
▴ 10
5
votes
5
replies
1.2k
views
Unused arguments error without used arguments in GSVA?
GSVA
updated 28 days ago by
michaelarringtony
• 0 • written 11 weeks ago by
1sunmic2
• 0
0
votes
1
reply
1.1k
views
Using genomicRanges / plyranges to calculate score of peaks within intervals
plyranges
GenomicRanges
updated 11 weeks ago by
Michael Love
43k • written 4.0 years ago by
alorsonmethyle
• 0
1
vote
1
reply
1.7k
views
Reducing and aggregating GRanges with gaps using plyranges
GenomicRanges
plyranges
updated 11 weeks ago by
Michael Love
43k • written 4.5 years ago by
r.a.policastro
• 0
4
votes
3
replies
418
views
plyranges: find exact GRanges match keeping metadata columns
plyranges
updated 10 weeks ago by
Michael Love
43k • written 11 weeks ago by
alexis.weinreb
• 0
0
votes
0
replies
123
views
News:
Mass Spectrometry and Proteomics with R/Bioconductor course
cadd.v1.6.hg38
11 weeks ago
info
▴ 10
0
votes
1
reply
201
views
Restricting differential binding analysis to only TSS-proximal regions
ChIP
csaw
updated 11 weeks ago by
Aaron Lun
★ 28k • written 11 weeks ago by
Luca
• 0
0
votes
0
replies
123
views
Batch Correction while implementing QSEA package
qsea
MEDIPS
MEDIPSData
DNAMethylation
11 weeks ago
User3088
• 0
0
votes
0
replies
113
views
News:
Announcing the GBCC2025 Logo Design Winner!
Community
Conference
GBCC2025
Bioconductor
11 weeks ago
Maria Doyle
▴ 100
0
votes
1
reply
163
views
building samplesheet and plot profile
DiffBind
11 weeks ago
yf
• 0
0
votes
0
replies
87
views
DBT JRF & PhD Scholar
BiologicalQuestion
OmicsMLRepoR
11 weeks ago
Manisha
• 0
0
votes
1
reply
233
views
I am having issues with bowtie2_build
genomes
bowtiew
Index
updated 11 weeks ago by
James W. MacDonald
68k • written 12 weeks ago by
eduardo.pastor
• 0
0
votes
1
reply
278
views
DEG analysis across multiple timepoints, treatments and tissues
DifferentialExpression
RNASeq
DESeq2
updated 11 weeks ago by
Michael Love
43k • written 12 weeks ago by
Sim
• 0
0
votes
0
replies
136
views
My DEXSeqDataSetFromSE is returning an Error, but all of my checks to seem to indicate that this error is not present
DifferentialSplicing
RNASeqData
DEXSeq
12 weeks ago
cftattersfield
• 0
1
vote
0
replies
291
views
News:
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Events
Community
Training
Africa
Bioconductor
12 weeks ago
Maria Doyle
▴ 100
0
votes
2
replies
591
views
How to visualize these pathways using pathview
Salmo_salar
RNASeq
KEGG
pathview
12 weeks ago • updated 9 weeks ago
ingrid.h
• 0
2
votes
2
replies
500
views
Selection of correct coefficients or contrasts in DESeq2
DESeq2
updated 12 weeks ago by
swbarnes2
★ 1.4k • written 12 weeks ago by
Nathan
• 0
9
votes
3
replies
2.2k
views
Job:
Postdoc/RA position: Software Engineer For R and High-Performance Computing
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CuratedAtlasQueryR
tidySpatialExperiment
tidyomics
tidySingleCellExperiment
written 10 months ago by
Stefano Mangiola
▴ 40
0
votes
4
replies
1.0k
views
Why select top highly expressed genes based on normalized counts, but then plot VST-transformed values in DESeq2 pheatmap?
RNASeq
DESeq2
12 weeks ago
Quang NN
▴ 10
1
vote
3
replies
776
views
Csaw normalization strategies - general inquiry
ChIPSeq
csaw
updated 12 weeks ago by
franknappi14
• 0 • written 12 weeks ago by
Luca
• 0
4
votes
9
replies
2.3k
views
Issues with seqlevelsStyle when making custom txdb objects for genomes/annotations from ToxoDB
txdbmaker
GenomeInfoDb
GenomicFeatures
Biostrings
gDNAx
updated 12 weeks ago by
Robert Castelo
★ 3.4k • written 4 months ago by
rohitsatyam102
▴ 20
0
votes
1
reply
257
views
WGCNA sample-data preprocessing order
Microarray
WGCNA
GeneExpression
updated 12 weeks ago by
ATpoint
★ 4.8k • written 3 months ago by
Reuben
• 0
0
votes
2
replies
270
views
WGCNA: Can we use high power (26) for signed network?
Networkanalysis
RNA-seqdata
Powerselection
WGCNA
3 months ago • updated 12 weeks ago
Vinesh
• 0
0
votes
1
reply
164
views
Ph.D. scholar
WGCNA
DataNormalization
MicroarrayData
updated 12 weeks ago by
ATpoint
★ 4.8k • written 12 weeks ago by
Harshul
• 0
0
votes
1
reply
217
views
Unable to find sample sheet file for ChAMP methylation data analysis
MethylationArray
MethylationArrayData
methylationArrayAnalysis
updated 12 weeks ago by
James W. MacDonald
68k • written 3 months ago by
Anki
• 0
0
votes
2
replies
784
views
How to generate circular cnetplot and color nodes and edges in the same plot ?
cnetplot
DESeq2
3 months ago • updated 12 weeks ago
Blandine
• 0
0
votes
5
replies
417
views
Is there a way to do DEG analysis across two batches sharing one sample only?
DESeq2
DifferentialExpression
RNASeqData
BatchEffect
written 3 months ago by
georgeyu703
• 0
0
votes
1
reply
194
views
affymetrix
genomes
Annotation
updated 3 months ago by
James W. MacDonald
68k • written 3 months ago by
aurel.popa2011
• 0
0
votes
1
reply
912
views
Problems with GSEA
GSEABase
updated 3 months ago by
Guido Hooiveld
★ 4.1k • written 3 months ago by
Sidra.Gull
• 0
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Comment: FlowSOM library requires igraph but igraph does not install
by
Szabolcs
• 0
The R/igraph Installation FAQ covers most issues: https://r.igraph.org/articles/installation-troubleshooting.html
Comment: edgeR::cpm() results in negative values from raw counts of 0
by
Kinnary
▴ 20
Thank you very much for the vis suggestion!
Comment: edgeR::cpm() results in negative values from raw counts of 0
by
Kinnary
▴ 20
Thank you very much - I appreciate the mathematical explanation and link to Dr. Phipson's thesis!
Comment: edgeR::cpm() results in negative values from raw counts of 0
by
Kinnary
▴ 20
Thank you very much - this is very clear!
Answer: How do I set up my DESeq analysis when I know a few vehicle control samples prov
by
Michael Love
43k
I think it will capture it automatically. E.g. if you use the method that focuses on genes lowly or not affected by the treatment, then the…
Votes
A: conceptual question about FDR, FDR adjusted p-value and q-value
Comment: edgeR::cpm() results in negative values from raw counts of 0
Comment: edgeR::cpm() results in negative values from raw counts of 0
Answer: edgeR::cpm() results in negative values from raw counts of 0
Answer: edgeR::cpm() results in negative values from raw counts of 0
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