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14 results • Page 1 of 1

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Comment: Weird output of DESeq2 when using single sample from one group agains the other by Michael Love 35k

See the 2014 paper, the MLE LFC is found via IRLS: "We use the standard iteratively reweighted least-squares algorithm [12] for each gene’…

Comment: Weird output of DESeq2 when using single sample from one group agains the other by FantasticAI • 0

Thank you for the help. Sorry for keep asking silly questions: I wonder given 2 groups (A and B), and each group has 6 samples, how does th…

Answer: DESeq2 Responder vs Non-Responders nested design by Michael Love 35k

Unfortunately, I have to reserve my time on the support site for software related questions. For consultation about statistical design and …

Comment: How to use subjunc for differential splicing analysis? by Assa Yeroslaviz ★ 1.5k

I assume, that it would make more sense to quantify the reads based on the gene-level and not the exon-level, following by using the `diffS…

Comment: Reading large file (15GB) in R by nabiyogesh • 0

Thanks Sean, I am getting below error with fread, I am running this on HPC with 500GB. > library(data.table) data.table 1.14.2 u…

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Where can I find EnsDb.Hsapiens.v105?

Two-way interaction, linear redundancy

Answer: Housekeeping genes vary across contrast groups, using DESeq2 on NanoString data

Answer: Joint disperstion estimation for DEXSeq and DESeq2

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