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pairedGSEA input files
pairedGSEA
updated 5 months ago by
shdam
▴ 10 • written 6 months ago by
Sara
• 0
2
votes
5
replies
1.3k
views
Group-specific condition effects with individuals nested: matrix is not full rank
DESeq2
6 months ago
picasa1983
• 0
0
votes
1
reply
305
views
TheProcess got Killed
DSS
updated 6 months ago by
James W. MacDonald
68k • written 6 months ago by
Michael
• 0
3
votes
7
replies
2.3k
views
Vertical line at A=0, nothing else, on MA plot
deseq2
updated 6 months ago by
melissa
▴ 10 • written 6.5 years ago by
david.wheeler7
▴ 20
3
votes
2
replies
658
views
SingleCellExperiment convenience function for metadata+expression?
SpatialExperiment
SingleCellExperiment
SpatialFeatureExperiment
updated 6 months ago by
Stefano Mangiola
▴ 40 • written 8 months ago by
sarah.williams
• 0
1
vote
2
replies
1.8k
views
help documentation for keytypes in annotationdbi packages
annotation
updated 6 months ago by
Eric
▴ 10 • written 4.9 years ago by
kstachelek
• 0
0
votes
1
reply
752
views
How to adjust for Cell Type Differences between groups in Pseudo-Bulk Differential Gene Expression analysis in scRNA-seq?
SingleCellData
DESeq2
pseudobulk
sing
updated 6 months ago by
James W. MacDonald
68k • written 6 months ago by
Sara
• 0
1
vote
1
reply
614
views
Interpreting DESEQ2 interaction term and inclusion of covariate
DESeq2
updated 6 months ago by
swbarnes2
★ 1.4k • written 6 months ago by
Len
▴ 10
0
votes
2
replies
615
views
cameraPR() non directional test
CAMERA
GeneSetEnrichment
6 months ago
Hugo Varet
▴ 80
1
vote
1
reply
409
views
DEseq2 design for additive treatment
DESeq2
updated 6 months ago by
ATpoint
★ 4.9k • written 6 months ago by
picasa1983
• 0
11
votes
6
replies
4.6k
views
WGCNA with paired samples
wgcna
paired samples
exercise
updated 6 months ago by
Ivo
• 0 • written 9.1 years ago by
2323982403
▴ 60
2
votes
2
replies
770
views
Plot title for PCA in DESeq2
DESeq2
6 months ago
AL
• 0
0
votes
0
replies
207
views
Error in convertMSImagingArrays2Experiment / estimateDomain in Cardinal
Mass
Cardinal
6 months ago
Mark Dunning
★ 1.1k
2
votes
4
replies
1.3k
views
Use of limma R package with targeted proteomics for DE analysis
DEanalysis
limma
olinktargetedproteomics
6 months ago
svlachavas
▴ 840
0
votes
1
reply
529
views
Does anyone have the command to download all of the core_nt using blast_db_get()
rBLAST
BiocFileCache
updated 6 months ago by
shepherl
4.2k • written 6 months ago by
Matthew Thornton
▴ 380
1
vote
2
replies
741
views
normalizatino of dna methylation EPIC data
DNA
minfiData
minfiDataEPIC
DNAMethylation
minfi
6 months ago
user_bioinfo
• 0
1
vote
2
replies
1.4k
views
Error in retrieving clinical data
TCGAbiolinks
6 months ago
silickas
• 0
0
votes
0
replies
443
views
News:
EuroBioC2025: Abstract Submissions Open!
EuroBioC2025
Community
Conference
Bioconductor
6 months ago
Maria Doyle
▴ 100
0
votes
6
replies
1.8k
views
News:
EuroBioC2023 abstract submission is open!
presentation
EuroBioC2023
Conference
community
Bioconductor
updated 4 months ago by
eilishhill8
• 0 • written 2.5 years ago by
Maria Doyle
▴ 100
0
votes
1
reply
633
views
News:
Gene Set Enrichment Analysis in Bioconductor course
GSEABase
GeneSetEnrichment
goseq
6 months ago
info
▴ 10
0
votes
1
reply
373
views
Pathview visualisation not including positive log2 fold changes
pathview
Proteomics
updated 6 months ago by
James W. MacDonald
68k • written 6 months ago by
Jessica
• 0
1
vote
0
replies
1.7k
views
Suggesting changing the "reply-to" field to the mailing list address.
updated 6 months ago by
shepherl
4.2k • written 16.1 years ago by
Peng Yu
▴ 950
0
votes
3
replies
835
views
Differential variance analysis - can i use deseq2
DESeq2
DifferentialExpression
RNASeq
RNASeqData
scRNAseq
updated 6 months ago by
Michael Love
43k • written 6 months ago by
Marwan
• 0
1
vote
1
reply
595
views
UniProt.ws query for single UniRef90 ID takes several minutes
UniProt.ws
updated 6 months ago by
James W. MacDonald
68k • written 7 months ago by
Nina
• 0
0
votes
3
replies
601
views
batch effect removal for agilent microarray data
"
"Bioconductor"
Bioconductor
6 months ago
gaye.yilmaz
• 0
0
votes
2
replies
1.1k
views
Automatically install dependencies
Install
dependencies
biocmanager
updated 6 months ago by
shepherl
4.2k • written 7 months ago by
jessica.gillespie
• 0
0
votes
2
replies
1.1k
views
Spam:
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updated 7 months ago by
xihaxiw582
• 0 • written 17.7 years ago by
Allison Hoskins
10
2
votes
2
replies
948
views
SingleR with multiple single cell references
SingleR
scran
7 months ago • updated 5 months ago
maltethodberg
▴ 180
0
votes
0
replies
279
views
Help with mouse cell type annotation
annotation
SingleR
mouse
SingleCellData
scRNAseq
7 months ago
Muhammad
• 0
0
votes
1
reply
869
views
To count or not to count multi-overlapping reads?
RNA-Seq
featureCounts
Rsubread
updated 7 months ago by
Gordon Smyth
53k • written 7 months ago by
Arindam
▴ 80
0
votes
0
replies
181
views
Unable to restore chromosome sequence lengths or other metadata in BSgenome.Mfascicularis.NCBI.6.0
BSgenome.Mfascicularis.NCBI.6.0
7 months ago
Genevieve
• 0
1
vote
2
replies
1.3k
views
Weird p-values using DESeq2?
DESeq2
RNASeq
updated 7 months ago by
ATpoint
★ 4.9k • written 7 months ago by
ingrid.h
• 0
0
votes
0
replies
414
views
Job:
Research Software Engineer - Bioconductor tools for biological data science and AI
Bioconductor
7 months ago
Wolfgang Huber
★ 13k
0
votes
0
replies
168
views
Generating Biphasic Curves in Offline GR Metrics Package
GRmetrics
7 months ago
Jasmitha
• 0
3
votes
5
replies
1.4k
views
Overcoming confounding in batch effect correction
sva
BiologicalQuestion
7 months ago
bbao
▴ 10
3
votes
2
replies
1.1k
views
Store Matrix in DataFrame Cell
S4Vectors
7 months ago
Dario Strbenac
★ 1.6k
0
votes
5
replies
1.6k
views
For some reason I can't update BiocManager to 3.20
Bioconductor
updated 6 months ago by
shepherl
4.2k • written 7 months ago by
azm.ana2
• 0
0
votes
0
replies
6
views
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netresponse
hgu219.db
MantelCorr
IlluminaDataTestFiles
7 months ago
Abu
0
0
votes
0
replies
6
views
Spam:
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PhenoGeneRanker
BSgenome.Osativa.MSU.MSU7
mouse.db0
SIM
7 months ago
Abu
0
0
votes
0
replies
8
views
Spam:
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Qtlizer
ropls
TransOmicsData
MethylSeekR
7 months ago
Abu
0
0
votes
0
replies
10
views
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proDA
org.Sc.sgd.db
TVTB
7 months ago
Abu
0
0
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0
replies
10
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JobPosting
customCMPdb
TransOmicsData
7 months ago
Abu
0
0
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0
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12
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Spam:
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GOTHiC
BubbleTree
PANR
7 months ago
Abu
0
0
votes
1
reply
683
views
KEGG GSEA using Clusterprofiler - ncbi-geneid missing?
clusterProfiler
KEGG
7 months ago
Jessica
• 0
0
votes
0
replies
332
views
News:
GBCC2025 Abstract Submissions & Registration Now Open!
Community
Conference
GBCC2025
Bioconductor
7 months ago
Maria Doyle
▴ 100
0
votes
1
reply
331
views
Comparing Mock vs Infected in WT and Knockout Cells
DESeq2
DifferentialExpression
DifferentialRegulation
RNASeq
GeneSetEnrichment
updated 7 months ago by
Michael Love
43k • written 7 months ago by
Sahil
• 0
0
votes
1
reply
690
views
In WGCNA, what networkType should be used in pickSoftThreshold for a Signed Nowick TomType
WGCNA
pickSoftThreshold
SignedNowick
updated 7 months ago by
ATpoint
★ 4.9k • written 7 months ago by
ddrummer0056
• 0
0
votes
1
reply
374
views
Error: lexical error: invalid char in json text (alevin-seurat)
tximpo
tximportData
alevinQC
updated 7 months ago by
ATpoint
★ 4.9k • written 7 months ago by
ptlsugam
• 0
0
votes
0
replies
165
views
Help with MetagenomeSeq, understanding the 75th quantile
metagenomeSeq
cumulativesumscaling
updated 7 months ago by
James W. MacDonald
68k • written 7 months ago by
boone5jones
• 0
0
votes
0
replies
313
views
Methylation data - different probes are classified differently based on transcript? (Illumina methylation arrays, using minfi)
minf
minfiDataEPIC
MethylationArrayData
MethylationArray
EPICv2manifest
7 months ago
charlie.wright
• 0
46,625 results • Page
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Comment: Guidance on limma for pseudobulk scRNA-seq with multi-factor design
by
Gordon Smyth
53k
Normalization or filtering are never done for subsets of samples in any limma or edgeR analysis. These things must always be done globally.
Answer: DESeq2 interactions
by
swbarnes2
★ 1.4k
The simpler way to do the first four comparisons is to make a new column in colData that is temp_pollution, and specify that column alone a…
Comment: How to construct a BSgenome object from a custom genome assembly using BSgenomeF
by
James W. MacDonald
68k
You are. The reason I pointed you to `forgeBSgenomeDataPkgFromTwobitFile` is because it's much simpler, doesn't require a seed file, and is…
Comment: How to construct a BSgenome object from a custom genome assembly using BSgenomeF
by
mat149
▴ 80
I've tried the following, but I must be missing something: setwd("C:\\Users\\....\\wd\\dump\\seqs_srcdir") e122<-readDNA…
Comment: readBam vs read_bam_insert_metrics
by
rtrivedi1
▴ 10
Thanks for the answer.
Votes
Comment: How to construct a BSgenome object from a custom genome assembly using BSgenomeF
Answer: Guidance on limma for pseudobulk scRNA-seq with multi-factor design
Answer: How to left_join a tidySummarizedExperiment with a GRanges object by seqnames an
Answer: Limpa Pipeline Order
A: How barcode-plot enrichment is calculated?
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