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I want my overlapping peaks to stop merging by default doing read counting (using DiffBind in R-studio)
peakoverlap
mergingpeaks
ChIPseq
DiffBind
5 hours ago
atlanta
• 0
0
votes
1
reply
81
views
PhD scholar
RNASeqAnalysis
DESeq2
updated 1 hour ago by
shepherl
4.1k • written 8 hours ago by
Richa
• 0
0
votes
3
replies
332
views
how to use `arrayWeightsQuick()`?
limma
updated 6 hours ago by
Gordon Smyth
52k • written 1 day ago by
matthew
• 0
0
votes
0
replies
26
views
Comparison of results obtained from a subset of the data versus the complete dataset for a few selected genes.
DESeq2
18 hours ago • updated 17 hours ago
Bioinformatician_R
▴ 20
0
votes
1
reply
100
views
Differential expression analysis using two TCGA datasets
DifferentialExpression
TCGAbiolinks
RNASeq
updated 5 hours ago by
ATpoint
★ 4.8k • written 18 hours ago by
Shaimaa Gamal
• 0
1
vote
4
replies
609
views
fast apply on RleList
GenomicRanges
RleList
1 day ago • updated 19 hours ago
story.benjamin
▴ 20
0
votes
1
reply
166
views
Custom CDF creation for HTA 2.0 array using GTF annotation
oligo
oligoClasses
pdInfoBuilder
affycoretools
affyio
1 day ago • updated 5 hours ago
Seymoo
• 0
0
votes
8
replies
1.4k
views
Deleted:No significant MVPs with a BH adjusted P-value below 0.05
ChAMP
written 16 months ago by
486342583
• 0
3
votes
5
replies
676
views
BiocParallel_1.40.1.tar.gz not available
BiocParallel
2 days ago • updated 1 day ago
Johan
• 0
1
vote
0
replies
326
views
Modelling gene program dynamics across time with {lemur}
lemur
1 day ago • updated just now
BiotechPedro
▴ 10
1
vote
7
replies
2.3k
views
DNAStringSet(x, start=, end=) loses quality information
Biostrings
updated 1 day ago by
stenlana035
• 0 • written 3.3 years ago by
Gerhard Thallinger
▴ 180
0
votes
0
replies
32
views
Intepretation of results
AUCell
2 days ago
jasperwong_123
• 0
0
votes
2
replies
378
views
Model performance for spline modelling of RNA-seq timecourses in edgeR
edgeR
limma
3 days ago • updated 1 day ago
skiaphrene
▴ 10
0
votes
1
reply
226
views
DESeq2 - am I extracting results incorrectly?
DESeq2
updated 2 days ago by
James W. MacDonald
68k • written 3 days ago by
bd2000
▴ 30
0
votes
0
replies
43
views
WGCNA
WGCNA
DESeq2
3 days ago
bioinformaticssrm2011
• 0
2
votes
1
reply
245
views
Having Trouble Using CNE12() and CNE21() in CNEr
GenomicRanges
CNEr
3 days ago
1324087964
• 0
0
votes
1
reply
285
views
Origin of the labels for the SingleCellMultiModal dataset
labels
PBMC
SingleCellMultiModal
10X
updated 3 days ago by
ATpoint
★ 4.8k • written 3 days ago by
javier.ruizramirez
• 0
0
votes
1
reply
263
views
DiffBind can't find a DAR
dar
ATACSeq
DiffBind
updated 3 days ago by
ATpoint
★ 4.8k • written 3 days ago by
Mengjun
• 0
1
vote
3
replies
722
views
DESeq - help with pair wise comparisons
DESeq2
4 days ago • updated 3 days ago
bd2000
▴ 30
0
votes
0
replies
25
views
Spam:
Looking for Josey Wales Jacket?
MethylSeekR
6 days ago
Shoqz
0
0
votes
0
replies
103
views
Differing results with DESeq2
DESeq2
6 days ago • updated 2 days ago
hampsdiv
• 0
1
vote
8
replies
2.4k
views
DESeq: Gene is not flagged as differentially expressed despite count data showing differences
DifferentialExpression
DESeq2
7 days ago • updated 3 days ago
ktz
• 0
0
votes
2
replies
676
views
compute_fasta_digest does not match Salmon index hash
tximeta
16 days ago • updated 7 days ago
Alex
• 0
0
votes
0
replies
52
views
News:
Introduction to Epigenomics data analysis with R and Bioconductor course (online) - 14th-18th April
chipseq
MNaseSeq
ATACSeq
8 days ago • updated 4 days ago
info
▴ 10
1
vote
2
replies
818
views
Gene IDs conversion between Ensembl and NCBI nomenclature for non-model species
annotation
geneIDs
flatheadmullet
updated 8 days ago by
James W. MacDonald
68k • written 8 days ago by
andremicc
• 0
0
votes
1
reply
423
views
News:
List of Deprecated Packages for Bioc3.20
Release
Devel
Bioconductor
5 months ago • updated 8 days ago
shepherl
4.1k
0
votes
1
reply
121
views
Issue with Soft-Thresholding in WGCNA
WGCNA
updated 8 days ago by
dirty.cougar.risi
• 0 • written 9 days ago by
Μαρία
• 0
0
votes
0
replies
18
views
Spam:
Experience lasting confidence with Vidalista 40 mg
org.Sc.sgd.db
10 days ago
irenejoshi07
0
1
vote
2
replies
1.1k
views
Help with the code for "BiocNeighbors::generic_find_knn() function used by scran::quickCluster()
BiocNeighbors
generic_find_knn
scran
quickCluster
12 days ago • updated 11 days ago
Arctic
• 0
0
votes
1
reply
527
views
DESeq2
org.Mmu.eg.db
DESeq2
TimeCourse
DMSOvsdrug
RNASeqData
updated 12 days ago by
ATpoint
★ 4.8k • written 13 days ago by
Cosmic
• 0
0
votes
1
reply
518
views
Mismatch between Illumina Mouse Methylation BeadChip annotation and genome browsers (UCSC/Ensembl)
methylationArrayAnalysis
MethylationArrayData
updated 13 days ago by
James W. MacDonald
68k • written 14 days ago by
luisa.turco
• 0
1
vote
4
replies
1.4k
views
Package developing and interoperation with Bioconductor
Package
Bioconductor
14 days ago • updated 13 days ago
slizchap
• 0
4
votes
6
replies
1.2k
views
Surprising behavior for DEXseq dispersion estimate plot?
DESeq2
DEXSeq
updated 14 days ago by
ATpoint
★ 4.8k • written 5 weeks ago by
Elijah
• 0
0
votes
4
replies
1.1k
views
Error in H5Dclose(h5dataset) when trying to read in kallisto h5 files
tximport
rhdf5
14 days ago • updated 10 days ago
Sofia
• 0
1
vote
1
reply
750
views
ComBat with repeated measures
ComBat
sva
updated 14 days ago by
ATpoint
★ 4.8k • written 14 days ago by
s20
• 0
0
votes
0
replies
64
views
News:
List of Deprecated Packages for Bioc3.21
devel
Release
release
Devel
14 days ago
shepherl
4.1k
0
votes
0
replies
70
views
News:
Bioconductor 3.21 Release Schedule Important Deadlines Approaching
Software
Release
release
14 days ago
shepherl
4.1k
0
votes
0
replies
64
views
Correlation threshold
MethylationArray
methylationArrayAnalysis
StatisticalMethod
16 days ago
user_bioinfo
• 0
0
votes
0
replies
4
views
Spam:
Does Spirit give free refunds?
ncdfFlow
hcg110.db
MethylSeekR
16 days ago
Haggu
10
0
votes
0
replies
28
views
Spam:
Can I change my BA flight to another date?
org.Sc.sgd.db
MafDb.1Kgenomes.phase1.GRCh38
ncdfFlow
16 days ago
Haggu
10
1
vote
0
replies
22
views
Spam:
What is the cheapest day to fly on American Airlines? {Ask_Expert}
cadd.v1.6.hg38
MafDb.1Kgenomes.phase1.GRCh38
ncdfFlow
16 days ago
Haggu
10
0
votes
0
replies
41
views
Spam:
Can I cancel my British Airways flight and get a refund?
CAGEr
gep2pep
hcg110.db
16 days ago
Haggu
10
0
votes
0
replies
8
views
Spam:
vjkftykdtyk
proDA
hcg110.db
zlibbioc
16 days ago
Haggu
10
2
votes
2
replies
1.2k
views
Improving performance of edgeR and limma while adjusting for multiple confounders
edgeR
limma
updated 16 days ago by
ATpoint
★ 4.8k • written 16 days ago by
robinpaul85
• 0
0
votes
2
replies
417
views
Merging EPICV1 and V2 betas
minfiDataEPIC
minfi
updated 14 days ago by
Garbayo
• 0 • written 16 days ago by
rania.alanany
• 0
0
votes
1
reply
207
views
Error in cnetplot
enrichplot
clusterProfiler
updated 16 days ago by
Guido Hooiveld
★ 4.1k • written 22 days ago by
Ayesha
• 0
0
votes
3
replies
504
views
getBM from biomaRt inconsistencies found with .gtf files across multiple species
.gtf
biomaRt
Ensembl
updated 16 days ago by
Mike Smith
★ 6.6k • written 16 days ago by
Benjamin
▴ 20
2
votes
3
replies
663
views
Explanation for ROAST results
CAMERA
limma
updated 16 days ago by
Gordon Smyth
52k • written 16 days ago by
Jay
• 0
0
votes
0
replies
267
views
How do I set up my DESeq analysis when I know a few vehicle control samples provide background effects we don't want to see in any of the subsequent …
DESeq2
RUVSeq
16 days ago
Simran
• 0
1
vote
1
reply
163
views
Merging annotation with differential expression output
annotation
RNASeqData
updated 16 days ago by
James W. MacDonald
68k • written 17 days ago by
AL
• 0
46,451 results • Page
1 of 930
Recent ...
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Comment: Differential expression analysis using two TCGA datasets
by
ATpoint
★ 4.8k
If these are two different batches then they're fully confounded making it statistically invalid. Biologically, I find it at least question…
Comment: PhD scholar
by
ATpoint
★ 4.8k
Hi, please consider asking this at biostars.org as here we're mainly answering precise technical questions towards the packages. You are se…
Answer: how to use `arrayWeightsQuick()`?
by
Gordon Smyth
52k
Yes, that is the correct way to use `arrayWeightsQuick`. Thanks for pointing out that there is still a reference to `arrayWeightsSimple` i…
Answer: fast apply on RleList
by
story.benjamin
▴ 20
solved with viewApply (code is simplified below) + map reduce on chrs test.split <- split(test.gr,seqnames(test.gr)) final.st…
Comment: fast apply on RleList
by
story.benjamin
▴ 20
Hi James, thanks for the reply. I ultimately figured it out ... viewApply showed a massive speed increase for me (see other answer) - I was…
Votes
Having Trouble Using CNE12() and CNE21() in CNEr
Answer: Having Trouble Using CNE12() and CNE21() in CNEr
annotation EpicV2
Answer: fast apply on RleList
Answer: BiocParallel_1.40.1.tar.gz not available
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