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Comparison of results obtained from a subset of the data versus the complete dataset for a few selected genes.
DESeq2
3 hours ago
Bioinformatician_R
▴ 20
0
votes
0
replies
11
views
Differential expression analysis using two TCGA datasets
DifferentialExpression
TCGAbiolinks
RNASeq
4 hours ago
Shaimaa Gamal
• 0
1
vote
4
replies
320
views
fast apply on RleList
GenomicRanges
RleList
1 day ago • updated 5 hours ago
story.benjamin
▴ 20
0
votes
1
reply
97
views
Custom CDF creation for HTA 2.0 array using GTF annotation
oligo
oligoClasses
pdInfoBuilder
affycoretools
affyio
updated 6 hours ago by
James W. MacDonald
68k • written 13 hours ago by
Seymoo
• 0
0
votes
8
replies
1.4k
views
Deleted:No significant MVPs with a BH adjusted P-value below 0.05
ChAMP
written 16 months ago by
486342583
• 0
0
votes
2
replies
204
views
how to use `arrayWeightsQuick()`?
limma
1 day ago • updated 7 hours ago
matthew
• 0
3
votes
5
replies
588
views
BiocParallel_1.40.1.tar.gz not available
BiocParallel
1 day ago • updated 10 hours ago
Johan
• 0
1
vote
0
replies
273
views
Modelling gene program dynamics across time with {lemur}
lemur
1 day ago
BiotechPedro
▴ 10
1
vote
7
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2.3k
views
DNAStringSet(x, start=, end=) loses quality information
Biostrings
updated 19 hours ago by
stenlana035
• 0 • written 3.3 years ago by
Gerhard Thallinger
▴ 180
0
votes
0
replies
31
views
Intepretation of results
AUCell
1 day ago
jasperwong_123
• 0
0
votes
2
replies
375
views
Model performance for spline modelling of RNA-seq timecourses in edgeR
edgeR
limma
2 days ago • updated 14 hours ago
skiaphrene
▴ 10
0
votes
1
reply
223
views
DESeq2 - am I extracting results incorrectly?
DESeq2
updated 2 days ago by
James W. MacDonald
68k • written 2 days ago by
bd2000
▴ 30
0
votes
0
replies
39
views
WGCNA
WGCNA
DESeq2
2 days ago
bioinformaticssrm2011
• 0
0
votes
1
reply
154
views
Having Trouble Using CNE12() and CNE21() in CNEr
GenomicRanges
CNEr
2 days ago
1324087964
• 0
0
votes
1
reply
280
views
Origin of the labels for the SingleCellMultiModal dataset
labels
PBMC
SingleCellMultiModal
10X
updated 2 days ago by
ATpoint
★ 4.8k • written 3 days ago by
javier.ruizramirez
• 0
0
votes
1
reply
262
views
DiffBind can't find a DAR
dar
ATACSeq
DiffBind
updated 3 days ago by
ATpoint
★ 4.8k • written 3 days ago by
Mengjun
• 0
1
vote
3
replies
719
views
DESeq - help with pair wise comparisons
DESeq2
3 days ago
bd2000
▴ 30
0
votes
0
replies
25
views
Spam:
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MethylSeekR
5 days ago
Shoqz
0
0
votes
0
replies
101
views
Differing results with DESeq2
DESeq2
6 days ago • updated 1 day ago
hampsdiv
• 0
1
vote
8
replies
2.4k
views
DESeq: Gene is not flagged as differentially expressed despite count data showing differences
DifferentialExpression
DESeq2
6 days ago • updated 3 days ago
ktz
• 0
0
votes
2
replies
671
views
compute_fasta_digest does not match Salmon index hash
tximeta
16 days ago • updated 6 days ago
Alex
• 0
0
votes
0
replies
48
views
News:
Introduction to Epigenomics data analysis with R and Bioconductor course (online) - 14th-18th April
chipseq
MNaseSeq
ATACSeq
7 days ago • updated 3 days ago
info
▴ 10
1
vote
2
replies
815
views
Gene IDs conversion between Ensembl and NCBI nomenclature for non-model species
annotation
geneIDs
flatheadmullet
updated 8 days ago by
James W. MacDonald
68k • written 8 days ago by
andremicc
• 0
0
votes
1
reply
423
views
News:
List of Deprecated Packages for Bioc3.20
Release
Devel
Bioconductor
5 months ago • updated 8 days ago
shepherl
4.1k
0
votes
1
reply
118
views
Issue with Soft-Thresholding in WGCNA
WGCNA
updated 7 days ago by
dirty.cougar.risi
• 0 • written 8 days ago by
Μαρία
• 0
0
votes
0
replies
18
views
Spam:
Experience lasting confidence with Vidalista 40 mg
org.Sc.sgd.db
9 days ago
irenejoshi07
0
1
vote
2
replies
1.1k
views
Help with the code for "BiocNeighbors::generic_find_knn() function used by scran::quickCluster()
BiocNeighbors
generic_find_knn
scran
quickCluster
11 days ago
Arctic
• 0
0
votes
1
reply
527
views
DESeq2
org.Mmu.eg.db
DESeq2
TimeCourse
DMSOvsdrug
RNASeqData
updated 12 days ago by
ATpoint
★ 4.8k • written 12 days ago by
Cosmic
• 0
0
votes
1
reply
515
views
Mismatch between Illumina Mouse Methylation BeadChip annotation and genome browsers (UCSC/Ensembl)
methylationArrayAnalysis
MethylationArrayData
updated 13 days ago by
James W. MacDonald
68k • written 13 days ago by
luisa.turco
• 0
1
vote
4
replies
1.4k
views
Package developing and interoperation with Bioconductor
Package
Bioconductor
14 days ago • updated 13 days ago
slizchap
• 0
4
votes
6
replies
1.2k
views
Surprising behavior for DEXseq dispersion estimate plot?
DESeq2
DEXSeq
updated 13 days ago by
ATpoint
★ 4.8k • written 5 weeks ago by
Elijah
• 0
0
votes
4
replies
1.1k
views
Error in H5Dclose(h5dataset) when trying to read in kallisto h5 files
tximport
rhdf5
14 days ago • updated 9 days ago
Sofia
• 0
1
vote
1
reply
750
views
ComBat with repeated measures
ComBat
sva
updated 13 days ago by
ATpoint
★ 4.8k • written 14 days ago by
s20
• 0
0
votes
0
replies
63
views
News:
List of Deprecated Packages for Bioc3.21
devel
Release
release
Devel
14 days ago
shepherl
4.1k
0
votes
0
replies
66
views
News:
Bioconductor 3.21 Release Schedule Important Deadlines Approaching
Software
Release
release
14 days ago
shepherl
4.1k
0
votes
0
replies
64
views
Correlation threshold
MethylationArray
methylationArrayAnalysis
StatisticalMethod
15 days ago
user_bioinfo
• 0
0
votes
0
replies
4
views
Spam:
Does Spirit give free refunds?
ncdfFlow
hcg110.db
MethylSeekR
15 days ago
Haggu
10
0
votes
0
replies
28
views
Spam:
Can I change my BA flight to another date?
org.Sc.sgd.db
MafDb.1Kgenomes.phase1.GRCh38
ncdfFlow
15 days ago
Haggu
10
1
vote
0
replies
22
views
Spam:
What is the cheapest day to fly on American Airlines? {Ask_Expert}
cadd.v1.6.hg38
MafDb.1Kgenomes.phase1.GRCh38
ncdfFlow
15 days ago
Haggu
10
0
votes
0
replies
41
views
Spam:
Can I cancel my British Airways flight and get a refund?
CAGEr
gep2pep
hcg110.db
15 days ago
Haggu
10
0
votes
0
replies
8
views
Spam:
vjkftykdtyk
proDA
hcg110.db
zlibbioc
15 days ago
Haggu
10
2
votes
2
replies
1.2k
views
Improving performance of edgeR and limma while adjusting for multiple confounders
edgeR
limma
updated 15 days ago by
ATpoint
★ 4.8k • written 16 days ago by
robinpaul85
• 0
0
votes
2
replies
417
views
Merging EPICV1 and V2 betas
minfiDataEPIC
minfi
updated 13 days ago by
Garbayo
• 0 • written 16 days ago by
rania.alanany
• 0
0
votes
1
reply
200
views
Error in cnetplot
enrichplot
clusterProfiler
updated 16 days ago by
Guido Hooiveld
★ 4.1k • written 22 days ago by
Ayesha
• 0
0
votes
3
replies
503
views
getBM from biomaRt inconsistencies found with .gtf files across multiple species
.gtf
biomaRt
Ensembl
updated 15 days ago by
Mike Smith
★ 6.6k • written 16 days ago by
Benjamin
▴ 20
2
votes
3
replies
663
views
Explanation for ROAST results
CAMERA
limma
updated 15 days ago by
Gordon Smyth
52k • written 16 days ago by
Jay
• 0
0
votes
0
replies
259
views
How do I set up my DESeq analysis when I know a few vehicle control samples provide background effects we don't want to see in any of the subsequent …
DESeq2
RUVSeq
16 days ago
Simran
• 0
1
vote
1
reply
163
views
Merging annotation with differential expression output
annotation
RNASeqData
updated 16 days ago by
James W. MacDonald
68k • written 16 days ago by
AL
• 0
0
votes
2
replies
379
views
Annotation package for Manduca sexta
annotation
Manducasexta
AnnotationData
16 days ago • updated 15 days ago
GA
▴ 10
0
votes
5
replies
295
views
Bioconductor unable to update 'curl'
curl
HELP
17 days ago
kagodwi2
• 0
46,449 results • Page
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Answer: fast apply on RleList
by
story.benjamin
▴ 20
solved with viewApply (code is simplified below) + map reduce on chrs test.split <- split(test.gr,seqnames(test.gr)) final.st…
Comment: fast apply on RleList
by
story.benjamin
▴ 20
Hi James, thanks for the reply. I ultimately figured it out ... viewApply showed a massive speed increase for me (see other answer) - I was…
Answer: fast apply on RleList
by
James W. MacDonald
68k
There is already a 'mean' function that will dispatch on an `RleList` that you can use. I don't have a long `RleList` in hand to test it on…
Answer: Custom CDF creation for HTA 2.0 array using GTF annotation
by
James W. MacDonald
68k
It doesn't appear that Manhong Dai is working at UM any longer, and the webpage appears to have fallen into disrepair (for example, the lin…
Comment: how to use `arrayWeightsQuick()`?
by
matthew
• 0
In the specific use-case I have in mind, `expression` is a simple `matrix` of log2 gene expression per sample, no missing values.
Votes
annotation EpicV2
Answer: fast apply on RleList
Answer: BiocParallel_1.40.1.tar.gz not available
Modelling gene program dynamics across time with {lemur}
A: DESeq2 one group vs multiple groups comparison in presence of batch effect
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