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Showing :
Limma
•
reset
2
votes
2
replies
1.2k
views
Using limma for controlling age variable
linearmodeling
limma
21 months ago
Matej
• 0
4
votes
6
replies
1.6k
views
filtering lowly expressed reads
RNASeq
limma
DifferentialExpression
Preprocessing
updated 21 months ago by
Gordon Smyth
53k • written 22 months ago by
Shaimaa Gamal
• 0
0
votes
5
replies
1.9k
views
Can SVs identified from sva be used for removeBatchEffect() in DESeq2
sva
DESeq2
BatchEffect
limma
updated 22 months ago by
ATpoint
★ 5.0k • written 22 months ago by
Xiao
• 0
2
votes
4
replies
1.2k
views
Different genes expression with limma
DESeq2
DifferentialExpression
limma
updated 22 months ago by
Gordon Smyth
53k • written 23 months ago by
michelafrancesconi8
• 0
1
vote
2
replies
822
views
Assess fit of variance prior
limma
updated 23 months ago by
Gordon Smyth
53k • written 23 months ago by
Frederik Ziebell
▴ 30
2
votes
1
reply
625
views
removeBatchEffect with non-linear model fit
limma
DESeq2
updated 23 months ago by
Gordon Smyth
53k • written 23 months ago by
georgii.vdovin
• 0
2
votes
4
replies
1.8k
views
Correct the batch effect in methylation analysis in R
BatchEffect
limma
methylationArrayAnalysis
updated 23 months ago by
Gordon Smyth
53k • written 23 months ago by
kyj2226
• 0
0
votes
3
replies
880
views
Agilent Microarray Gene Oncology analysis gone wrong
AgilentChip
limma
goana
updated 23 months ago by
SamGG
▴ 360 • written 23 months ago by
samagbeyimodupe
• 0
5
votes
2
replies
1.5k
views
Filter genes by expression for voomLmFit
DEG
edgeR
limma
voom
filterByExpr
updated 23 months ago by
Gordon Smyth
53k • written 23 months ago by
annikagable
• 0
12
votes
5
replies
5.0k
views
limma::voom vs edgeR::voomLmFit - when to use?
edgeR
limma
voom
RNASeq
muscat
updated 5 months ago by
Geoff
• 0 • written 23 months ago by
annikagable
• 0
0
votes
0
replies
689
views
multipollutant models
statistics
Regression
r
limma
23 months ago
Jitendra
▴ 10
0
votes
3
replies
1.3k
views
'Subtracting' counts on basis of Negative control media and water samples
limma
edgeR
RNASeq
DESeq2
23 months ago
Karthik
• 0
1
vote
1
reply
721
views
Limma/DESeq2 for unbalanced nested design (paired samples)
limma
DESeq2
updated 23 months ago by
Michael Love
43k • written 23 months ago by
michael.eigenschink
• 0
3
votes
4
replies
1.4k
views
Is it appropriate to apply linear mixed models to Voom transformed data?
stats
r
RNASeqData
limma
voom
23 months ago
pl23
• 0
2
votes
4
replies
1.4k
views
limma + voom combine voomWithQualityWeights and duplicateCorrelation
voom
RNASeq
limma
24 months ago
Tyler Sagendorf
▴ 10
1
vote
4
replies
1.5k
views
controling for batch effect while preserving variation within repeated measures that unevenly distributed across batches
miRNA
BatchEffect
RNASeq
limma
2.0 years ago
Wending
• 0
0
votes
4
replies
1.4k
views
How to correct for known and surrogate variables in DESeq2?
DESeq2
BatchEffect
sva
limma
updated 19 months ago by
Michael Love
43k • written 2.0 years ago by
Crystal571
• 0
0
votes
5
replies
1.4k
views
Limma continuous design (association polygenic risk score with gene expression)
limma
updated 23 months ago by
Gordon Smyth
53k • written 2.0 years ago by
e.vanzanten.1
• 0
0
votes
5
replies
1.8k
views
minfi, limma, adjusting for cell counts - integrating the resoults of estimateCellCounts into the linear regression model
minfi
limma
2.1 years ago
dorota.komar
• 0
0
votes
1
reply
808
views
Issue with weights in voomLmFit()
limma
updated 12 months ago by
Gordon Smyth
53k • written 2.1 years ago by
gabriel.hoffman
▴ 170
2
votes
1
reply
1.5k
views
limma::topTable with adjust.method=NULL is not BH corrected (manual is inconsistent with behavior?)
Bioconductor
biocon
limma
updated 2.1 years ago by
Gordon Smyth
53k • written 2.1 years ago by
ningyuan
• 0
1
vote
7
replies
1.8k
views
DuplicateCorrelation() block by duplicate sample or by cell line ?
variancePartition
RNASeqData
limma
BulkRNAseq
RNASeq
updated 23 months ago by
Gordon Smyth
53k • written 2.1 years ago by
Gimena
• 0
5
votes
3
replies
1.2k
views
limma: More differentially expressed genes when factor included in model than when used as blocking factor
voom
blocking
limma
updated 2.1 years ago by
Gordon Smyth
53k • written 2.1 years ago by
Gerhard Thallinger
▴ 180
5
votes
9
replies
2.8k
views
Batch correction and repeated measures
RUVSeq
sva
limma
updated 19 months ago by
Gordon Smyth
53k • written 2.1 years ago by
Jonathan
▴ 10
0
votes
1
reply
821
views
''Model_Matrix'' error
DifferentialExpression
limma
updated 2.1 years ago by
Gordon Smyth
53k • written 2.1 years ago by
Laghalelle
• 0
1
vote
6
replies
3.7k
views
Can I use EdgeR log2(cpm) instead of voom log2(cpm) to be analyzed as microarray data?
limma
edger
timecourse
without replicate
voom
written 9.0 years ago by
Camila Orellana
▴ 10
0
votes
0
replies
558
views
Huge effect of a single sample on DEGs
limma
2.1 years ago
Jonathan
▴ 10
1
vote
1
reply
754
views
Further analysis after limma regression output
statistics
Epigenetics
limma
updated 2.1 years ago by
James W. MacDonald
68k • written 2.1 years ago by
Jitendra
▴ 10
3
votes
3
replies
989
views
comparing contrasts in edger/lima using makeContrasts function
DifferentialExpression
edgeR
limma
updated 2.1 years ago by
James W. MacDonald
68k • written 2.1 years ago by
stuartthafass
• 0
3
votes
3
replies
3.5k
views
Differential expression analysis with only FPKM matrix available from total newbie in R
FPKM
RNASeqData
DEAnalysis
limma
2.1 years ago
Ethan Nguyen
• 0
1
vote
2
replies
2.0k
views
Should I use CPM or Voom transformed values for downstream analysis?
edgeR
limma
2.1 years ago
petertam1343
• 0
0
votes
6
replies
1.5k
views
Help with model.matrix and creating the right contrast matrix for limma
limma
2.2 years ago • updated 23 months ago
rober204
• 0
6
votes
5
replies
13k
views
Using Limma R package For Proteomics differential expression
limma
ProteomicsWorkflow
updated 2.2 years ago by
Gordon Smyth
53k • written 4.0 years ago by
David Lyon
▴ 340
4
votes
5
replies
1.5k
views
Phenotype effect - building a contrast matrix - grouping vs interaction
limma
updated 2.1 years ago by
Gordon Smyth
53k • written 2.2 years ago by
Jonathan
▴ 10
3
votes
13
replies
2.3k
views
Timely differentially expressed genes
timecoursedata
limma
2.2 years ago • updated 23 months ago
triZZla
• 0
0
votes
1
reply
837
views
Is it possible to combine count gene expression data coming from one sequencing technology (RNA seq) with intensity gene expression data coming from …
DESeq2
RNASeqData
edgeR
limma
DifferentialExpression
updated 2.2 years ago by
ATpoint
★ 5.0k • written 2.2 years ago by
Sep
• 0
1
vote
6
replies
1.6k
views
Limma dispersed distribution of log fold change
limma
written 2.2 years ago by
Erin Yu
• 0
1
vote
0
replies
845
views
Differential abundance analysis of phosphoproteomics data with multiple time points and conditions
Proteomics
DifferentialRegulation
limma
2.2 years ago
svlachavas
▴ 840
0
votes
2
replies
882
views
How to incorporate covariate factors into design to analyse a continuous variable?
DifferentialMethylation
limma
written 2.2 years ago by
Diren
• 0
1
vote
3
replies
1.4k
views
Can CAMERA analyze just one particular pathway
pathway
ORA
limma
CAMERA
DGE
updated 2.2 years ago by
Gordon Smyth
53k • written 2.2 years ago by
manuelsokolov
• 0
5
votes
5
replies
1.5k
views
limma output for epic array methylation data
linearregression
epicarray
MethylationArray
limma
2.2 years ago
Jitendra
▴ 10
2
votes
5
replies
2.8k
views
removing the batch effect for vst counts and defining the batches in removeBatchEffect function
DESeq2
BatchEffect
limma
updated 2.2 years ago by
Gordon Smyth
53k • written 2.2 years ago by
Sara
• 0
2
votes
3
replies
3.0k
views
bulk RNA-seq analysis using R : batch effect : One question concerning Combat-seq and one question concerning DESeq2 design = batch + condition
BatchEffect
sva
DESeq2
RNASeqData
limma
updated 2.2 years ago by
James W. MacDonald
68k • written 2.2 years ago by
D-Bug
▴ 10
6
votes
7
replies
1.5k
views
Adding a group of samples reduces DEGs in other groups
RNASeq
limma
updated 2.3 years ago by
Gordon Smyth
53k • written 2.3 years ago by
Jonathan
▴ 10
1
vote
2
replies
1.6k
views
loading scores using plotMDS in limma
plotMDS
limma
2.3 years ago • updated 2.2 years ago
Cen
• 0
2
votes
1
reply
1.2k
views
Grouping DEGs yields varying results
RNASeq
limma
updated 2.3 years ago by
Gordon Smyth
53k • written 2.3 years ago by
Jonathan
▴ 10
0
votes
6
replies
1.4k
views
Questionable limma results for differential expression on RNA-seq
RNASeqData
DifferentialExpression
limma
updated 2.3 years ago by
Gordon Smyth
53k • written 2.3 years ago by
gld-bioinf
• 0
0
votes
2
replies
1.2k
views
Fluidigm Data Batch Correction
sva
limma
updated 2.3 years ago by
Gordon Smyth
53k • written 2.3 years ago by
Khushbu
• 0
0
votes
2
replies
1.2k
views
smallRNA-seq analysis batch correction in limma
BatchEffect
limma
2.3 years ago
Eleonora
• 0
3
votes
2
replies
772
views
For limma, if I leave coef=NULL, which test is the P value for?
limma
updated 2.3 years ago by
Gordon Smyth
53k • written 2.3 years ago by
S
• 0
4,225 results • Page
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Comment: Save the Date: BioC2026
by
eja.gsssssswwse.r.m
• 0
Que notícia incrivel sobre o BioC2026 Para quem gosta de aproveitar o conteudo online, também e possvel Baixar [snaptube versão antiga][1] …
Comment: Ensembl 115 has been released!
by
eja.gsssssswwse.r.m
• 0
Keeping up with Ensembls latest release ensures access to cutting-edge genomic information. For those balancing research and leisure, a mob…
Answer: After running samtools, the featureCounts command crashed.
by
Kevin Blighe
★ 4.0k
Hi Rui Tang, The "buffer overflow detected" error in featureCounts usually stems from a corrupted or malformed GTF file, often due to tr…
Answer: Problem with the TMB plot
by
Kevin Blighe
★ 4.0k
Hi, The linear TMB plot with no clustering suggests your variant calls may lack sample-specific discrimination, likely due to filtering ap…
Answer: gene Set with high AUC score but no cells assigned to cell type
by
Kevin Blighe
★ 4.0k
Hi, You have correctly identified the issue: AUCell's automatic threshold selection is conservative by design, aiming for specificity to…
Votes
Answer: DESeq2 design for haplotype MPRA
Answer: Failure to download resources (MeSHDb) from AnnotationHub
Answer: Failure to download resources (MeSHDb) from AnnotationHub
Answer: Suppress warning in RHDF5 write
Answer: Suppress warning in RHDF5 write
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