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600
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Help with the code for "BiocNeighbors::generic_find_knn() function used by scran::quickCluster()
BiocNeighbors
generic_find_knn
scran
quickCluster
2 days ago • updated 1 day ago
Arctic
• 0
0
votes
1
reply
460
views
DESeq2
org.Mmu.eg.db
DESeq2
TimeCourse
DMSOvsdrug
RNASeqData
updated 2 days ago by
ATpoint
★ 4.8k • written 3 days ago by
Cosmic
• 0
0
votes
1
reply
472
views
Mismatch between Illumina Mouse Methylation BeadChip annotation and genome browsers (UCSC/Ensembl)
methylationArrayAnalysis
MethylationArrayData
updated 3 days ago by
James W. MacDonald
68k • written 3 days ago by
luisa.turco
• 0
1
vote
4
replies
1.3k
views
Package developing and interoperation with Bioconductor
Package
Bioconductor
4 days ago • updated 3 days ago
slizchap
• 0
4
votes
6
replies
1.1k
views
Surprising behavior for DEXseq dispersion estimate plot?
DESeq2
DEXSeq
updated 3 days ago by
ATpoint
★ 4.8k • written 26 days ago by
Elijah
• 0
0
votes
2
replies
545
views
Error in H5Dclose(h5dataset) when trying to read in kallisto h5 files
tximport
rhdf5
updated 3 days ago by
Mike Smith
★ 6.6k • written 4 days ago by
Sofia
• 0
1
vote
1
reply
704
views
ComBat with repeated measures
ComBat
sva
updated 3 days ago by
ATpoint
★ 4.8k • written 4 days ago by
s20
• 0
0
votes
0
replies
29
views
News:
List of Deprecated Packages for Bioc3.21
devel
Release
release
Devel
4 days ago
shepherl
4.1k
0
votes
0
replies
28
views
News:
Bioconductor 3.21 Release Schedule Important Deadlines Approaching
Software
Release
release
4 days ago
shepherl
4.1k
0
votes
0
replies
42
views
Correlation threshold
MethylationArray
methylationArrayAnalysis
StatisticalMethod
5 days ago
user_bioinfo
• 0
0
votes
0
replies
4
views
Spam:
Does Spirit give free refunds?
ncdfFlow
hcg110.db
MethylSeekR
5 days ago
Haggu
10
0
votes
0
replies
28
views
Spam:
Can I change my BA flight to another date?
org.Sc.sgd.db
MafDb.1Kgenomes.phase1.GRCh38
ncdfFlow
5 days ago
Haggu
10
1
vote
0
replies
22
views
Spam:
What is the cheapest day to fly on American Airlines? {Ask_Expert}
cadd.v1.6.hg38
MafDb.1Kgenomes.phase1.GRCh38
ncdfFlow
5 days ago
Haggu
10
0
votes
0
replies
41
views
Spam:
Can I cancel my British Airways flight and get a refund?
CAGEr
gep2pep
hcg110.db
5 days ago
Haggu
10
0
votes
0
replies
8
views
Spam:
vjkftykdtyk
proDA
hcg110.db
zlibbioc
5 days ago
Haggu
10
0
votes
2
replies
619
views
Improving performance of edgeR and limma while adjusting for multiple confounders
edgeR
limma
updated 5 days ago by
ATpoint
★ 4.8k • written 6 days ago by
robinpaul85
• 0
0
votes
2
replies
376
views
Merging EPICV1 and V2 betas
minfiDataEPIC
minfi
updated 3 days ago by
Garbayo
• 0 • written 6 days ago by
rania.alanany
• 0
0
votes
0
replies
34
views
compute_fasta_digest does not match Salmon index hash
tximeta
6 days ago
Alex
• 0
0
votes
1
reply
156
views
Error in cnetplot
enrichplot
clusterProfiler
updated 6 days ago by
Guido Hooiveld
★ 4.1k • written 12 days ago by
Ayesha
• 0
0
votes
3
replies
471
views
getBM from biomaRt inconsistencies found with .gtf files across multiple species
.gtf
biomaRt
Ensembl
updated 5 days ago by
Mike Smith
★ 6.6k • written 6 days ago by
Benjamin
▴ 20
2
votes
3
replies
629
views
Explanation for ROAST results
CAMERA
limma
updated 5 days ago by
Gordon Smyth
52k • written 6 days ago by
Jay
• 0
0
votes
0
replies
88
views
How do I set up my DESeq analysis when I know a few vehicle control samples provide background effects we don't want to see in any of the subsequent …
DESeq2
RUVSeq
6 days ago
Simran
• 0
1
vote
1
reply
128
views
Merging annotation with differential expression output
annotation
RNASeqData
updated 6 days ago by
James W. MacDonald
68k • written 6 days ago by
AL
• 0
0
votes
2
replies
336
views
Annotation package for Manduca sexta
annotation
Manducasexta
AnnotationData
7 days ago • updated 5 days ago
GA
▴ 10
0
votes
5
replies
249
views
Bioconductor unable to update 'curl'
curl
HELP
7 days ago
kagodwi2
• 0
0
votes
4
replies
323
views
Ensembl site unresponsive via biomaRt
biomaRt
updated 6 days ago by
mdeea123
▴ 10 • written 7 days ago by
hebda
• 0
0
votes
1
reply
133
views
best way to grouping GSM belonging to different datasets (with different platforms) and compare differential gene expression
GEOquery
updated 7 days ago by
James W. MacDonald
68k • written 10 days ago by
Alexander
• 0
1
vote
2
replies
1.1k
views
CpGs with genomic positions greater than the chromosome size in EPICv2?
EPICv2
EPICv2manifest
11 days ago • updated 4 days ago
Joshua Llano
• 0
1
vote
4
replies
362
views
DESEQ2 looking at main effects while controlling for a continuous variable
DESeq2
11 days ago • updated 6 days ago
Lennie
• 0
4
votes
5
replies
1.3k
views
Using TPM from tximport of Salmon output for singscore
singscore
13 days ago • updated 10 days ago
Kent
• 0
5
votes
3
replies
759
views
Using edgeR::voomLmFit for the analysis of paired clinical RNA-seq samples with multiple cell types
edgeR
limma
voomLmFit
updated 12 days ago by
Gordon Smyth
52k • written 13 days ago by
Devin
▴ 10
2
votes
10
replies
3.9k
views
Problem at champ.load
ChAMPdata
ChAMP
updated 13 days ago by
Josh
• 0 • written 23 months ago by
angel
• 0
0
votes
1
reply
180
views
GAGE kegg.gsets() self-signed certificate error
gageData
gage
13 days ago • updated 11 days ago
Lucas
• 0
0
votes
2
replies
241
views
myvariant error
myvariant
getVariants
updated 13 days ago by
Christelle
• 0 • written 28 days ago by
Christelle
• 0
0
votes
4
replies
445
views
Guidance Needed: Best Practices for Handling Technical Replicates in RNA-seq Analysis
DESeq2
TechnicalReplicates
RNASeq
written 13 days ago by
questionanswer
• 0
0
votes
0
replies
34
views
DiffBind multi-tissue comparison
DiffBind
14 days ago
lryrainche
• 0
1
vote
2
replies
388
views
affy::rma results doesn't match with ncbi website
affy
Preprocessing
Microarray
updated 14 days ago by
James W. MacDonald
68k • written 15 days ago by
akp9132
• 0
0
votes
4
replies
254
views
Problem installing package TxDb.Mmusculus.UCSC.mm10.knownGene
TxDb.Mmusculus.UCSC.mm10.knownGene
14 days ago • updated 13 days ago
Wolfgang RAFFELSBERGER
▴ 140
0
votes
0
replies
95
views
fgsea: ranking genes using log2FC and pvalues derived from spline model
fgsea
GeneSetEnrichment
splines
RNASeq
15 days ago
GT
• 0
1
vote
1
reply
769
views
Use of org.Rn.eg.db with GRCr8 reference genome
DESeq2
org.Rn.eg.db
updated 17 days ago by
James W. MacDonald
68k • written 17 days ago by
Erika
• 0
0
votes
2
replies
605
views
Clarification on GOALL / GO2ALLORFs mapping
org.Sc.sgd.db
18 days ago • updated 12 days ago
DavideSant
• 0
2
votes
2
replies
1.1k
views
Limma - Complex 2-way multi-level contrast with paired samples
edgeR
contrastmatrix
limma
20 days ago • updated 14 days ago
Elizabeth
• 0
1
vote
2
replies
1.2k
views
[ChIP-seq] DESeq2 on counts matrix from union set of called peaks
csaw
ChIPseq
DESeq2
DiffBind
20 days ago • updated 19 days ago
Luca
• 0
0
votes
1
reply
277
views
Discrepancy between Excel TPP-TR reported values and the Melt Curve reported values
TPP
updated 19 days ago by
James W. MacDonald
68k • written 20 days ago by
flowreen.shikwana
• 0
1
vote
3
replies
819
views
Loading Ensembl 98 EnsDb from Annotation Hub fails with database disk image malformed error
signac
AnnotationHub
written 21 days ago by
AB
▴ 110
0
votes
1
reply
174
views
Transcript ID Mismatch in riboWaltz Annotation Table
RiboProfiling
RiboSeq
updated 20 days ago by
shepherl
4.1k • written 20 days ago by
ramya2kumar0
• 0
0
votes
4
replies
513
views
Using tximport for kallisto aligned TOIL data
kallisto
tximport
TOIL
25 days ago • updated 14 days ago
Nicholas
• 0
0
votes
1
reply
286
views
Reading gene expression data in GPR format and converting it to xlsx format
BiocWorkflowTools
BiomedicalInformatics
GeneExpression
updated 21 days ago by
James W. MacDonald
68k • written 21 days ago by
Kiana
• 0
0
votes
0
replies
57
views
Simple confidence intervall Gviz
Gviz
21 days ago
William
• 0
1
vote
3
replies
19k
views
Warning message---BiocManager::install
BiocManager::install
written 3.6 years ago by
Mengfei
• 0
46,427 results • Page
1 of 929
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Replies
Comment: single-cells RNA-seq analysis by MAST with unbalanced group size
by
achoppe
▴ 10
Hello! I also have compared uneven groups of cells - 517 cells in one group and 26 in the other. I am wondering if you know any published …
Comment: DESeq2 model - How to test case/control time course model when taking account wi
by
wuwenhui2
• 0
Thanks, I figured it out.
Comment: Design Matrix with paired and independent samples plus RUVg Spike-in normalizati
by
Mei
• 0
I have a similar experiment with 7 paired samples (T0 and T1) in each of 4 outcome groups. I am using RUVr combined with limma-voom, so I a…
Comment: Help with the code for "BiocNeighbors::generic_find_knn() function used by scran
by
Arctic
• 0
Many thanks for the link to the C++ code. I will see if I can find someone with C++ experience to help me with the code breakdown from her…
Answer: Help with the code for "BiocNeighbors::generic_find_knn() function used by scran
by
Aaron Lun
★ 28k
It's calling C++ code, see the relevant function definitions on [GitHub](https://github.com/knncolle/BiocNeighbors/blob/master/src/generics…
Votes
A: single-cells RNA-seq analysis by MAST with unbalanced group size
Comment: plyranges: find exact GRanges match keeping metadata columns
Answer: Help with the code for "BiocNeighbors::generic_find_knn() function used by scran
Is it possible to speed up VariantAnnotation's rowRanges function when converting to a dataframe?
Answer: Is it possible to speed up VariantAnnotation's rowRanges function when convertin
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