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Showing :
questions
0
votes
0
replies
1.1k
views
Correct creation of design matrix in limma for testing a specific comparison of interest in a microarray dataset
limma
microarray
design and contrast matrix
8.1 years ago
svlachavas
▴ 830
8
votes
12
replies
4.2k
views
Interaction models in limma and multiple factor assessement regarding microarray statistical inference
limma
microarray
interaction model
multiple factor design
makeContrasts
updated 8.2 years ago by
Aaron Lun
★ 28k • written 8.2 years ago by
svlachavas
▴ 830
2
votes
4
replies
1.9k
views
Weird error after trying to subset an microarray expression set with gene symbols from topTable function from limma
expressionset
limma
annotation
affymetrix microarrays
updated 8.3 years ago by
Martin Morgan
25k • written 8.3 years ago by
svlachavas
▴ 830
1
vote
2
replies
1.9k
views
Evaluation of diagnostic plot resulted from ComBat function regarding batch effect correction of a merged microarray dataset
ComBat
diagnostic plot
batch effect
affymetrix microarrays
sva
updated 8.3 years ago by
W. Evan Johnson
▴ 850 • written 8.3 years ago by
svlachavas
▴ 830
2
votes
2
replies
2.1k
views
Error while calling function topTable() from limma R package in microarray data analysis
limma
microarray
a4Core
topTable
statistical inference
updated 8.3 years ago by
Aaron Lun
★ 28k • written 8.3 years ago by
svlachavas
▴ 830
0
votes
0
replies
1.9k
views
Appropriate implementation of ComBat function for known batch effect correction and alternative methodologies of merging microarray datasets
sva
ComBat
customcdf
affymetrix microarrays
limma
8.3 years ago
svlachavas
▴ 830
0
votes
1
reply
1.3k
views
Appropriate selection of DE list in limma before and after implementation of arrayWeights in conjuction with duplicateCorrelation functions
limma
microarray
multifactorial design
duplicatecorrelation
arrayweights
8.4 years ago
svlachavas
▴ 830
7
votes
6
replies
3.2k
views
Interpretation of mroast gene set analysis in R and appropriate use of the function barcode plot regarding a microarray dataset
limma
mroast
barcodeplot
KEGG
gene set testing
updated 8.5 years ago by
Gordon Smyth
50k • written 8.5 years ago by
svlachavas
▴ 830
0
votes
0
replies
1.1k
views
Background correction arguments in R package GCRMA for microarray pre-processing analysis
gcrma
normalization
background correction
microarray
8.5 years ago
svlachavas
▴ 830
2
votes
10
replies
6.1k
views
Install older specific version from an R package that is on the Bioconductor Repository
Bioconductor
biocLite
R packages
oldversion
8.5 years ago
svlachavas
▴ 830
3
votes
5
replies
2.3k
views
Explanation of warning output of pathview regarding visualization of a KEGG pathway with Graphviz format
pathview
clusterProfiler
KEGGpath
visualization
Graphviz
updated 8.5 years ago by
Luo Weijun
★ 1.6k • written 8.5 years ago by
svlachavas
▴ 830
3
votes
8
replies
26k
views
"Error in readRDS(file) : unknown input format" appearing every time starting Rstudio after BiocUpgrade
BiocUpgrade
Rstudio
Bioconductor
R3.2.2
8.5 years ago
svlachavas
▴ 830
4
votes
4
replies
2.5k
views
Background correction in Illumina beadchip microarrays with limma neqc function
illumina human ht-12 v4
limma
background correction
BeadStudio
microarray
updated 8.5 years ago by
Gordon Smyth
50k • written 8.5 years ago by
svlachavas
▴ 830
7
votes
2
replies
2.2k
views
Appropriate explanation of the methodology behind arrayWeights function from limma R package
limma
arrayWeights
variance
sampleQuality
microarray
updated 8.6 years ago by
Ryan C. Thompson
★ 7.9k • written 8.6 years ago by
svlachavas
▴ 830
4
votes
8
replies
1.7k
views
Combination of duplicateCorrelation with arrayWeights to increase power for DE detection in multilevel experiments
limma
duplicatecorrelation
arrayweights
microarray
updated 8.6 years ago by
Gordon Smyth
50k • written 8.6 years ago by
svlachavas
▴ 830
1
vote
2
replies
1.6k
views
Possible methodologies of machine learning in R that can assimilate continuous variables along gene expression data for microarray classification
classification
machinelearning
microarray
multivariate
caret
updated 8.6 years ago by
Steve Lianoglou
★ 13k • written 8.6 years ago by
svlachavas
▴ 830
0
votes
0
replies
1.5k
views
Possible methodologies for missing value imputation of continuous variables in a data frame in R
missing data
missing value imputation
impute
MICE
bioconductor
8.6 years ago
svlachavas
▴ 830
0
votes
0
replies
1.3k
views
Possible methodologies for constructing multi-level comparisons in limma
limma paired analysis
multiple factor design
affymetrix microarrays
duplicatecorrelation
8.6 years ago
svlachavas
▴ 830
18
votes
18
replies
4.8k
views
Using of limma moderated t-test with "corrected" expression matrix resulting from ComBat batch effect correction
limma
batch effect
ComBat
differential gene expression
updated 8.6 years ago by
W. Evan Johnson
▴ 850 • written 8.6 years ago by
svlachavas
▴ 830
0
votes
1
reply
1.8k
views
Questions regarding removal and following re-installation of a specific R package using a custom library path
package installation
custom library path
biocLite
bioconductor
8.7 years ago
svlachavas
▴ 830
0
votes
0
replies
1.3k
views
Error with R package RontoTools regarding administrator issues downloading updated KEGG data
ROntoTools
Rstudio
bioconductor
administratorIssues
pathway analysis
8.7 years ago
svlachavas
▴ 830
3
votes
4
replies
1.4k
views
Problem regarding the explanation of log-fold changes of individual coefficients in limma after eBayes
limma
logfoldchange
limma design matrix
paired samples
affymetrix microarrays
updated 8.7 years ago by
Ryan C. Thompson
★ 7.9k • written 8.7 years ago by
svlachavas
▴ 830
11
votes
16
replies
1.8k
views
Possible explanations and suggestions corresponding the interprentation of results of limma multifactorial design
limma
multifactorial design
diagnostic plots
affymetrix microarrays
updated 8.7 years ago by
James W. MacDonald
66k • written 8.7 years ago by
svlachavas
▴ 830
0
votes
0
replies
1.2k
views
Possible(validated) methodology implemented in R for integrating and analyzing clinical data with gene expression data in R
data integration
clinicaldata
gene expression data
PET
8.7 years ago
svlachavas
▴ 830
2
votes
5
replies
5.5k
views
Update R in Rstudio to specific version 3.2.1 in windows
updateR
rstudio
Rversion3.2.1
updated 8.7 years ago by
Dan Tenenbaum
★ 8.2k • written 8.7 years ago by
svlachavas
▴ 830
0
votes
0
replies
2.6k
views
Problem with the colors in the heatmap.2 function and the color key values range
gplots
heatmap.2
affymetrix microarrays
color key
8.7 years ago
svlachavas
▴ 830
12
votes
20
replies
2.1k
views
Possible implementation of multifactorial contrasts in limma regarding a microarray dataset
limma
multifactorial design
design and contrast matrix
affymetrix microarrays
updated 8.7 years ago by
Aaron Lun
★ 28k • written 8.7 years ago by
svlachavas
▴ 830
2
votes
2
replies
2.6k
views
Correct creation of design matrix in limma regarding a multi-level experiment
limma
multiple factor design
affymetrix microarrays
limma paired analysis
updated 8.7 years ago by
Gordon Smyth
50k • written 8.7 years ago by
svlachavas
▴ 830
4
votes
8
replies
1.9k
views
Annotation Problem regarding double platform merged microarray eset using the inSilicoMerging R package, after differential expression analysis
inSilicoMerging
doubleannotation
affymetrix microarrays
limma
inSilicoDB
8.7 years ago
svlachavas
▴ 830
2
votes
4
replies
4.4k
views
Error and questions about clustering & ploting functions in r packages cluster and mclust regarding kmeans method
cluster
mclust
limma
clusplot
kmeans
8.8 years ago
svlachavas
▴ 830
18
votes
37
replies
17k
views
Correct construction of design matrix in limma for multiple contrasts for gene expression profiling
limma
illumina
differential gene expression
multiple comparisons
design matrix
9.0 years ago • updated 8.8 years ago
svlachavas
▴ 830
1
vote
2
replies
2.4k
views
(Gene-set)Pathway analysis based on network/pathway topology in R
SPIA
functional enrichment
pathway topology
pathway analysis
bioconductor
8.8 years ago
svlachavas
▴ 830
1
vote
2
replies
10k
views
Use of various distance measures and clustering methods in heatmap creation
gplots
heatmap.2
bioconductor
pearsoncorrelation
average
8.9 years ago
svlachavas
▴ 830
6
votes
4
replies
4.1k
views
Merge different datasets and perform differential expression analysis in limma
insilicomerging
batcheffect
limma
differential gene expression
bioconductor
updated 8.9 years ago by
Aaron Lun
★ 28k • written 8.9 years ago by
svlachavas
▴ 830
0
votes
2
replies
1.4k
views
Possible construction of heatmap for clustering only genes for different treatments and not samples
heatmap.2
clustering
common DEG genes
bioconductor
updated 8.9 years ago by
James W. MacDonald
66k • written 8.9 years ago by
svlachavas
▴ 830
7
votes
10
replies
1.7k
views
Possible TF binding site enrichment analysis through mroast and conversion problems
TF binding site analysis
bioconductor
mroast
limma
promoter analysis
updated 8.9 years ago by
Aaron Lun
★ 28k • written 8.9 years ago by
svlachavas
▴ 830
5
votes
11
replies
1.8k
views
Appropriate methodologies for using various inputs(GOs, gene-sets) for mroast testing
limma
mroast
GSEA
GO
illumina human ht-12 v4
updated 8.9 years ago by
Aaron Lun
★ 28k • written 8.9 years ago by
svlachavas
▴ 830
2
votes
2
replies
1.6k
views
Annotation problems regarding quality information for Illumina HumanHT-12 v4-illuminaHumanv4.db
illumina human ht-12 v4
illuminahumanv4.db
filtering on probe annotation
illumina
updated 9.0 years ago by
Mike Smith
★ 6.5k • written 9.0 years ago by
svlachavas
▴ 830
1
vote
2
replies
1.4k
views
Annotation issues with illumina microarray preprocessing with limma
limma
illumina human ht-12 v4
annotationdbi
lumihumanAll.db
lumihumanidmapping
updated 9.0 years ago by
Gordon Smyth
50k • written 9.0 years ago by
svlachavas
▴ 830
2
votes
8
replies
3.6k
views
Problems importing Illumina raw data with lumi R package
Illumina Human HT-12 v4
lumi
limma
microarray
updated 9.0 years ago by
Gordon Smyth
50k • written 9.0 years ago by
svlachavas
▴ 830
22
votes
4
replies
10.0k
views
Correct assumptions of using limma moderated t-test
limma
statistical inference
variance test
bioconductor
updated 9.0 years ago by
Gordon Smyth
50k • written 9.0 years ago by
svlachavas
▴ 830
6
votes
10
replies
1.8k
views
Possible implementation of roast/mroast for testing common DE patterns across two different experiments
gene set testing
roast
mroast
differential gene expression
bioconductor
9.0 years ago
svlachavas
▴ 830
2
votes
3
replies
2.8k
views
Questions in limma about multifactorial design and possible batch effect correction
limma
batcheffect
batcheffectcorrection
multiple factor design
updated 9.0 years ago by
James W. MacDonald
66k • written 9.0 years ago by
svlachavas
▴ 830
0
votes
1
reply
2.4k
views
Error while trying to upgrade R to version 3.2
bioconductor
upgrade
installr
Windows8
R 3.2
9.1 years ago
svlachavas
▴ 830
0
votes
0
replies
1.4k
views
Error in R package "cancerclass" with function nvalidate
cancerclass
bioconductor
machinelearning
classification
9.1 years ago
svlachavas
▴ 830
0
votes
0
replies
1.6k
views
Machine learning methods for feature selection and possible correlation with clinical data
machinelearning
clinicaldata
biomarkers
data integration
bioconductor
9.1 years ago
svlachavas
▴ 830
2
votes
16
replies
2.7k
views
Possible ways of performing non-specific intensity filtering on Perfect-match only affymetrix array
oligo
DABG
non-specific filtering
primeview
9.1 years ago
svlachavas
▴ 830
0
votes
0
replies
1.2k
views
Possible implementation of two class paired Rank Products in r with package RankProd
RankProd
pairedtest
bioconductor
biologicalreplicates
9.1 years ago
svlachavas
▴ 830
1
vote
5
replies
1.9k
views
Appropriate merge of batches of the same array to create a final total ExpressionSet
frma
bioconductor
batcheffect
Primeview
insilicomerging
updated 9.1 years ago by
Matthew McCall
▴ 830 • written 9.1 years ago by
svlachavas
▴ 830
0
votes
0
replies
1.2k
views
Correst use of GeneOverlap R Package
GeneOverlap
DEGgenes
affymetrixchip
bioconductor
9.1 years ago
svlachavas
▴ 830
121 results • Page
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