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14
votes
17
replies
1.2k
views
Why p value inconsistent when using different number of pathway score?
limma
17 days ago • updated 6 days ago
Chris
• 0
8
votes
7
replies
1.7k
views
SGSeq: moving toward diffex from SGSeq analysis
sgseq
rnaseq
updated 2 days ago by
Sara
• 0 • written 6.7 years ago by
Sylvain Foisy
▴ 80
5
votes
6
replies
2.8k
views
Although I successfully installed the package "simpleaffy'' , I cannot library it. Why?
simpleaffy
updated 5 days ago by
James W. MacDonald
65k • written 2.3 years ago by
yanchangjian2019
• 0
4
votes
2
replies
547
views
Why does GSEA on edgeR results for randomized samples give highly significant p-values?
fgsea
edgeR
5 days ago • updated 1 day ago
gene_bioconductor
▴ 10
4
votes
9
replies
436
views
Memory errors using read.bismark?
dmrseq
bsseq
26 days ago • updated 19 hours ago
Juan Higareda
• 0
3
votes
0
replies
87
views
News:
Bioconductor 3.19 is Released!
Release
Bioconductor
Packages
Software
6 days ago
shepherl
3.9k
3
votes
1
reply
82
views
How to save the DEXSeq results
DEXSeq
updated 1 day ago by
Michael Love
42k • written 1 day ago by
Sara
• 0
3
votes
4
replies
196
views
Method to find pathways different between 2 groups
fgsea
GSVA
CAMERA
updated 11 hours ago by
Gordon Smyth
50k • written 2 days ago by
Chris
• 0
3
votes
1
reply
1.5k
views
Limma without eBayes, is it indistunguishable from Ordinary Least Square?
Limma
ebayes
bayesian
ls
updated 7 hours ago by
Gordon Smyth
50k • written 5.6 years ago by
CantExitVIM
▴ 10
3
votes
5
replies
178
views
Help with running egsea()
EGSEA
1 day ago • updated 7 hours ago
Chris
• 0
2
votes
3
replies
185
views
Too many significant genes when integrating gtex and tcga
RNA-seq
DESeq2
updated 3 days ago by
ATpoint
★ 4.1k • written 4 days ago by
Reza
• 0
2
votes
3
replies
172
views
package goseq seems to be not available on the latest version of R
goseq
updated 1 day ago by
Gordon Smyth
50k • written 4 days ago by
Patrycja
▴ 20
2
votes
2
replies
146
views
fgsea significant result
fgsea
3 days ago • updated 2 days ago
Chris
• 0
1
vote
2
replies
193
views
Improving the design matrices vignette in RNAseq123
RNAseq123
16 days ago • updated 1 day ago
Lluís Revilla Sancho
▴ 730
1
vote
1
reply
71
views
minfi latest update for EPIC V2 chip
minfi
minfiDataEPIC
updated 21 hours ago by
James W. MacDonald
65k • written 1 day ago by
e1271094
• 0
1
vote
1
reply
74
views
error in limma , contrast.matrix Number of rows of contrast matrix must match number of coefficients in fit
limma
updated 17 hours ago by
James W. MacDonald
65k • written 18 hours ago by
zzrammal
• 0
1
vote
6
replies
94
views
Extremely small p-values using Limma for proteomic data
Proteomics
limma
updated 1 hour ago by
Robert Castelo
★ 3.3k • written 19 hours ago by
Abbey
• 0
1
vote
4
replies
483
views
DEseq2 coefficient
DESeq2
coefficient
10 weeks ago • updated 6 days ago
JKim
• 0
1
vote
5
replies
1.4k
views
Cannot connect to ExperimentHub server
ExperimentHub
updated 6 hours ago by
Jiayu
• 0 • written 5 months ago by
yanling
• 0
1
vote
3
replies
218
views
Getting Error in hclust(d, method = method): NA/NaN/Inf in foreign function call when trying to subset pheatmap
DESeq2
updated 2 hours ago by
ATpoint
★ 4.1k • written 6 days ago by
angelathuynh5
• 0
1
vote
1
reply
110
views
Handling multiple differential expression comparisons
DESeq2
updated 2 days ago by
Michael Love
42k • written 4 days ago by
Zainab
▴ 10
1
vote
0
replies
207
views
News:
Nominations for Bioconductor Awards 2024!
Recognition
Awards
Bioconductor
Bioc204
6 weeks ago • updated 1 day ago
shepherl
3.9k
1
vote
1
reply
81
views
Trim/Filter out-of-bounds GRanges
GenomicRanges
updated 1 day ago by
Michael Love
42k • written 1 day ago by
mat149
▴ 70
1
vote
2
replies
239
views
Get genomic coordinates of CpGs sites (chromosomes, genomic position)
GenomeWideAssociation
SequenceAnnotation
MethylationArray
GenomicDistributionsData
7 days ago • updated 6 days ago
Yveto
• 0
1
vote
2
replies
312
views
CombineArrays for EPIC and EPIC V2
EPICV1
Methylation
combineArrays
minifi
EPICv2manifest
4 weeks ago • updated 4 days ago
Kim
• 0
1
vote
2
replies
340
views
limma Intercept vs No-intercept models completely changing DMR results?
limma
DMRcate
MethylationArray
EPICV2
updated 4 days ago by
Gordon Smyth
50k • written 4 days ago by
Kim
• 0
1
vote
3
replies
234
views
Mac ARM64 build report for BioC 3.19 from 'kjohnson3' reporting ERROR which it does not happen in Linux
GenomAutomorphism
updated 1 day ago by
Hervé Pagès
16k • written 2 days ago by
robersy
• 0
0
votes
3
replies
149
views
More regions in union when increasing DBA$config$mergeOverlap
DiffBind
7 days ago • updated 52 minutes ago
Ian D.
▴ 70
0
votes
3
replies
163
views
Store output of matchPWM()
biostrings
Biostrings
updated 6 days ago by
James W. MacDonald
65k • written 6 days ago by
mat149
▴ 70
0
votes
3
replies
259
views
log2FoldChange value is way too different when compared with counts(dds)
DESeq2
updated 6 days ago by
Michael Love
42k • written 7 days ago by
HAK
• 0
0
votes
2
replies
172
views
limma-voom: Calculate the log-fold change in gene expression within a sample
limma
RNASeq
voom
written 15 days ago by
taur.vil
• 0
0
votes
3
replies
152
views
Differences in differential analysis methods for RNA-Seq
DESeq2
StatisticalMethod
Proteomics
DifferentialExpression
RNASeq
updated 6 days ago by
ATpoint
★ 4.1k • written 6 days ago by
james.zhang20
• 0
0
votes
1
reply
78
views
Job:
Postdoctoral Position in Bioinformatics - Mainz, Germany
JobPosting
written 6 days ago by
4r-rtg
• 0
0
votes
0
replies
47
views
How to create consensus peak sets for each group to use in DiffBind?
DiffBind
5 days ago
Ian D.
▴ 70
0
votes
0
replies
51
views
DiffBind: no peaks in DBA object
DiffBind
macs2
chipseq
5 days ago
yvonneh
• 0
0
votes
2
replies
114
views
DESeq2 v1.35.0
DESeq2
updated 5 days ago by
Michael Love
42k • written 5 days ago by
Espresso
• 0
0
votes
0
replies
56
views
flowStats for CyTOF
flowStats
5 days ago
tholmes
• 0
0
votes
1
reply
109
views
Gene-by-sample covariates in limma
Metabolomics
limma
updated 5 days ago by
Gordon Smyth
50k • written 5 days ago by
c53aba27
• 0
0
votes
1
reply
128
views
NEED FOR NESSASORY HELP
RNASeqData
edgeR
updated 5 days ago by
Gordon Smyth
50k • written 5 days ago by
z_bahari
• 0
0
votes
2
replies
150
views
Deseq2 and Normalization of RNA sequencing data
DESeq2
6 days ago • updated 5 days ago
kcarey
• 0
0
votes
0
replies
129
views
One error problem occurred caused by data type during using GDCprepare function of TCGAbiolinks to handle TCGAbiolinks BRCA data
GDCRNATools
TCGA
13 days ago • updated 5 days ago
glaciya2018
• 0
0
votes
2
replies
129
views
Timecourse RNASeq analysis
DESeq2
ImpulseDE2
timecour
timecoursedata
moanin
8 days ago • updated 5 days ago
Aurora
• 0
0
votes
0
replies
72
views
dba.plotProfile() plotting and interpretation
DiffBind
4 days ago
Henry
▴ 10
0
votes
0
replies
95
views
Empty table plot using plotGseaTable()
fgsea
6 days ago • updated 4 days ago
Chris
• 0
0
votes
6
replies
224
views
Once again a "Model matrix not full rank"
DESeq2
design
coldata
updated 4 days ago by
swbarnes2
★ 1.3k • written 5 days ago by
arfranco
▴ 130
0
votes
5
replies
2.8k
views
DNAString: Standard checksum function?
Biostrings
FASTA
sequencing
8.2 years ago • updated 2 days ago
Henrik Bengtsson
★ 2.4k
0
votes
3
replies
116
views
Couldn't connect to server while using "pathways"
graphite
updated 1 day ago by
Michael Love
42k • written 2 days ago by
fduguchunhui
• 0
0
votes
3
replies
3.7k
views
[Mfuzz] Error in cmeans(exprs(eset)
Mfuzz
Mfuzz
updated 1 day ago by
Caio
• 0 • written 13.1 years ago by
boczniak767
▴ 720
0
votes
34
replies
2.6k
views
How to use bootRanges to bootstrap small RNA loci (nullranges package)
bootRanges
nullranges
15 months ago • updated 1 day ago
Poonam
• 0
0
votes
0
replies
28
views
need help with Diffbind multiple groups
DiffBind
ChIPSeqData
1 day ago
Dinesh
• 0
53 results • Page
1 of 2
Recent ...
Replies
Comment: More regions in union when increasing DBA$config$mergeOverlap
by
Ian D.
▴ 70
Nudging my question. I could do with confirmation before proceeding with my current projects. Thank you.
Comment: Extremely small p-values using Limma for proteomic data
by
Robert Castelo
★ 3.3k
From the point of view of visualization, I find handy the fact that raw p-values give more resolution than adjusted ones, which allows one …
Comment: deseq2 results
by
ATpoint
★ 4.1k
> the results are not satisfactory to me Well, what is your question? The DESeq2 vignette covers how to do analysis, and some diagnostics…
Comment: Extremely small p-values using Limma for proteomic data
by
ATpoint
★ 4.1k
It's not an implementation problem I am discussing (it's trivial obviously) -- more that for most purposes the y-axis metric should be the …
Comment: Extremely small p-values using Limma for proteomic data
by
Robert Castelo
★ 3.3k
For visualization purposes you can draw an horizontal line at the p-value cutoff that meets the experiment-wide FDR cutoff. For instance, i…
Votes
Answer: minfi latest update for EPIC V2 chip
A: Error in DESeqDataSet : some values in assay are not integers
Answer: Cannot connect to ExperimentHub server
Answer: confused with tximport counts abundance using salmon input
Answer: Getting Error in hclust(d, method = method): NA/NaN/Inf in foreign function call
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