1
vote
2
replies
104
views
Limma-voom sample weights and impact on DEG numbers
limma
written 3 days ago by ▴ 20
0
votes
1
reply
83
views
wgcna module preseravtion taking too long?
WGCNA
updated 3 days ago by ★ 5.0k • written 10 days ago by • 0
0
votes
1
reply
176
views
Question about RE-agnostic mode for intact Hi-C and Micro-C normalization(HiCDCPlus)
HiC HiCDCPlus
written 17 days ago by • 0
0
votes
3
replies
144
views
DESeq2 - how many surrogate variables from svaseq, use of lfcshrink
sva lfcshrink DESeq2
written 6 days ago by • 0
0
votes
6
replies
2.5k
views
Ensembl site unresponsive via biomaRt
biomaRt
written 9 months ago by • 0
0
votes
3
replies
174
views
segfault in edgeR glmQLFit
edgeR
updated 3 days ago by 53k • written 6 days ago by • 0
0
votes
3
replies
271
views
How does contrasts.fit do in limma to extract comparisons with a model having interaction terms?
limma
updated 6 days ago by 53k • written 8 days ago by • 0
0
votes
0
replies
56
views
News: Opportunity to host EuroBioC2026 Preconference workshops!
Conference Workshop Bioconductor
9 days ago laurah ondari • 0
0
votes
0
replies
69
views
Clarification on counting in Rsubread (featureCounts)
featureCounts Rsubread
11 days ago • updated 3 days ago Luca • 0
0
votes
1
reply
119
views
NUPOP usage
TOAST
updated 15 days ago by 4.2k • written 15 days ago by • 0
1
vote
2
replies
278
views
News: Important: Bioconductor Release 3.22 Delayed
release
written 8 weeks ago by 4.2k
0
votes
2
replies
220
views
BiocParallel (and DESeq2) - wrong args for environment subassignment
BiocParallel DESeq2
updated 21 days ago by 43k • written 22 days ago by • 0
0
votes
1
reply
177
views
PTM analysis in LIMPA
limpa
updated 21 days ago by 53k • written 22 days ago by • 0
1
vote
0
replies
182
views
News: Upcoming Ensembl API and data access changes - new blog post available
ensembl mart biomaRt ensembldb
24 days ago Ensembl_Jorge ▴ 10
0
votes
2
replies
211
views
problem reading bam files into nucleR
nucleR
updated 24 days ago by 68k • written 28 days ago by ▴ 10
0
votes
0
replies
14
views
Spam: Career Growth After CCNP Certification Training: Roles, Salaries & Opportunities
ScreenR
24 days ago Maya 0
0
votes
0
replies
9
views
Spam: Career Growth After CCNP Certification Training: Roles, Salaries & Opportunities
TOAST
24 days ago Maya 0
0
votes
0
replies
9
views
Spam: Career Growth After CCNP Certification Training: Roles, Salaries & Opportunities
ScreenR
24 days ago Maya 0
0
votes
0
replies
8
views
Spam: Career Growth After CCNP Certification Training: Roles, Salaries & Opportunities
ScreenR
24 days ago Maya 0
0
votes
0
replies
9
views
Spam: Career Growth After CCNP Certification Training: Roles, Salaries & Opportunities
ScreenR
24 days ago Maya 0
3
votes
6
replies
908
views
Highly similar RNA-seq samples in PCA - pooling or technical duplication?
RNASeq DESeq2 DifferentialExpression RNASeqData
written 5 weeks ago by • 0
0
votes
1
reply
1.3k
views
two questions about limma
Microarray limma Microarray limma
updated 26 days ago by 53k • written 18.8 years ago by ▴ 240
0
votes
1
reply
165
views
Question about DESeq2 Design for Paired Treatment Study
DESeq2
updated 26 days ago by ★ 5.0k • written 27 days ago by • 0
0
votes
1
reply
157
views
News: EuroBioC2026 abstract submission is open!
Conference Bioconductor
updated 4 days ago by • 0 • written 29 days ago by • 0
0
votes
1
reply
139
views
PFAM formats changed - is it still possible to use this with ISA?
IsoformSwitchAnalyzeR
updated 6 days ago by • 0 • written 4 weeks ago by • 0
0
votes
2
replies
212
views
DECIPHER DesignProbes unable to design FISH-probes
decipher FISH DECIPHER FISH-probe probe-design
updated 2 days ago by • 0 • written 4 weeks ago by • 0
0
votes
2
replies
1.2k
views
p.adjust BH Question
written 14.3 years ago by ▴ 10
1
vote
4
replies
398
views
Large logFC but somewhat high FDR
limpa
4 weeks ago • updated 24 days ago JKim • 0
0
votes
1
reply
208
views
Job: Bioinformatician at the Lausanne University Hospital
GenomicRanges JobPosting
updated 2 days ago by • 0 • written 4 weeks ago by ▴ 20
3
votes
5
replies
488
views
upstream git branches of bioc-release
Bioconductor
written 4 weeks ago by ▴ 10
0
votes
2
replies
181
views
limpa - drivers for unusually high standard error?
limpa
updated 4 weeks ago by 53k • written 4 weeks ago by • 0
1
vote
4
replies
1.9k
views
How can I correctly use phyloseq with Docker?
phylo phyloseq Docker
updated 13 days ago by • 0 • written 7 months ago by • 0
0
votes
1
reply
419
views
Boolean Gate Combination for Any 2 Positive Events in flowWorkspace
flowWorkspace FlowCytometry
updated 4 weeks ago by ★ 4.0k • written 5 months ago by • 0
0
votes
2
replies
1.1k
views
Install old version of DESeq2
apeglm Install DESeq2 version
updated 4 weeks ago by ★ 4.0k • written 5 months ago by • 0
0
votes
1
reply
390
views
Guidance Requested on GCN Network Analysis and Module Enrichment in R
BioNERO Bioconductor Arabidopsis_thaliana_Data
updated 4 weeks ago by ★ 4.0k • written 5 months ago by • 0
0
votes
2
replies
377
views
ORFik: spliced 5utr regions
splicing 5utr ORFik
updated 4 weeks ago by ★ 4.0k • written 5 months ago by • 0
0
votes
2
replies
446
views
BiocManager::install() doesn't work
Install Biocond
updated 4 weeks ago by ★ 4.0k • written 5 months ago by • 0
0
votes
2
replies
345
views
Results with PON give more variants
mutect2 variants pon
written 5 months ago by ▴ 10
0
votes
1
reply
289
views
Empty boxes in treemap plot rrvgo package
rrvgo
updated 4 weeks ago by ★ 4.0k • written 5 months ago by • 0
0
votes
1
reply
284
views
CRISPRSeek Question: changing weight and gRNA.size causes error
CRISPRseek CRISPR
updated 4 weeks ago by ★ 4.0k • written 5 months ago by • 0
0
votes
2
replies
475
views
Feedback needed on new user-friendly BED file tool
bedbaser offtopic
updated 4 weeks ago by ★ 4.0k • written 5 months ago by • 0
0
votes
1
reply
274
views
sigDF object in sesame
sesame sesameData
updated 4 weeks ago by ★ 4.0k • written 4 months ago by • 0
0
votes
3
replies
388
views
Create consensusMatrix for codon bases
Biostrings
updated 4 weeks ago by ★ 4.0k • written 4 months ago by • 0
0
votes
2
replies
457
views
Memory error while running alignments
DECIPHER Alignment
updated 4 weeks ago by ★ 4.0k • written 4 months ago by • 0
1
vote
11
replies
1.8k
views
Using DESeq2 on single cell RNA Seq data of same cell type but different conditions that were pseudo bulked
DESeq2 scRNAseq
updated 4 weeks ago by ★ 4.0k • written 4 months ago by • 0
0
votes
1
reply
282
views
Finding duplicated entries in GRangesList
GenomicRanges
updated 5 weeks ago by ★ 4.0k • written 4 months ago by • 0
0
votes
2
replies
311
views
DESeq2 on non-RNASeq counts data
DESeq2
updated 5 days ago by • 0 • written 4 months ago by • 0
0
votes
2
replies
475
views
After running samtools, the featureCounts command crashed.
RNASeqData Bioconductor RNASeq
updated 25 days ago by • 0 • written 3 months ago by • 0
0
votes
1
reply
530
views
Problem with the TMB plot
Bioconductor
updated 5 weeks ago by ★ 4.0k • written 3 months ago by • 0
0
votes
1
reply
304
views
mzR-Rcpp compiler version issue
Rcpp Perseus mzR
updated 5 weeks ago by 1.6k • written 4 months ago by • 0
1,000 results • Page 1 of 20
Recent ...
Replies
Comment: nice 3D displays for PCA analysis by adam80haynes • 0
That's a fascinating application of 3D printing in a scientific context. Using this technology to create custom lab equipment, models of mo…
Comment: Bioinformatician at the Lausanne University Hospital by TikTsokaasocissalpc • 0
The Random Word Generator in Italian is a useful tool for generating ideas and exploring new approaches, much like the innovative research …
Comment: DECIPHER DesignProbes unable to design FISH-probes by TikTsokaasocissalpc • 0
If you want to share your research progress and microbiome discoveries with colleagues or friends, [snaptroid android][1] download free mak…
Answer: Limma-voom sample weights and impact on DEG numbers by Gordon Smyth 53k
I recommend that you always use voomLmFit() instead of the earlier voom() or voomWithQualityWeights() functions. Personally, I would use sa…
Answer: wgcna module preseravtion taking too long? by ATpoint ★ 5.0k
WGCNA is not a Bioconductor package, you won't get an answer here. Consider biostars.org or the r/bioinformatics reddit. Note that 10 sampl…
Votes
Limma-voom sample weights and impact on DEG numbers
C: DESeq2 Following RSEM
Upcoming Ensembl API and data access changes - new blog post available
Comment: Highly similar RNA-seq samples in PCA - pooling or technical duplication?
Answer: Large logFC but somewhat high FDR
Awards • All
Popular Question to Gordon Smyth 53k
Popular Question to Hervé Pagès 16k
Popular Question to Vincent J. Carey, Jr. 6.7k
Popular Question to Istvan Albert ▴ 50
Popular Question to Dario Strbenac ★ 1.6k
Locations • All
United States, 14 minutes ago
Barcelona, Spain, 2 hours ago
United States, 5 hours ago
Sweden, 6 hours ago
The city by the bay, 7 hours ago
Traffic: 677 users visited in the last hour
Content Search
Users
Tags
Badges
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6