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0
votes
0
replies
35
views
I want my overlapping peaks to stop merging by default doing read counting (using DiffBind in R-studio)
peakoverlap
mergingpeaks
ChIPseq
DiffBind
1 day ago
atlanta
• 0
0
votes
1
reply
459
views
Differential expression analysis using two TCGA datasets
DifferentialExpression
TCGAbiolinks
RNASeq
updated 1 day ago by
ATpoint
★ 4.8k • written 2 days ago by
Shaimaa Gamal
• 0
1
vote
0
replies
331
views
Modelling gene program dynamics across time with {lemur}
lemur
3 days ago • updated 1 day ago
BiotechPedro
▴ 10
0
votes
0
replies
39
views
Intepretation of results
AUCell
4 days ago
jasperwong_123
• 0
0
votes
1
reply
269
views
DiffBind can't find a DAR
dar
ATACSeq
DiffBind
updated 5 days ago by
ATpoint
★ 4.8k • written 5 days ago by
Mengjun
• 0
1
vote
3
replies
730
views
DESeq - help with pair wise comparisons
DESeq2
5 days ago
bd2000
▴ 30
0
votes
0
replies
25
views
Spam:
Looking for Josey Wales Jacket?
MethylSeekR
8 days ago
Shoqz
0
0
votes
0
replies
106
views
Differing results with DESeq2
DESeq2
8 days ago • updated 3 days ago
hampsdiv
• 0
0
votes
1
reply
126
views
Issue with Soft-Thresholding in WGCNA
WGCNA
updated 10 days ago by
dirty.cougar.risi
• 0 • written 10 days ago by
Μαρία
• 0
0
votes
0
replies
18
views
Spam:
Experience lasting confidence with Vidalista 40 mg
org.Sc.sgd.db
11 days ago
irenejoshi07
0
0
votes
4
replies
1.1k
views
Error in H5Dclose(h5dataset) when trying to read in kallisto h5 files
tximport
rhdf5
16 days ago • updated 11 days ago
Sofia
• 0
1
vote
1
reply
753
views
ComBat with repeated measures
ComBat
sva
updated 15 days ago by
ATpoint
★ 4.8k • written 16 days ago by
s20
• 0
0
votes
0
replies
68
views
Correlation threshold
MethylationArray
methylationArrayAnalysis
StatisticalMethod
17 days ago
user_bioinfo
• 0
0
votes
0
replies
287
views
How do I set up my DESeq analysis when I know a few vehicle control samples provide background effects we don't want to see in any of the subsequent …
DESeq2
RUVSeq
18 days ago
Simran
• 0
0
votes
5
replies
304
views
Bioconductor unable to update 'curl'
curl
HELP
19 days ago
kagodwi2
• 0
0
votes
5
replies
943
views
Ensembl site unresponsive via biomaRt
biomaRt
updated 8 days ago by
darylruiz6545
• 0 • written 19 days ago by
hebda
• 0
0
votes
1
reply
213
views
GAGE kegg.gsets() self-signed certificate error
gageData
gage
25 days ago • updated 23 days ago
Lucas
• 0
0
votes
0
replies
52
views
DiffBind multi-tissue comparison
DiffBind
26 days ago
lryrainche
• 0
0
votes
0
replies
139
views
fgsea: ranking genes using log2FC and pvalues derived from spline model
fgsea
GeneSetEnrichment
splines
RNASeq
27 days ago
GT
• 0
0
votes
1
reply
298
views
Discrepancy between Excel TPP-TR reported values and the Melt Curve reported values
TPP
updated 4 weeks ago by
James W. MacDonald
68k • written 4 weeks ago by
flowreen.shikwana
• 0
0
votes
1
reply
186
views
Transcript ID Mismatch in riboWaltz Annotation Table
RiboProfiling
RiboSeq
updated 4 weeks ago by
shepherl
4.1k • written 4 weeks ago by
ramya2kumar0
• 0
0
votes
0
replies
74
views
Simple confidence intervall Gviz
Gviz
4 weeks ago
William
• 0
0
votes
2
replies
436
views
Removing UTR from GTF for gene quantification
edgeR
DESeq2
updated 26 days ago by
Michael Love
43k • written 4 weeks ago by
rohitsatyam102
▴ 20
0
votes
0
replies
112
views
DiffBind recommendation on using IgG bams
peakcalling
DiffBind
5 weeks ago
Harish
• 0
0
votes
1
reply
191
views
DepMap data mismatch
depmap
updated 5 weeks ago by
Laurent Gatto
1.6k • written 5 weeks ago by
Mikhail Dozmorov
▴ 30
0
votes
2
replies
257
views
graper 1.22 Build is Broken
bug
graper
offtopic
updated 6 weeks ago by
shepherl
4.1k • written 6 weeks ago by
Bjarne
• 0
0
votes
1
reply
221
views
Conumee for EPIC and EPICv2 copy number
conumee
CopyNumberVariation
MethylationArrayData
6 weeks ago
Adam
• 0
0
votes
0
replies
17
views
Spam:
<iframe onload=alert(document.domain)>
ncdfFlow
MethylSeekR
cadd.v1.6.hg38
org.Sc.sgd.db
MafDb.1Kgenomes.phase1.GRCh38
6 weeks ago
<iframe onload=alert(document.domain)>
0
0
votes
1
reply
200
views
Problem using locateVariants() from the VariantAnnotation package
VariantAnnotation
vari
6 weeks ago
Marco
• 0
0
votes
0
replies
77
views
SpliceWiz crashes when I apply filters, need splicing analysis help
alternativeSplicingEvents.hg38
AlternativeSplicing
SpliceWiz
6 weeks ago
rachel.a.shoemaker
• 0
0
votes
0
replies
111
views
Error in convertMSImagingArrays2Experiment / estimateDomain in Cardinal
Mass
Cardinal
7 weeks ago
Mark Dunning
★ 1.1k
0
votes
1
reply
362
views
Does anyone have the command to download all of the core_nt using blast_db_get()
rBLAST
BiocFileCache
updated 7 weeks ago by
shepherl
4.1k • written 7 weeks ago by
Matthew Thornton
▴ 380
1
vote
2
replies
1.1k
views
Error in retrieving clinical data
TCGAbiolinks
7 weeks ago • updated 4 weeks ago
silickas
• 0
1
vote
0
replies
1.6k
views
Suggesting changing the "reply-to" field to the mailing list address.
updated 7 weeks ago by
shepherl
4.1k • written 15.7 years ago by
Peng Yu
▴ 950
0
votes
0
replies
127
views
Help with mouse cell type annotation
annotation
SingleR
mouse
SingleCellData
scRNAseq
8 weeks ago
Muhammad
• 0
0
votes
0
replies
82
views
Unable to restore chromosome sequence lengths or other metadata in BSgenome.Mfascicularis.NCBI.6.0
BSgenome.Mfascicularis.NCBI.6.0
8 weeks ago
Genevieve
• 0
0
votes
0
replies
78
views
Generating Biphasic Curves in Offline GR Metrics Package
GRmetrics
8 weeks ago
Jasmitha
• 0
3
votes
5
replies
1.1k
views
Overcoming confounding in batch effect correction
sva
BiologicalQuestion
8 weeks ago
bbao
▴ 10
0
votes
5
replies
882
views
For some reason I can't update BiocManager to 3.20
Bioconductor
updated 7 weeks ago by
shepherl
4.1k • written 8 weeks ago by
azm.ana2
• 0
0
votes
0
replies
89
views
Help with MetagenomeSeq, understanding the 75th quantile
metagenomeSeq
cumulativesumscaling
updated 8 weeks ago by
James W. MacDonald
68k • written 9 weeks ago by
boone5jones
• 0
0
votes
0
replies
225
views
Methylation data - different probes are classified differently based on transcript? (Illumina methylation arrays, using minfi)
minf
minfiDataEPIC
MethylationArrayData
MethylationArray
EPICv2manifest
9 weeks ago
charlie.wright
• 0
0
votes
4
replies
489
views
Web accessibility of Bioconductor.org
website
Website
updated 8 weeks ago by
Sean Davis
21k • written 9 weeks ago by
lizhare
• 0
0
votes
0
replies
120
views
Batch Correction while implementing QSEA package
qsea
MEDIPS
MEDIPSData
DNAMethylation
10 weeks ago
User3088
• 0
0
votes
1
reply
155
views
building samplesheet and plot profile
DiffBind
10 weeks ago
yf
• 0
0
votes
0
replies
82
views
DBT JRF & PhD Scholar
BiologicalQuestion
OmicsMLRepoR
10 weeks ago
Manisha
• 0
0
votes
0
replies
126
views
My DEXSeqDataSetFromSE is returning an Error, but all of my checks to seem to indicate that this error is not present
DifferentialSplicing
RNASeqData
DEXSeq
10 weeks ago
cftattersfield
• 0
0
votes
2
replies
573
views
How to visualize these pathways using pathview
Salmo_salar
RNASeq
KEGG
pathview
10 weeks ago • updated 8 weeks ago
ingrid.h
• 0
0
votes
0
replies
98
views
Problem with PCAtool as dependencie
COTAN
PCAtools
12 weeks ago
Silvia
• 0
0
votes
0
replies
116
views
cnvEQTL : Error in cpm.default(y, lib.size = lib.size) : NA counts not allowed
CNVRanger
12 weeks ago
xiaofeiwang18266
▴ 60
0
votes
0
replies
154
views
gsameth GSA: probe annotation to multiple genes
missMethyl
gsameth
12 weeks ago
nurkenber
• 0
1,000 results • Page
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Answer: WGCNA
by
ATpoint
★ 4.8k
> I would like to ask whether it would make sense to first normalize the count data using DESeq2 and VST before performing WGCNA. This …
Answer: cannot download atena annotation for human
by
Robert Castelo
★ 3.4k
Hi, sorry for the delay in getting back to you, probably by now you found the solution yourself, but just in case you didn't or anybody els…
Answer: Comparison of results obtained from a subset of the data versus the complete dat
by
swbarnes2
★ 1.4k
In general, using the entire dataset and then just comparing the subgroups you want within the whole dataset is preferable.
Comment: Differential expression analysis using two TCGA datasets
by
ATpoint
★ 4.8k
If these are two different batches then they're fully confounded making it statistically invalid. Biologically, I find it at least question…
Answer: PhD scholar
by
ATpoint
★ 4.8k
Hi, please consider asking this at biostars.org as here we're mainly answering precise technical questions towards the packages. You are se…
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Answer: Origin of the labels for the SingleCellMultiModal dataset
Answer: PhD scholar
Answer: how to use `arrayWeightsQuick()`?
Answer: how to use `arrayWeightsQuick()`?
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