Log In
Sign Up
about
faq
Ask a question
Latest
News
Jobs
Tutorials
Tags
Users
New Post
Latest
News
Jobs
Tutorials
Tags
Users
Log In
Sign Up
About
Limit
all time
today
this week
this month
this year
Unanswered
All posts
Sort
Update
Answers
Bookmarks
Creation
Replies
Rank
Views
Votes
14
votes
9
replies
15k
views
How does DESeq2 handle zero counts in one condition?
deseq2
deseq
rna-seq
9.4 years ago
gavrielmatt
▴ 30
14
votes
5
replies
41k
views
plotPCA - how to add labels to a PCA plot
plotPCA
deseq2
labels
updated 7.4 years ago by
Federico Marini
▴ 150 • written 7.4 years ago by
al-ash
▴ 50
14
votes
21
replies
11k
views
Installing ShortRead - error: zlib not found even with zlib in LD_LIBRARY_PATH
package installation
shortread
dependency
updated 5.0 years ago by
January Weiner
▴ 240 • written 6.0 years ago by
joseph.elsherbini
▴ 60
14
votes
12
replies
9.4k
views
limma lmFit coefficients and p-values
limma
methylation
ewas
updated 7.8 years ago by
Steve Lianoglou
★ 13k • written 7.8 years ago by
CPR
▴ 30
14
votes
10
replies
4.8k
views
HDF5 reading speed
rhdf5
hdf5
updated 6.3 years ago by
Mike Smith
★ 6.5k • written 6.3 years ago by
felicien.meunier
▴ 40
14
votes
1
reply
2.0k
views
it paused in line **byte-compile and prepare package for lazy loading** when install package EnsDb.Hsapiens.v75
EnsDb.Hsapiens.v75
updated 3.4 years ago by
Batool
▴ 370 • written 3.4 years ago by
YunYun
▴ 70
14
votes
9
replies
3.8k
views
Is Limma's removeBatchEffect() and log2() commutative?
limma
rna-seq
removebatcheffect()
updated 6.3 years ago by
alakatos
▴ 130 • written 8.1 years ago by
Ekarl2
▴ 80
14
votes
19
replies
8.9k
views
DESeq2 Model Design
DESeq2
linear model
model
updated 3.0 years ago by
Michael Love
42k • written 9.5 years ago by
andrew.j.skelton73
▴ 370
14
votes
8
replies
2.7k
views
News:
Bioconductor packages now each have a DOI.
doi
citation
News
updated 6.7 years ago by
Martin Morgan
25k • written 6.7 years ago by
Sean Davis
21k
14
votes
5
replies
22k
views
Dealing with genes that have Padj=NA
deseq2
updated 9 months ago by
Juan Pablo
• 0 • written 8.4 years ago by
raya.fai
▴ 60
14
votes
16
replies
2.6k
views
Limma - discrepancy in number of significant genes
limma
differential gene expression
microarray
linear model
updated 8.9 years ago by
James W. MacDonald
65k • written 8.9 years ago by
bcbio_uk
▴ 10
13
votes
10
replies
3.9k
views
Big differences in logfoldchange for some genes between edgeR and DESeq2
edger
deseq2
updated 8.5 years ago by
Gordon Smyth
50k • written 8.5 years ago by
Matarit
• 0
13
votes
6
replies
6.3k
views
goana limma- extract list of DE genes and genes in the enriched GO terms?
limma
goana
updated 8.8 years ago by
Gordon Smyth
50k • written 8.9 years ago by
carl.mann
▴ 20
13
votes
3
replies
12k
views
Understanding contrasts limma
limma
design and contrast matrix
updated 8.6 years ago by
Aaron Lun
★ 28k • written 8.6 years ago by
Andy91
▴ 60
13
votes
12
replies
6.7k
views
From a ENST to ENSG
AnnotationDbi
3.3 years ago
suxxa
▴ 20
13
votes
20
replies
14k
views
Can I feed TCGA normalized count data to EdgeR for differential gene expression analysis
EdgeR
TCGA
normalized count
updated 9.2 years ago by
alakatos
▴ 130 • written 9.2 years ago by
ycding
▴ 10
13
votes
2
replies
6.5k
views
Using limma when continuous and categorical confounders are present at the same time (e.g.age, gender)
limma
covariate
continuous
categorical
adjustment
updated 8.8 years ago by
Gordon Smyth
50k • written 8.8 years ago by
sg45653
• 0
13
votes
20
replies
3.6k
views
cellCounts() function floating point error
Rsubread
2.0 years ago • updated 21 months ago
J-E
• 0
13
votes
5
replies
7.1k
views
EDGE-R exact test vs QL F-test
edger
rnaseq
updated 2.1 years ago by
Sarah
• 0 • written 7.9 years ago by
kaihami
▴ 30
13
votes
3
replies
2.2k
views
News:
Bioconductor teaching week
teaching
Carpentries
written 21 months ago by
Laurent Gatto
1.6k
13
votes
2
replies
4.6k
views
Best method/package for Gene Set Enrichment Analysis in microarrays?
GSEA
goseq
topgo
gega
gostats
updated 8.5 years ago by
Robert Castelo
★ 3.3k • written 8.5 years ago by
jacorvar
▴ 40
13
votes
11
replies
17k
views
edgeR TMM values
edger
8.3 years ago
ribioinfo
▴ 100
13
votes
16
replies
5.0k
views
Using edgeR or DESeq2 to analyze allele-specific expression?
edgeR
deseq2
ase
allele
8.6 years ago
trianglescout
▴ 40
13
votes
8
replies
16k
views
how to use biomaRt with ensembl build 37
biomaRt
ensembl
GRCh37
updated 9.6 years ago by
Thomas Maurel
▴ 800 • written 9.6 years ago by
Pablo marin-garcia
▴ 90
13
votes
1
reply
2.9k
views
News:
Updated Bioconductor Package Submission Policy
package
submission
News
8.4 years ago
Martin Morgan
25k
13
votes
2
replies
3.1k
views
voom with combat
limma
voom
combat
batch effect
updated 7.8 years ago by
Gordon Smyth
50k • written 7.8 years ago by
eldronzhou
▴ 10
13
votes
3
replies
3.5k
views
EdgeR cpm: factor of 2 when adjusting library size?
edger
cpm
8.4 years ago
mikaelhc
▴ 20
13
votes
11
replies
12k
views
RNA-Seq, generate batch-free count matrix
edgeR
sva
updated 9.6 years ago by
Gordon Smyth
50k • written 9.8 years ago by
Brian Haas
▴ 90
13
votes
35
replies
16k
views
RDAVIDWebService Error 301: Moved Permanently
rdavidwebservice
david
updated 5.8 years ago by
gevermalc
• 0 • written 8.8 years ago by
Vivek.b
▴ 100
13
votes
6
replies
7.1k
views
DESeq2 multiple interaction terms 3-factor design
deseq2
deseq
interactions
multiple factor design
updated 8.3 years ago by
Michael Love
42k • written 8.3 years ago by
Stephen Turner
▴ 290
13
votes
1
reply
4.6k
views
WGCNA - Compare module preservation between class
WGCNA
coexpression
updated 8.8 years ago by
Peter Langfelder
★ 3.0k • written 8.8 years ago by
abellonau
▴ 60
13
votes
21
replies
6.1k
views
modeling zero-dominated RNA-seq with voom/limma and hurdle models (pscl)
limma
voom
hurdle
single cell
8.7 years ago
osa.zuta
▴ 40
13
votes
22
replies
27k
views
DESEq2 Paired samples Before and after treatment
deseq2
paired samples
updated 12 weeks ago by
Michael Love
42k • written 7.9 years ago by
adesrichard
▴ 30
12
votes
7
replies
4.1k
views
illumina ht-12 v4 expression beadchip
microarray
illumina human ht-12 v4
updated 7.2 years ago by
Gordon Smyth
50k • written 7.2 years ago by
arisarkar88
▴ 40
12
votes
15
replies
3.5k
views
error with HDF5Array
hdf5array
biocparallel
updated 6.0 years ago by
Mike Smith
★ 6.5k • written 6.0 years ago by
cath
▴ 30
12
votes
8
replies
1.9k
views
DESeq fitted values using coefficients vs mu
deseq2
updated 7.4 years ago by
Michael Love
42k • written 7.4 years ago by
Matthew McCall
▴ 830
12
votes
20
replies
2.1k
views
Possible implementation of multifactorial contrasts in limma regarding a microarray dataset
limma
multifactorial design
design and contrast matrix
affymetrix microarrays
updated 8.7 years ago by
Aaron Lun
★ 28k • written 8.7 years ago by
svlachavas
▴ 830
12
votes
3
replies
6.0k
views
Error while uploading Bioconductor packages - R Shiny
shiny
package
deploy
6.2 years ago
lloyd.izard
▴ 80
12
votes
4
replies
4.5k
views
differential expression analysis of htseq data with edgeR/voom
voom
htseq
edgeR
limma
RNASeq123
updated 5.4 years ago by
Gordon Smyth
50k • written 6.9 years ago by
wd
▴ 30
12
votes
1
reply
7.2k
views
identifying the samples on plotPCA
deseq2
plotpca
PCa
updated 6.6 years ago by
Michael Love
42k • written 6.6 years ago by
lirongrossmann
▴ 80
12
votes
7
replies
2.0k
views
No method for coercing this S4 class to a vector, as trying to import my own data rather than using SRA in the workflow RnaSeqGeneEdgeRQL
rnaseqgeneedgerql
shortread
Rsubread
updated 5.1 years ago by
Aspie96
▴ 60 • written 5.1 years ago by
Raito92
▴ 60
12
votes
9
replies
8.0k
views
Appropriate use of the function treat of the limma package
limma
treat
microarray
bioconductor
9.2 years ago
svlachavas
▴ 830
12
votes
7
replies
4.4k
views
Plot ggplot2 and ggbio Images Together
ggplot2
ggbio
cowplot
updated 4.8 years ago by
Assa Yeroslaviz
★ 1.5k • written 8.9 years ago by
andrew.j.skelton73
▴ 370
12
votes
6
replies
2.6k
views
How did the edgeR authors compute Figure 2 (genewise deviance statistics?)
edger
differential gene expression
rnaseq
updated 7.1 years ago by
Gordon Smyth
50k • written 7.1 years ago by
gabriel.rosser
▴ 20
12
votes
11
replies
4.2k
views
Memory usage for bplapply -- is the entire environment copied over to each worker thread?
bplapply
biocparallel
deseq2
updated 8.8 years ago by
Valerie Obenchain
★ 6.8k • written 8.8 years ago by
Lauren
▴ 40
12
votes
6
replies
21k
views
DESEq2 comparison with mulitple cell types under 2 conditions
deseq2
multiple factor design
updated 9.0 years ago by
Michael Love
42k • written 9.0 years ago by
kmu004
▴ 50
12
votes
12
replies
2.1k
views
FDR does not change between genes in edgeR
RNAseq
edgeR
updated 5.4 years ago by
Gordon Smyth
50k • written 5.4 years ago by
apfelbapfel
▴ 30
12
votes
33
replies
29k
views
Cannot install packages by BiocManager::install()
BiocManager
updated 2.1 years ago by
James W. MacDonald
65k • written 3.0 years ago by
mizzle
▴ 60
12
votes
9
replies
3.3k
views
Limma residuals matrix
limma
updated 4.8 years ago by
Gordon Smyth
50k • written 4.8 years ago by
agustin.gonvi
▴ 20
12
votes
15
replies
15k
views
WGCNA: Understanding module-trait correlations
wgcna package
updated 5.8 years ago by
Peter Langfelder
★ 3.0k • written 5.8 years ago by
bekah
▴ 40
1,000 results • Page
3 of 20
Recent ...
Replies
Comment: Numerical differences in DESeq2 output depending on different design matrix cons
by
JKim
• 0
The 1st model has an interaction term, but the 2nd model doesn't have the interaction term. That makes the difference.
Comment: Ensembl plants at annotationHub?
by
Daniele
• 0
Hi, I'm using Ensembl Plants release 59 with the IWGSC RefSeq v1.1 gene annotation. Thanks a lot for replying so quickly!
Comment: Numerical differences in DESeq2 output depending on different design matrix cons
by
swbarnes2
★ 1.4k
If you restrict yourself to, say, genes with a baseMean > 50, are the numerical differences between the two designs significant?
Comment: DESeq2- Mysterious interaction suppresses DEGs
by
shaunpeterson
• 0
The images I tried to attach didn't attach. Here is the PCA (MDS) of all the samples, with the Cortex outlier highlighed. ![enter image de…
Comment: STRINGdb : error with string_db$plot_network()
by
damian.szk
▴ 80
ok. Forcing non-secure protocol should not be needed anymore, due to changes in the underlying library. However, I will look at why "HTTP" …
Votes
Answer: Error while installing BiocManager::install("org.Vdahliae.eg.db")
Comment: How can I create a eigencorplot of pca created from deseq2 object with PCAtools
Answer: Importing a GraphNEL into Cytoscape with RCy3 with error: "Error in cyrestPUT(pa
Answer: Importing a GraphNEL into Cytoscape with RCy3 with error: "Error in cyrestPUT(pa
Rsubread counting peaks ATACseq
Awards
• All
Popular Question
to
Vincent J. Carey, Jr.
6.7k
Popular Question
to
Koen Van den Berge
▴ 180
Popular Question
to
shepherl
3.9k
Popular Question
to
Ken C
• 0
Popular Question
to
Johannes Rainer
★ 2.0k
Locations
• All
India,
20 minutes ago
United States,
43 minutes ago
WEHI, Melbourne, Australia,
54 minutes ago
Melbourne, Australia,
55 minutes ago
The city by the bay,
1 hour ago
Traffic: 381 users visited in the last hour
Content
Search
Users
Tags
Badges
Help
About
FAQ
Access
RSS
API
Stats
Use of this site constitutes acceptance of our
User Agreement and Privacy Policy
.
Powered by the
version 2.3.6