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SVA
•
reset
0
votes
0
replies
1.4k
views
Surrogate variable, celltype composition correction and overfitting in DNA methylation data
sva
limma
methylation
MethylationArray
5.0 years ago
epibio
▴ 10
1
vote
8
replies
2.3k
views
Error in running Combat function
sva
ComBat
updated 5.0 years ago by
Kevin Blighe
★ 4.0k • written 5.0 years ago by
Reza
▴ 10
0
votes
5
replies
1.9k
views
Variable of interest in combat correction
sva
combat
updated 5.2 years ago by
James W. MacDonald
68k • written 5.2 years ago by
ch_el
▴ 10
0
votes
3
replies
1.7k
views
Extracting a subset of samples following SVA
Combat
SVA
Limma
updated 5.3 years ago by
Kevin Blighe
★ 4.0k • written 5.3 years ago by
jonellevillar
• 0
0
votes
10
replies
2.0k
views
Running SVA changes format of time variable in model
sva
proxitct
hms
updated 5.4 years ago by
James W. MacDonald
68k • written 5.4 years ago by
jonellevillar
• 0
7
votes
6
replies
3.2k
views
sva ComBat implementation for multiple sources of batch effects
sva
combat
batch-adjustment
updated 5.7 years ago by
W. Evan Johnson
▴ 870 • written 5.7 years ago by
Zach Roe
▴ 10
0
votes
1
reply
1.2k
views
SVA for visualisation purposes
sva
svaseq
surrogate variable analysis
updated 5.8 years ago by
James W. MacDonald
68k • written 5.8 years ago by
Mozart
▴ 30
0
votes
1
reply
1.4k
views
Adjusting for unwanted variation in DESeq2
DESeq2
deseq2
sva
rna-seq
differential expression anlaysis
updated 5.9 years ago by
James W. MacDonald
68k • written 5.9 years ago by
Nikolay Ivanov
• 0
1
vote
1
reply
1.5k
views
SVA paired samples
SVA
EPIC
methylation
limma
updated 5.9 years ago by
James W. MacDonald
68k • written 5.9 years ago by
whyw6948
• 0
2
votes
4
replies
1.7k
views
DESeq2 - problem with inferring correct results.
deseq2
rnaseq
sva
fdrtool
ihw
updated 5.9 years ago by
Michael Love
43k • written 5.9 years ago by
rihards.saksis
• 0
1
vote
2
replies
1.5k
views
Validity of duplicateCorrelation after ComBat in this scenario
limma
ComBat
SVA
updated 6.0 years ago by
Gordon Smyth
53k • written 6.0 years ago by
vizio12341337
• 0
0
votes
0
replies
3.0k
views
adjusting for batch using ComBat (sva) - singularity error
microarray
combat
sva
batch effects
6.0 years ago
anne.bozack
• 0
0
votes
1
reply
1.4k
views
problem for interpretation of resulted ComBat() plot
ComBat
sva
batch effect
RNA-seq
updated 6.1 years ago by
W. Evan Johnson
▴ 870 • written 6.1 years ago by
modarzi
▴ 10
0
votes
0
replies
1.2k
views
limma-voom group design and its effect on sva
limma
voom
group-design
sva
6.1 years ago
kentfung
▴ 20
0
votes
8
replies
2.2k
views
Error in sva() function: missing values, NaNs produced
sva
batch-correction
updated 6.2 years ago by
James W. MacDonald
68k • written 6.2 years ago by
thkapell
▴ 10
0
votes
3
replies
1.5k
views
In SVA, the percent of biological variable of interest didnot change after adding SV1
SVA
combat
r
microarray
covariates
updated 6.2 years ago by
Martin Morgan
25k • written 6.2 years ago by
dhwani2410
• 0
2
votes
5
replies
2.3k
views
SVA for repeated measures design
SVA
deseq2
repeated measures
updated 6.3 years ago by
Robert Castelo
★ 3.4k • written 6.3 years ago by
sara.blocquiaux
• 0
0
votes
1
reply
1.6k
views
Handling adjustment variables and surrogate variables in model
sva
deseq2
updated 6.3 years ago by
James W. MacDonald
68k • written 6.3 years ago by
rbutler
• 0
1
vote
1
reply
1.8k
views
Bioconductor SVA: two variables of interest
sva
updated 6.4 years ago by
James W. MacDonald
68k • written 6.4 years ago by
sara.blocquiaux
• 0
4
votes
5
replies
1.5k
views
Design matrix with intercept for multiple cluster comparison
limma
sva
updated 6.4 years ago by
centralmenu10
• 0 • written 6.4 years ago by
kentfung
▴ 20
0
votes
2
replies
1.8k
views
Analyzing a RNA-Seq dataset with paired samples and 2 batches
deseq2
sva
combat
updated 6.4 years ago by
Michael Love
43k • written 6.4 years ago by
ege.dedeoglu
• 0
0
votes
3
replies
1.4k
views
Design matrix for cohort with samples outside "block"
limma
voom
sva
6.4 years ago
kentfung
▴ 20
0
votes
0
replies
833
views
fsva function does not work without newdat argument
sva
6.4 years ago
jakob.wirbel
• 0
0
votes
0
replies
1.2k
views
The correct specification of the model matrix to ComBat
ComBat
sva
6.4 years ago
Sam
▴ 10
8
votes
4
replies
5.5k
views
correcting the batch effects in Limma and SVA
limma
combat
sva
updated 6.5 years ago by
Gordon Smyth
53k • written 6.5 years ago by
Bogdan
▴ 670
0
votes
0
replies
1.4k
views
Including sva results in SeqGSEA with data with batch effect
limma
deseq2
seqgsea
sva
deseq
6.5 years ago
kentfung
▴ 20
1
vote
1
reply
2.2k
views
Using surrogate variables as covariates in WGBS differential methylation calling
dmrseq
sva
DSS
updated 6.6 years ago by
keegan
▴ 60 • written 6.6 years ago by
gjl
▴ 10
2
votes
8
replies
4.4k
views
removing batch effect using DESeq and sva
sva
deseq2
batch effect
PCA
heatmap
updated 6.6 years ago by
Michael Love
43k • written 6.6 years ago by
bioyas
▴ 10
2
votes
1
reply
2.2k
views
Using SVA (surrogate variable analysis) to correct for 'completely' confounded cell type composition in DNA methylation data
sva
linear model
cell type composition
R
microarray
6.6 years ago
epibio
▴ 10
5
votes
3
replies
3.3k
views
Adjusting for known covariates before coexpression analysis with WGCNA
wgcna
coexpression
sva
updated 6.7 years ago by
Peter Langfelder
★ 3.0k • written 6.7 years ago by
mikhael.manurung
▴ 280
0
votes
1
reply
1.2k
views
DESeq2, how to deal with batch effect: t-test or design matrix?
deseq2
batch
sva
t-test
design matrix
updated 6.7 years ago by
Michael Love
43k • written 6.7 years ago by
Mozart
▴ 30
3
votes
12
replies
5.2k
views
ComBat normalization for batch effect change 0 values
ComBat
batch effect
sva
normalization
updated 6.7 years ago by
James W. MacDonald
68k • written 6.7 years ago by
hackingfactory
▴ 10
1
vote
1
reply
1.4k
views
svaseq - over adjustment
svaseq
sva
6.8 years ago
flippy23
• 0
2
votes
17
replies
3.9k
views
Computationally Singular Matrices - DESeq
deseq2
rnaseq
sva
updated 3.2 years ago by
Michael Love
43k • written 6.8 years ago by
flippy23
• 0
1
vote
2
replies
2.1k
views
Normalized transcript/exon counts for network analysis
drimseq
dexseq
wgcna
sva
updated 6.9 years ago by
Gosia Nowicka
▴ 90 • written 6.9 years ago by
maya.kappil
▴ 30
4
votes
4
replies
3.2k
views
RNA-seq batch correction using technical replicates profiled across batches
deseq2
ruvseq
sva
edger
limma
updated 6.9 years ago by
Gordon Smyth
53k • written 6.9 years ago by
enricoferrero
▴ 680
0
votes
0
replies
1.7k
views
OpenBLAS issue with ComBat() function of the R SVA package on Torque cluster
sva
R
OpenBLAS
updated 6.9 years ago by
James W. MacDonald
68k • written 6.9 years ago by
davide.chicco
• 0
1
vote
1
reply
1.2k
views
sva correction for MEDIPS
MEDIPS
svaseq
sva
updated 7.0 years ago by
Lukas Chavez
▴ 570 • written 7.0 years ago by
tofukaj
• 0
1
vote
7
replies
2.0k
views
paired sample - SVA model matrix
limma
sva
paired sample
updated 7.1 years ago by
James W. MacDonald
68k • written 7.1 years ago by
flippy23
• 0
1
vote
1
reply
1.5k
views
Define batch effect variables before removing them or getting rid of hidden surrogate variables
batch effect correction
sva
proteomics
7.2 years ago
Sebastian Hesse
▴ 70
1
vote
10
replies
8.4k
views
SVAseq and DESeq2 workflow
sva
deseq2
updated 7.2 years ago by
Michael Love
43k • written 7.2 years ago by
capricygcapricyg
▴ 10
0
votes
0
replies
768
views
Sva for tumor cellular heterogeneity
limma
sva
7.3 years ago
chp950
• 0
0
votes
2
replies
2.1k
views
DESeq2 batch correction and possible ComBat/SVA over-correction of RNA-seq data
deseq2
combat
sva
rna-seq
updated 7.3 years ago by
Michael Love
43k • written 7.3 years ago by
grimmerucsf
• 0
0
votes
0
replies
1.4k
views
ComBat covariate bias when building centroid based predictors
combat
combat sva
pamr
limma design matrix
sva
7.4 years ago
jmsendoya
• 0
0
votes
1
reply
2.7k
views
A problem in using Combat
sva
combat
updated 7.6 years ago by
W. Evan Johnson
▴ 870 • written 7.6 years ago by
linw
• 0
3
votes
4
replies
2.2k
views
Calling svaseq() multiple times
edger
sva
svaseq
limma
updated 7.7 years ago by
Ryan C. Thompson
★ 7.9k • written 7.7 years ago by
cats_dogs
▴ 20
1
vote
6
replies
1.9k
views
differential expression analysis with big dataset and >500 surrogate variables
SVA
deseq2
differential expression
LRT
7.7 years ago
aec
▴ 90
4
votes
8
replies
8.1k
views
Convert Normalized RNA-Seq counts to TPM after Batch Correction
sva
deseq2
limma
updated 3.4 years ago by
eve.olszanowski
• 0 • written 7.8 years ago by
rrcutler
▴ 70
3
votes
7
replies
6.6k
views
What does this error mean? - issue implementing SVA
sva
rna-seq
updated 7.8 years ago by
Sandip Darji
▴ 30 • written 9.9 years ago by
kmuench
▴ 40
8
votes
3
replies
6.0k
views
DESeq2 with interaction using SVA
deseq2
sva
interaction term
grouping variable
deseq
8.0 years ago
kevin.kingsland
▴ 70
241 results • Page
2 of 5
Recent ...
Replies
Answer: When to use edgeR or limma
by
Gordon Smyth
53k
The short answer is that we generally prefer edgeR for applications with lots of small counts and limma for complex designs with random eff…
Comment: limpa-blank normalization and Spectronaut's PTM stoichiometry
by
Gordon Smyth
53k
I updated the above answer today.
Answer: When to use edgeR or limma
by
James W. MacDonald
68k
I would use edgeR's quasi-likelihood model for any analysis with a smaller number of observations (like 3 vs 3 or similar), but if you have…
Answer: limpa-blank normalization and Spectronaut's PTM stoichiometry
by
Gordon Smyth
53k
The short answer is that limpa reads standard feature-level intensities from Spectronaut or other quantifications tools. limpa is designed …
Comment: Question about the filterByExpr function inputs in edgeR
by
mohammedtoufiq91
▴ 10
@gordonsmyth Noted, thank you very much.
Votes
Answer: When to use edgeR or limma
Answer: When to use edgeR or limma
Answer: When to use edgeR or limma
A: deseq2 - paired samples in 2 sequencing types with very different library sizes
Comment: Question about the filterByExpr function inputs in edgeR
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