Log In
Sign Up
about
faq
Ask a question
Latest
News
Jobs
Tutorials
Tags
Users
New Post
Latest
News
Jobs
Tutorials
Tags
Users
Log In
Sign Up
About
Limit
all time
today
this week
this month
this year
Unanswered
All posts
Sort
Update
Answers
Bookmarks
Creation
Replies
Rank
Views
Votes
0
votes
2
replies
2.8k
views
calculateQCMetrics defunct, how to calculate the quality metrics by perCellQCMetrics
scRNAseq
updated 3.6 years ago by
ATpoint
★ 5.0k • written 3.6 years ago by
otieno43
• 0
0
votes
1
reply
4.9k
views
Cannot Install WGCNA
Bioconductor
updated 3.6 years ago by
shepherl
4.3k • written 3.6 years ago by
pthom010
• 0
3
votes
4
replies
3.8k
views
Why Negative value from GSVA
GSVA
RNASeq
edgeR
3.6 years ago • updated 3.5 years ago
Yang Shi
▴ 10
1
vote
3
replies
1.4k
views
Low Differentially Bound Sites found with DiffBind
Cut&Run
DiffBind
3.6 years ago • updated 3.5 years ago
gannoncottone
• 0
0
votes
0
replies
654
views
regulondb version fixed to 10.8?
regutools
3.6 years ago
a.giachino2
• 0
0
votes
1
reply
2.2k
views
Diffbind analysis of ATAC-seq data
ATACSeq
DiffBind
updated 3.6 years ago by
Rory Stark
★ 5.2k • written 3.6 years ago by
young
• 0
0
votes
3
replies
6.9k
views
Unable to generate a dotplot to view the enrichment analysis results (clusterProfiler/ enrichplot)
clusterProfiler
enrichplot
clusterpro
doseR
dose
updated 3.5 years ago by
Guido Hooiveld
★ 4.1k • written 3.6 years ago by
rama
▴ 10
1
vote
1
reply
833
views
how do singleton samples contribute to dispersion estimate in DESeq2?
DESeq2
updated 3.6 years ago by
Michael Love
43k • written 3.6 years ago by
Victor
▴ 10
0
votes
3
replies
4.0k
views
Should 0 values for gene counts be removed prior to ssGSEA/GSVA analysis?
GSEA
GSVA
updated 3.2 years ago by
rocanja
▴ 60 • written 3.6 years ago by
João
• 0
1
vote
4
replies
7.2k
views
Error message: Could not find function "DESeqDataSetFromMatrix"
DESeq2
3.6 years ago • updated 3.5 years ago
Md. Faridul
• 0
0
votes
0
replies
1.1k
views
How to create consensus network from SampledBlockwiseModules in WGCNA?
NetworkInference
SampledBlockWiseModules
WGCNA
3.6 years ago
as8020
• 0
0
votes
1
reply
1.3k
views
fetaure counts err
featurecounts
updated 3.5 years ago by
Wei Shi
★ 3.6k • written 3.6 years ago by
哲
• 0
0
votes
2
replies
1.5k
views
Seeking help in multifactor differential gene expression analysis using DESeq2. Can not get significance difference while comparing 3 time factor (…
DifferentialExpression
GeneExpression
R
enrichment
DEGseq
updated 3.6 years ago by
swbarnes2
★ 1.4k • written 3.6 years ago by
ac.mainul.mmb
• 0
0
votes
1
reply
2.0k
views
bioMart Sscrofa_gene_ensembl getBM() paralogues ERROR
biomaRt
ensembldb
paralogues
updated 3.6 years ago by
Malcolm Cook
★ 1.6k • written 3.6 years ago by
Zeroual
• 0
0
votes
0
replies
1.2k
views
ACMG Annotations for Variants in R
ACMG
SNP
3.6 years ago
hamza_karakurt
▴ 60
0
votes
3
replies
4.7k
views
Can't Install ensembldb and EnsDb.Hsapiens.v86
installation
EnsDb.Hsapiens.v86
Bioconductor
package
ensembldb
3.6 years ago
elmfinds
• 0
0
votes
2
replies
1.3k
views
Number of rows in DESeq2 output (.csv) is not the same as number of rows in the results(dds) dataframe
output
difference
3.6 years ago
Jamie
• 0
0
votes
0
replies
1.1k
views
News:
Translation Hackathon (community event) announcement
event
translation
community
3.6 years ago
kozo.nishida
• 0
1
vote
6
replies
2.0k
views
Error while running DESeq2
DifferentialExpression
3.6 years ago
srikar
• 0
1
vote
0
replies
1.0k
views
Mapping patient dataset onto control dataset
Cytometry
R
Data
3.6 years ago
hamiltond
▴ 10
0
votes
4
replies
1.7k
views
rename phenotypic variables in pData (microarray) or colData (RNA-Seq)
PhenoGeneRanker
3.6 years ago • updated 3.5 years ago
jogugil
• 0
0
votes
1
reply
822
views
Error
DESeq2
updated 3.6 years ago by
ATpoint
★ 5.0k • written 3.6 years ago by
Mahsa
• 0
2
votes
8
replies
5.2k
views
How to get DESeq2 results for a list of genes
DESeq2
3.6 years ago
Lucía
▴ 30
0
votes
0
replies
958
views
nearest and nearestKNeighbors with k=1 produce different results
GenomicRanges
3.6 years ago
Simon Coetzee
▴ 50
2
votes
2
replies
4.3k
views
ComplexHeatmap: Change font size of annotation axis values
ComplexHeatmap
updated 2.5 years ago by
franciscaelibethgalvez
• 0 • written 3.6 years ago by
nalaspina
▴ 10
1
vote
1
reply
1.4k
views
setting sizeFactors from scran :: caculateSumFactors.
scran
DESeq2
updated 3.6 years ago by
ATpoint
★ 5.0k • written 3.6 years ago by
OE
• 0
1
vote
2
replies
6.2k
views
Unable to open hd5 file using rhdf5 but can list contents
hdf5
h5
rhdf5
updated 3.6 years ago by
Mike Smith
★ 6.6k • written 3.6 years ago by
dNand
• 0
2
votes
3
replies
3.3k
views
Combine GRanges(List) to a single GRanges with unified breakpoints
GenomicRanges
plyranges
3.6 years ago
Rodrigo
• 0
5
votes
5
replies
3.7k
views
package 'BiocInstaller' is not available (for R version 3.4.4)
BiocInstaller
updated 3.6 years ago by
James W. MacDonald
68k • written 3.6 years ago by
Kevin
• 0
2
votes
6
replies
2.1k
views
Limma beta coefficient confidence intervals
limma
limmaGUI
beta
3.6 years ago
fluentin44
• 0
5
votes
8
replies
29k
views
Confused about the CPM and TMM normalization in edgeR
RNASeq
R
edgeR
updated 17 months ago by
Ahdee
▴ 60 • written 3.6 years ago by
Mohamed
▴ 30
0
votes
4
replies
2.0k
views
Alternative for wininet method in tximeta
DESeq2
tximport
tximportData
tximeta
3.6 years ago
uhlkatie
• 0
0
votes
4
replies
2.1k
views
how to get the gene set from online GO database
clusterProfiler
WebGestalR
3.6 years ago • updated 3.5 years ago
pengmin.wang.1
• 0
0
votes
0
replies
818
views
coseq does not find object "cap"
coseq
3.6 years ago
JaneDoe
• 0
0
votes
1
reply
5.0k
views
Pick some clusters to run trajectory and pseudotime analysis on Monocle3
SpecificClusters
TrajectoryAnalysis
PseudotimeAnalysis
Monocle3
updated 2.8 years ago by
mzh
• 0 • written 3.6 years ago by
martacrespi7
▴ 10
0
votes
0
replies
1.3k
views
Calculating tumour purity having only CNA data
PureCN
CNA
purity
cancer
3.6 years ago
JAcky
• 0
0
votes
2
replies
1.0k
views
bootstrapNullAlternativeModel() returns error
TPP2D
3.6 years ago
Tobias
▴ 40
0
votes
1
reply
1.9k
views
During dba(sampleSheet = "samples.csv") step, Error in mergeScores(merged, def, peakset, TRUE) : Not compatible with requested type: [type=charac…
DiffBind
updated 3.6 years ago by
Rory Stark
★ 5.2k • written 3.6 years ago by
niimabear
• 0
0
votes
1
reply
1.3k
views
Compare different cell lines with tissues using limma
limma
MicroarrayData
Microarray
Agilent
updated 3.6 years ago by
Gordon Smyth
53k • written 3.6 years ago by
Sam
• 0
0
votes
1
reply
1.0k
views
Error "DESeqDataSetFromMatrix" function not found
GeneExpression
updated 3.6 years ago by
Basti
▴ 780 • written 3.6 years ago by
Iraide
• 0
0
votes
1
reply
1.8k
views
Can´t install GenomicRanges and rtracklayer
rtracklayer
GenomicRanges
Installation
updated 3.6 years ago by
James W. MacDonald
68k • written 3.6 years ago by
Johanna
• 0
1
vote
1
reply
1.7k
views
How fix lines of dendrogram that overlap in the column portion of a heatmap?
heat
heatmaps
updated 3.6 years ago by
James W. MacDonald
68k • written 3.6 years ago by
MauriAndres
• 0
0
votes
0
replies
1.0k
views
set.seed in function vs clusterSetRNGStream: switching from one to another
parallel
seed
3.6 years ago
ZheFrench
▴ 60
3
votes
2
replies
3.0k
views
FeaturePlot in scater
scater
OSCA
3.6 years ago
Guandong Shang
▴ 40
0
votes
3
replies
2.4k
views
How can i fix this problem in R
S4Vectors
DESeq2
updated 3.6 years ago by
ATpoint
★ 5.0k • written 3.6 years ago by
Habib
• 0
0
votes
1
reply
1.6k
views
Use of Scater for QC in scRNA-seq: How to remove cells with less than certain number of genes supported with certain number of reads
SingleCellExperiment
updated 3.6 years ago by
ATpoint
★ 5.0k • written 3.6 years ago by
otieno43
• 0
0
votes
0
replies
1.5k
views
Problem with "TxDb.Mmusculus.UCSC.mm39.refGene" to annotate genes with ChIPseeker
TxDb.Mmusculus.UCSC.mm39.refGene
ChIPseeker
annotate
3.6 years ago
Palmira
• 0
0
votes
2
replies
6.3k
views
What is the significance of "Zero Cross" in Ranked List Metric in Gene Set Enrichment Analysis ?
GSEA
GeneSetEnrichment
3.6 years ago
Bhavana
• 0
0
votes
1
reply
1.2k
views
What are the data values in qRT-PCR for statistical testing? dCT? or 2^-dCT?
qRT-PCR
CTvalue
updated 3.6 years ago by
James W. MacDonald
68k • written 3.6 years ago by
Wendy
▴ 10
0
votes
1
reply
1.9k
views
Error: DESeq(dds , useT = TRUE, minmu = 1e-06, test = "LRT", : likelihood ratio test requires a 'reduced' design, see ?DESeq
scRNAseq
DESeq2
updated 3.6 years ago by
ATpoint
★ 5.0k • written 3.6 years ago by
abdi.zhr26
• 0
46,730 results • Page
84 of 935
Recent ...
Replies
Comment: Making a Full Rank Model for Allele-Specific Expression with DESeq2
by
Michael Love
43k
Yes, so for one thing, note that Gordon has provided code for doing what you are asking in edgeR, which you can go ahead and use. You aske…
Comment: Making a Full Rank Model for Allele-Specific Expression with DESeq2
by
chp265
• 0
I don't think DESeq2 has the ability to do multi-contrast comparisons, at least based on what I can understand of the manual; I can pick mu…
Comment: Upcoming Ensembl API and data access changes - new blog post available
by
Hugo Gruson
• 0
Thanks for the update. To be very explicit: what is going to happen to the Biomart service, on which the biomaRt bioconductor package relie…
Comment: Are individual-mouse-based statistics possible in CellChat?
by
LillianaVolkman99
• 0
thank you very much. https://www.biostars.org/p/9617271/
Comment: Making a Full Rank Model for Allele-Specific Expression with DESeq2
by
Gordon Smyth
53k
My apologies, I forgot that `design.group` is not included in the final matrix, because the baseline group effects are already captured by …
Votes
A: DESeq2: Is it possible to convert read counts to expression values via TPM and r
A: Filtering read counts matrix: how to deal with duplicated gene symbols, differen
Comment: limpa analysis advice
Answer: When to use edgeR or limma
Answer: When to use edgeR or limma
Awards
• All
Popular Question
to
ATpoint
★ 5.0k
Popular Question
to
Martin Morgan
25k
Teacher
to
Michael Love
43k
Popular Question
to
A
• 0
Popular Question
to
Lluís Revilla Sancho
▴ 760
Locations
• All
WEHI, Melbourne, Australia,
10 minutes ago
United States,
1 hour ago
United States,
1 hour ago
United States,
1 hour ago
United States,
2 hours ago
Traffic: 1258 users visited in the last hour
Content
Search
Users
Tags
Badges
Help
About
FAQ
Access
RSS
API
Stats
Use of this site constitutes acceptance of our
User Agreement and Privacy Policy
.
Powered by the
version 2.3.6