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2
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2
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1.1k
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limma for gene expression analysis with big and unbalanced sample size
limma microarray statistics
updated 4 days ago by • 0 • written 7.9 years ago by • 0
0
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0
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191
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Job: Statistics Lectureships at St Andrews
JobPosting computational statistics
10 weeks ago Andy Lynch ▴ 120
0
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0
replies
234
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multipollutant models
statistics Regression r limma
5 months ago Jitendra ▴ 10
0
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1
reply
324
views
DEseq2 : Complex design with a mixture of male and female mice
statistics DESeq2
updated 5 months ago by 41k • written 5 months ago by • 0
25
votes
7
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11k
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Effect of lfcThreshold on p-value in DESeq2
deseq2 rnaseq statistics
updated 7 months ago by ▴ 10 • written 6.6 years ago by ▴ 30
1
vote
1
reply
363
views
Further analysis after limma regression output
statistics Epigenetics limma
updated 7 months ago by 65k • written 7 months ago by ▴ 10
1
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1
reply
1.3k
views
FPKM t-test vs DEseq2
DESeq2 statistics rna-seq
updated 12 months ago by ★ 4.1k • written 12 months ago by • 0
1
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6
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2.8k
views
DESeq2 unbalanced sample size
deseq2 bioconductor bioinformatics statistics
updated 14 months ago by 41k • written 5.4 years ago by • 0
0
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3
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950
views
batch effect in EPIC array data
statistics Epigenetics R
updated 14 months ago by ▴ 730 • written 14 months ago by ▴ 10
0
votes
2
replies
1.0k
views
News: Ascona Workshop “Biological systems: from first principles to data-​driven modelling and back” 27. 3. - 1. 4. 2022
theory modeling statistics ascona Workshop
2.5 years ago • updated 15 months ago Wolfgang Huber ★ 13k
0
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0
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660
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Job: PhD position in Bioinformatics in Jena
Statistics ComputationalBiology Aging MachineLearning
16 months ago alena.vanboemmel • 0
0
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2
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694
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Results analysis of differential gene expression using DESeq2 package
RnaSeqSampleSize statistics DESeq2
updated 16 months ago by ★ 1.3k • written 17 months ago by • 0
1
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0
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645
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Statistical test for genomic annotation by ChIPseeker
statistics PeakAnnotation ChIPseeker GuangchuangYu
21 months ago arisarkar88 ▴ 40
1
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0
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774
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Job: Lecturer in Statistics - School of Mathematics and Statistics - University of St Andrews
computational teaching statistics research
21 months ago Andy Lynch ▴ 120
1
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0
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760
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Job: Research Fellow in Prostate Cancer Proteomics (Bioinformatics/Stats/Data Analysis) - University of St Andrews
Multiomics Proteomics Cancer Statistics Bioinformatics
21 months ago Andy Lynch ▴ 120
0
votes
6
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1.3k
views
regression analysis for epic array methylation data using limma
limma Epigenetics STATISTICS R
23 months ago Jitendra ▴ 10
0
votes
3
replies
1.5k
views
Reading large file (15GB) in R
R Rstudio Bioconducter statistics
updated 2.2 years ago by 21k • written 2.3 years ago by ▴ 10
3
votes
5
replies
1.4k
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P adjusted values in Deseq2
DESeq2 Statistics
written 3.3 years ago by • 0
0
votes
0
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918
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Job: Biostatistics/Bioinformatics Research Scientist at UNC Charlotte
singlecellRNA-Seq pathview statistics R
3.1 years ago • updated 3.0 years ago Luo Weijun ★ 1.6k
0
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0
replies
922
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Job: Biostatistics/Bioinformatics Research Scientist at UNC Charlotte
R statistics pathview singlecellRNA-Seq
3.4 years ago • updated 3.1 years ago Luo Weijun ★ 1.6k
10
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14
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13k
views
how DESeq calculates p-value ?
deseq differential gene expression statistics p-value
updated 3.2 years ago by ▴ 20 • written 8.2 years ago by ▴ 30
0
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0
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941
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Job: Bioinformatician at MiroBio, Oxford, UK
Transcriptomics Bioconductor Statistics Job Biocon
3.2 years ago m.jackson • 0
0
votes
0
replies
897
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Job: Scientist/Senior Scientist, Statistical Geneticist
Sequencing Genetics GeneticsPed statistics
3.3 years ago António Miguel de Jesus Domingues ▴ 510
0
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0
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1.1k
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Job: Proteomics Bioinformatician
JobPosting Proteomics Statistics Job
3.4 years ago Laura • 0
0
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0
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1.9k
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Job: Postdoc and PhD student in Bioinformatics/Biostatistics
genomics NGS R genetics statistics
5.8 years ago • updated 3.4 years ago Luo Weijun ★ 1.6k
0
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0
replies
764
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Job: Two Bioinformatics Fellowship Positions at US EPA
bioinformatics toxicology Job sequenicng statistics
3.8 years ago • updated 3.5 years ago whduke • 0
1
vote
2
replies
1.1k
views
Re-calculation of Padj (P adjusted value)
statistics Benjamini–Hochberg procedure deseq2
updated 3.6 years ago by 41k • written 3.6 years ago by ▴ 60
2
votes
0
replies
857
views
Job: Multiple open positions in biomedical statistics at Eurac Research, Italy
epidemiology statistics bioinformatics Job
3.6 years ago Johannes Rainer ★ 2.0k
1
vote
0
replies
892
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Job: Post-Doctoral Research Fellow, Cancer Genomics
genomics seattle bioinformatics data science statistics Job
3.9 years ago Fred Hutch (Recruiting) ▴ 40
3
votes
0
replies
2.2k
views
Job: Postdoctoral Scientist, Statistical Bioinformatics and Proteomics, WEHI Australia
job proteomics Job statistics
4.5 years ago • updated 4.3 years ago Gordon Smyth 50k
0
votes
0
replies
1.3k
views
Job: Postdoc and PhD student in Bioinformatics/Biostatistics
NGS R statistics genomics big data Job
5.2 years ago • updated 4.4 years ago Luo Weijun ★ 1.6k
0
votes
1
reply
784
views
How to handle batch effect and interaction with experimental variables
deseq2 statistics differential expression
4.5 years ago A • 0
0
votes
1
reply
763
views
Exclude interaction terms from the design
deseq2 statistics modelling
updated 4.5 years ago by 41k • written 4.5 years ago by • 0
2
votes
2
replies
2.9k
views
How adjusted p-values are calculated in limma
limma r transcriptomics FDR statistics
updated 4.6 years ago by 50k • written 4.6 years ago by ▴ 10
0
votes
0
replies
1000
views
Proteomics data analysis with DEP no replicates
DEP Proteomics Statistics limma
4.7 years ago tatabox • 0
3
votes
3
replies
1.4k
views
Using alternative LFC shrinkage methods for computing p-values in DESeq2
deseq2 apeglm statistics
updated 4.9 years ago by 41k • written 4.9 years ago by • 0
0
votes
1
reply
978
views
Efficient resampling in GENESIS or another Bioconductor GWAS package to obtain empirical p-values?
GENESIS GWAS resampling resample statistics
5.2 years ago naglemi ▴ 10
0
votes
0
replies
765
views
package for mismatch distribution?
genetics statistics
5.3 years ago myriam.croze07 • 0
1
vote
2
replies
939
views
Newbie to all of this
bioconductor statistics
5.5 years ago sportwoo • 0
8
votes
8
replies
6.8k
views
Voom transformation from counts and normalization to negative values
rnaseq voom limma tcga statistics
updated 5.6 years ago by ★ 7.9k • written 5.6 years ago by ▴ 60
1
vote
2
replies
964
views
What to do with microarray probes that catch multiple genes?
affymetrix microarrays microarray probe statistics
updated 5.7 years ago by 65k • written 5.7 years ago by • 0
1
vote
4
replies
1.2k
views
Do the gene set statistics of the ROAST paper correspond to those implemented in the .roastEffects R function?
limma roast statistics source code gene set testing
5.7 years ago Andrea Carenzo • 0
0
votes
2
replies
1.1k
views
comparing two GOstats result lists
gostats statistics
updated 5.9 years ago by 65k • written 5.9 years ago by ▴ 20
1
vote
0
replies
1.2k
views
Job: Statistical Research Associate
biostatistics statistics sas git assay Job
6.0 years ago Fred Hutch (Recruiting) ▴ 40
0
votes
0
replies
1.2k
views
DSS DMLTest Prior Estimate of theta dispersion
DSS dmltest bayesian statistics methylation
6.1 years ago floriandeckert ▴ 30
0
votes
0
replies
1.1k
views
News: SCANGEN: Single-cell cancer genomics workshop at ISMB 2018
single cell cancer genomics statistics News
6.1 years ago kieranrcampbell ▴ 50
0
votes
0
replies
1.2k
views
Two questions about pathifier package
pathways statistics microarray
6.3 years ago arronar • 0
2
votes
4
replies
1.2k
views
Removing batch effect on edgeR when interactons are looked at
rnaseq edger statistics model matrix
updated 6.6 years ago by ★ 13k • written 6.6 years ago by ▴ 90
0
votes
0
replies
1.2k
views
Assigning stats to differential peak locations relative to TSS
chipseeker chipseq statistics
6.6 years ago rbronste ▴ 60
0
votes
0
replies
1.5k
views
Job: Research Scientist in Biostatistics/Bioinformatics
statistics genetics genomics R Job
7.2 years ago • updated 7.1 years ago Luo Weijun ★ 1.6k
50 results • Page 1 of 1
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Answer: Once again a "Model matrix not full rank" by swbarnes2 ★ 1.3k
Replicate numbers, like the 1 in control_1 are fine in sample names, but never add them to anything else in colData. From the computer's p…
Answer: limma Intercept vs No-intercept models completely changing DMR results? by Gordon Smyth 50k
I'll add a little bit of general advice to James' answer. You seem to have the misunderstanding that you can change the design matrix but …
Answer: package goseq seems to be not available on the latest version of R by Gordon Smyth 50k
It is true that goseq isn't available for Bioc 3.19. That is because goseq depends on txbmaker, which is itself not yet available for Bioc…
Answer: limma Intercept vs No-intercept models completely changing DMR results? by James W. MacDonald 65k
This part: ``` design_intercept <- model.matrix(~Alt+Sex+Age+PC1, data=targets_Sherpa) colnames(design_intercept) <- c("AltSHP_LA","Al…
Comment: CombineArrays for EPIC and EPIC V2 by Kim • 0
Thank you Tim, this is a great help in getting me started!
Votes
Answer: Why does GSEA on edgeR results for randomized samples give highly significant p-
Answer: limma Intercept vs No-intercept models completely changing DMR results?
Answer: CombineArrays for EPIC and EPIC V2
Answer: Too many significant genes when integrating gtex and tcga
Comment: Too many significant genes when integrating gtex and tcga
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